Cytotoxic T lymphocyte exocytosis: bring on the SNAREs!

Rab proteins as membrane organizers

2001 • 3,320 citations

SNAP receptors implicated in vesicle targeting and fusion

1993 • 3,220 citations

Membrane Fusion

1990 • 2,458 citations

THE SYNAPTIC VESICLE CYCLE

2004 • 2,413 citations

The Mechanisms of Vesicle Budding and Fusion

2004 • 1,738 citations

Membrane Fusion

2003 • 1,265 citations

SNARE-mediated membrane fusion

2001 • 1,121 citations

Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

2000 • 935 citations

Munc13-4 Is Essential for Cytolytic Granules Fusion and Is Mutated in a Form of Familial Hemophagocytic Lymphohistiocytosis (FHL3)

2003 • 905 citations

Cytotoxic T lymphocytes: all roads lead to death

2002 • 893 citations

The Immunological Synapse of CTL Contains a Secretory Domain and Membrane Bridges

2001 • 796 citations

Secretory lysosomes

2002 • 633 citations

SNAREs and traffic

2005 • 596 citations

Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11

2005 • 552 citations

Lysosome‐related organelles

2000 • 467 citations

The melanosome: membrane dynamics in black and white

2001 • 441 citations

Rab27a Is Required for Regulated Secretion in Cytotoxic T Lymphocytes

2001 • 415 citations

A mutation in Rab27a causes the vesicle transport defects observed in ashen mice

2000 • 402 citations

Linking Albinism and Immunity: The Secrets of Secretory Lysosomes

2004 • 361 citations

The ins and outs of IgE-dependent mast-cell exocytosis

2004 • 316 citations

Identification of SNAREs Involved in Synaptotagmin VII-regulated Lysosomal Exocytosis

2004 • 311 citations

Lysosome-related organelles

2000 • 288 citations

Fusion of Cells by Flipped SNAREs

2003 • 248 citations

Defective Granule Exocytosis in Rab27a-Deficient Lymphocytes from Ashen Mice

2001 • 245 citations

The human basophil: a new appreciation of its role in immune responses

2000 • 224 citations

Munc13-4 Is a GTP-Rab27-binding Protein Regulating Dense Core Granule Secretion in Platelets

2004 • 219 citations

The human basophil: a new appreciation of its role in immune responses

2000 • 215 citations

Versatile Role of Rab27 in Membrane Trafficking: Focus on the Rab27 Effector Families

2005 • 213 citations

Distinct SNARE complexes mediating membrane fusion in Golgi transport based on combinatorial specificity

2002 • 208 citations

Munc13-4 Is an Effector of Rab27a and Controls Secretion of Lysosomes in Hematopoietic Cells

2004 • 206 citations

Vamp-7 Mediates Vesicular Transport from Endosomes to Lysosomes

1999 • 202 citations

Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoform

2000 • 168 citations

Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes

2004 • 158 citations

Vesicle-associated Membrane Protein 4 is Implicated inTrans-Golgi Network Vesicle Trafficking

1999 • 141 citations

CTL secretory lysosomes: biogenesis and secretion of a harmful organelle

2004 • 126 citations

Role of Calcium Influx in Cytotoxic T Lymphocyte Lytic Granule Exocytosis during Target Cell Killing

2001 • 121 citations

Molecular mechanisms of platelet exocytosis: role of SNAP-23 and syntaxin 2 and 4 in lysosome release

2000 • 117 citations

Syntaxin 11 is associated with SNAP-23 on late endosomes and the trans-Golgi network

1999 • 116 citations

Biochemical and functional characterization of Rab27a mutations occurring in Griscelli syndrome patients

2003 • 97 citations

SNAP-23 in rat kidney: colocalization with aquaporin-2 in collecting duct vesicles

1998 • 84 citations

Syntaxin 11 is an atypical SNARE abundant in the immune system

2000 • 76 citations

Testing the 3Q:1R “Rule”: Mutational Analysis of the Ionic “Zero” Layer in the Yeast Exocytic SNARE Complex Reveals No Requirement for Arginine

2000 • 74 citations

A Novel Synaptobrevin/VAMP Homologous Protein (VAMP5) Is Increased during In Vitro Myogenesis and Present in the Plasma Membrane

1998 • 74 citations

Identification of novel MUNC13-4 mutations in familial haemophagocytic lymphohistiocytosis and functional analysis of MUNC13-4-deficient cytotoxic T lymphocytes

2004 • 72 citations

Tissue Distribution of SNAP-23 and Its Subcellular Localization in 3T3-L1 Cells

1997 • 68 citations

Syntaxin 11: A Member of the Syntaxin Family without a Carboxyl Terminal Transmembrane Domain

1998 • 58 citations

Griscelli Syndrome: Characterization of a New Mutation and Rescue of T-Cytotoxic Activity by Retroviral Transfer of RAB27A Gene

2004 • 50 citations

Involvement of Rab27 in antigen-induced histamine release from rat basophilic leukemia 2H3 cells

2004 • 41 citations

T cell synapse assembly: proteins, motors and the underlying cell biology

2004 • 16 citations