Mutational analysis of the human HSP70 protein: distinct domains for nucleolar localization and adenosine triphosphate binding.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

Speculations on the functions of the major heat shock and glucose-regulated proteins

1986 • 1,574 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

An hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

1986 • 1,457 citations

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1984 • 1,278 citations

70K heat shock related proteins stimulate protein translocation into microsomes

1988 • 1,276 citations

Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.

1985 • 860 citations

The Heat Shock Respons

1985 • 809 citations

Uncoating ATPase is a member of the 70 kilodalton family of stress proteins

1986 • 607 citations

Inhibition of restriction endonuclease Nel I cleavage by phosphorothioate groups and its application to oligonucleotide-directed mutagenesis

1986 • 560 citations

Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells.

1984 • 522 citations

Cellular and biochemical events in mammalian cells during and after recovery from physiological stress.

1986 • 513 citations

Major heat shock gene of Drosophila and the Escherichia coli heat-inducible dnaK gene are homologous.

1984 • 513 citations

Structure and expression of the human gene encoding major heat shock protein HSP70.

1985 • 461 citations

Hsp70 accelerates the recovery of nucleolar morphology after heat shock.

1984 • 456 citations

70-kD heat shock-related protein is one of at least two distinct cytosolic factors stimulating protein import into mitochondria.

1988 • 380 citations

Rapid purification of mammalian 70,000-dalton stress proteins: affinity of the proteins for nucleotides.

1985 • 365 citations

Specific interaction between the p53 cellular tumour antigen and major heat shock proteins

1986 • 354 citations

Nuclear location signals in polyoma virus large-T

1986 • 351 citations

Involvement of ATP in the nuclear and nucleolar functions of the 70 kd heat shock protein.

1985 • 327 citations

Human HSP70 promoter contains at least two distinct regulatory domains.

1986 • 326 citations

Expression of human HSP70 during the synthetic phase of the cell cycle.

1986 • 316 citations

Sequence requirements for nucleolar localization of human T cell leukemia virus type I pX protein, which regulates viral RNA processing

1988 • 308 citations

The 70-kd mammalian heat shock proteins are structurally and functionally related to the uncoating protein that releases clathrin triskelia from coated vesicles.

1985 • 301 citations

Identification of the Human c-myc Protein Nuclear Translocation Signal

1988 • 299 citations

The ATPase core of a clathrin uncoating protein.

1987 • 259 citations

Complex regulation of heat shock- and glucose-responsive genes in human cells.

1988 • 242 citations

Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines.

1987 • 237 citations

Characterization of the thermotolerant cell. II. Effects on the intracellular distribution of heat-shock protein 70, intermediate filaments, and small nuclear ribonucleoprotein complexes.

1988 • 195 citations

Seventy-kilodalton heat shock proteins and an additional component from reticulocyte lysate stimulate import of M13 procoat protein into microsomes.

1988 • 187 citations

The nuclear migration signal of Xenopus laevis nucleoplasmin.

1987 • 176 citations

Use of peptide tagging to detect proteins expressed from cloned genes: deletion mapping functional domains of Drosophila hsp 70.

1984 • 175 citations

Pentapeptide nuclear localization signal in adenovirus E1a.

1987 • 165 citations

Constitutively Expressed Rat mRNA Encoding a 70-Kilodalton Heat-Shock-Like Protein

1985 • 164 citations

SV40 DNA transfection of cells in suspension: analysis of the efficiency of transcription and translation of T-antigen

1981 • 161 citations

The grpE protein of Escherichia coli. Purification and properties.

1987 • 160 citations

Structure and Expression of the Human Gene Encoding Major Heat Shock Protein HSP70

1985 • 155 citations

Cell cycle-dependent association of HSP70 with specific cellular proteins.

1989 • 145 citations

Epitopes of human testis-specific lactate dehydrogenase deduced from a cDNA sequence.

1987 • 112 citations

Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP.

1988 • 106 citations

Rapid Purification of Mammalian 70,000-Dalton Stress Proteins: Affinity of the Proteins for Nucleotides

1985 • 104 citations

Complex Regulation of Heat Shock- and Glucose-Responsive Genes in Human Cells

1988 • 77 citations

Differential distribution of the adenovirus E1A proteins and colocalization of E1A with the 70-kilodalton cellular heat shock protein in infected cells

1988 • 66 citations

Medium tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with 73-kilodalton heat shock protein

1987 • 62 citations

Immunological Evidence for the Association of P53 with a Heat Shock Protein, hsc70, in p53-plus-ras-Transformed Cell Lines

1987 • 56 citations

Purification of Complexes of Nuclear Oncogene p53 with Rat and Escherichia coli Heat Shock Proteins: In Vitro Dissociation of hsc70 and dnaK from Murine p53 by ATP

1988 • 28 citations