Therapeutic effect of epigallocatechin-3-gallate in a mouse model of colitis

Inflammatory bowel disease: Etiology and pathogenesis

1998 • 2,095 citations

Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity

1984 • 1,746 citations

Epithelial NEMO links innate immunity to chronic intestinal inflammation

2007 • 1,022 citations

Inhibition of Carcinogenesis by Tea

2002 • 947 citations

Local administration of antisense phosphorothiate olignucleotides to the p65 subunit of NF–κB abrogates established experimental colitis in mice

1996 • 839 citations

Activation of nuclear factor kappa B in inflammatory bowel disease

1998 • 736 citations

Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa

1998 • 696 citations

The green tea polyphenol, (−)-epigallocatechin-3-gallate blocks nuclear factor-kappa B activation by inhibiting ikappaB kinase activity in the intestinal epithelial cell line, IEC-6

2001 • 362 citations

Cytokine Gene Transcription By NF‐κB Family Members in Patients with Inflammatory Bowel Disease

1998 • 223 citations

A murine model of chronic inflammation-induced intestinal fibrosis down-regulated by antisense NF-κB

2003 • 207 citations

Epigallocatechin, a Green Tea Polyphenol, Attenuates Myocardial Ischemia Reperfusion Injury in Rats

2004 • 181 citations

Nuclear factor-κB as a therapeutic target in critical care medicine

2003 • 172 citations

Green Tea Polyphenol Extract Attenuates Inflammation in Interleukin-2–Deficient Mice, a Model of Autoimmunity

2001 • 158 citations

Blockade of poly(ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis

1999 • 145 citations

The medicinal chemistry of tea

2004 • 140 citations

Antioxidants of the Beverage Tea in Promotion of Human Health

2004 • 130 citations

Gnotobiotic IL-10−/−;NF-κBEGFP Mice Reveal the Critical Role of TLR/NF-κB Signaling in Commensal Bacteria-Induced Colitis

2007 • 117 citations

Effects of steroid treatment on activation of nuclear factor κB in patients with inflammatory bowel disease

1998 • 112 citations

Epigallocatechin gallate attenuates adhesion and migration of CD8+ T cells by binding to CD11b

2004 • 97 citations

Intracellular signaling network as a prime chemopreventive target of (–)‐epigallocatechin gallate

2006 • 95 citations

Green tea polyphenol extract attenuates colon injury induced by experimental colitis

2005 • 88 citations

Epigallocatechin-3-gallate Impairs Chemokine Production in Human Colon Epithelial Cell Lines

2005 • 86 citations

Activator protein‐1 signalling pathway and apoptosis are modulated by poly(ADP‐ribose) polymerase‐1 in experimental colitis

2004 • 66 citations

Germinated barley foodstuffs attenuate colonic mucosal damage and mucosal nuclear factor kappa B activity in a spontaneous colitis model

1999 • 65 citations

Thearubigin, the major polyphenol of black tea, ameliorates mucosal injury in trinitrobenzene sulfonic acid-induced colitis

2003 • 64 citations

Role of the Retinoblastoma (pRb)–E2F/DP Pathway in Cancer Chemopreventive Effects of Green Tea Polyphenol Epigallocatechin-3-gallate

2002 • 62 citations

Green Tea Suppresses Lipopolysaccharide-Induced Liver Injury in D-Galactosamine–Sensitized Rats

2001 • 61 citations

Legionella pneumophilaReplication in Macrophages Inhibited by Selective Immunomodulatory Effects on Cytokine Formation by Epigallocatechin Gallate, a Major Form of Tea Catechins

2001 • 60 citations

Inhibitors of poly (ADP-ribose) polymerase modulate signal transduction pathways in colitis

2003 • 50 citations

Down-Regulation of Endothelial Adhesion Molecules and Leukocyte Adhesion by Treatment with Superoxide Dismutase Is Beneficial in Chronic Immune Experimental Colitis

2005 • 50 citations

Systemic and Local Cytokine Production in Quiescent Ulcerative Colitis and Its Relationship to Future Relapse: A Prospective Pilot Study

2005 • 48 citations

Fas activates the JNK pathway in human colonic epithelial cells: lack of a direct role in apoptosis

1999 • 46 citations

Epigallocatechin Gallate Modulates Cytokine Production by Bone Marrow-Derived Dendritic Cells Stimulated with Lipopolysaccharide or Muramyldipeptide, or Infected with Legionella pneumophila

2005 • 44 citations

THE GREEN TEA POLYPHENOL EPIGALLOCATECHIN-3-GALLATE IMPROVES SYSTEMIC HEMODYNAMICS AND SURVIVAL IN RODENT MODELS OF POLYMICROBIAL SEPSIS

2007 • 44 citations

The free radical scavenger edaravone suppresses experimental dextran sulfate sodium-induced colitis in rats

2003 • 35 citations

Activation of the CD2 Pathway in Lamina Propria T Cells Up-Regulates Functionally Active AP-1 Binding to the IL-2 Promoter, Resulting in Messenger RNA Transcription and IL-2 Secretion

1998 • 24 citations