Protein Kinase Cα Regulates Human Monocyte O·̄2Production and Low Density Lipoprotein Lipid Oxidation

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

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Practical Methods for Plasma Lipoprotein Analysis1 1Work supported in part by the U.S. Atomic Energy Commission and by grants (HE06222 and FR00102) from the U.S. Public Health Service.

1968 • 1,255 citations

Rapid microassays for the measurement of superoxide and hydrogen peroxide production by macrophages in culture using an automatic enzyme immunoassay reader

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Localization of Protein Kinases by Anchoring Proteins: a Theme in Signal Transduction

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Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia.

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The respiratory burst oxidase.

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Methods for Studying Mononuclear Phagocytes

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Monocytes and Neutrophils Oxidize Low Density Lipoprotein Making It Cytotoxic

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Protein kinase C isozymes and substrates

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THE INTERACTION OF SOLUBLE HORSERADISH PEROXIDASE WITH MOUSE PERITONEAL MACROPHAGES IN VITRO

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[17] Predicting optimal and suboptimal secondary structure for RNA

1990 • 383 citations

The phosphorylation of the respiratory burst oxidase component p47phox during neutrophil activation. Phosphorylation of sites recognized by protein kinase C and by proline-directed kinases.

1994 • 342 citations

Unsaturated fatty acids stimulate NADPH-dependent superoxide production by cell-free system derived from macrophages

1984 • 335 citations

Activation of the respiratory burst enzyme from human neutrophils in a cell-free system. Evidence for a soluble cofactor.

1985 • 334 citations

Activation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachidonic acid in a cell-free system.

1985 • 315 citations

Oxygen-mediated heterogeneity of apo-low-density lipoprotein.

1978 • 276 citations

Phosphorylation of the Respiratory Burst Oxidase Subunit p47 as Determined by Two-dimensional Phosphopeptide Mapping

1996 • 241 citations

Superoxide anion participation in human monocyte-mediated oxidation of low-density lipoprotein and conversion of low-density lipoprotein to a cytotoxin.

1989 • 231 citations

Activation of the human neutrophil nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase by protein kinase C.

1985 • 216 citations

NADPH oxidase of neutrophils

1996 • 208 citations

Translocation Inhibitors Define Specificity of Protein Kinase C Isoenzymes in Pancreatic β-Cells

1997 • 173 citations

The oxidative modification of low-density lipoproteins by macrophages

1990 • 169 citations

A possible role for protein phosphorylation in the activation of the respiratory burst in human neutrophils. Evidence from studies with cells from patients with chronic granulomatous disease.

1986 • 168 citations

Protein kinase C isotypes and signaling in neutrophils. Differential substrate specificities of a translocatable calcium- and phospholipid-dependent beta-protein kinase C and a phospholipid-dependent protein kinase which is inhibited by long chain fatty acyl coenzyme A

1991 • 163 citations

Phosphatidic Acid-mediated Phosphorylation of the NADPH Oxidase Component p47-phox

1997 • 140 citations

Protein Kinase C in the Transduction of Signals Toward and within the Cell Nucleus

1995 • 137 citations

Protein kinase C isotypes in human erythroleukemia cell proliferation and differentiation

1992 • 107 citations

Isozymes of protein kinase C in human neutrophils and their modification by two endogenous proteinases.

1990 • 106 citations

Redistribution of protein kinase C activity in human monocytes: correlation with activation of the respiratory burst.

1985 • 101 citations

Activation of NADPH oxidase of human neutrophils involves the phosphorylation and the translocation of cytosolic p67phox

1993 • 101 citations

Protein Kinase C in the Transduction of Signals Toward and within the Cell Nucleus

1995 • 98 citations

Arachidonic acid acts as an intracellular activator of NADPH-oxidase in Fc gamma receptor-mediated superoxide generation in macrophages.

1987 • 98 citations

Kinase-dependent Activation of the Leukocyte NADPH Oxidase in a Cell-free System

1997 • 81 citations

Induction of 15-Lipoxygenase Expression by IL-13 Requires Tyrosine Phosphorylation of Jak2 and Tyk2 in Human Monocytes

1998 • 81 citations

Selective Inhibition of Cytosolic Phospholipase A2 in Activated Human Monocytes

1997 • 61 citations

Role of protein kinase C isozymes in Fc gamma receptor-mediated intracellular killing of Staphylococcus aureus by human monocytes.

1995 • 56 citations

Protein kinase C activity is required for lipid oxidation of low density lipoprotein by activated human monocytes

1994 • 51 citations

The Fatty Acid Bimodal Action on Superoxide Anion Production by Human Adherent Monocytes under Phorbol 12-Myristate 13-Acetate or Diacylglycerol Activation Can Be Explained by the Modulation of Protein Kinase C and p47 Translocation

1995 • 42 citations

Dual Ca2+ requirement for optimal lipid peroxidation of low density lipoprotein by activated human monocytes.

1993 • 41 citations

Protein kinase C activation in human monocytes: regulation of PKC isoforms.

1993 • 39 citations

Legionella pneumophila inhibits superoxide generation in human monocytes via the down-modulation of α and β protein kinase C isotypes

1994 • 30 citations

Protein kinase C regulates TNF-alpha production by human monocytes.

1993 • 29 citations

10. Atherosclerosis and Coronary Disease

1966 • 18 citations

Signal transduction in human monocytes: Relationship between superoxide production and the level of kinase C in the membrane

1986 • 17 citations

Activation of the leukocyte NADPH oxidase in a cell-free system: phosphorylation vs. amphiphiles.

1998 • 10 citations

Activation of PKC, superoxide anion production and LDL lipid peroxidation are not dependent on phosphoinositide-specific phospholipase C activity in U937 cells

1997 • 4 citations