Enhancement of arsenic trioxide‐mediated apoptosis using docosahexaenoic acid in arsenic trioxide‐resistant solid tumor cells

Use of Arsenic Trioxide (As2O3 ) in the Treatment of Acute Promyelocytic Leukemia (APL): II. Clinical Efficacy and Pharmacokinetics in Relapsed Patients

1997 • 1,431 citations

Complete Remission after Treatment of Acute Promyelocytic Leukemia with Arsenic Trioxide

1998 • 1,220 citations

Mechanisms of action of arsenic trioxide.

2002 • 943 citations

United States Multicenter Study of Arsenic Trioxide in Relapsed Acute Promyelocytic Leukemia

2001 • 825 citations

Arsenic Trioxide Selectively Induces Acute Promyelocytic Leukemia Cell Apoptosis Via a Hydrogen Peroxide-Dependent Pathway

1999 • 539 citations

Arsenic Trioxide and Melarsoprol Induce Programmed Cell Death in Myeloid Leukemia Cell Lines and Function in a PML and PML-RAR Independent Manner

1998 • 228 citations

Tumor growth inhibition by arsenic trioxide (As2O3) in the orthotopic metastasis model of androgen-independent prostate cancer.

2001 • 194 citations

Arsenic trioxide-mediated cytotoxicity and apoptosis in prostate and ovarian carcinoma cell lines.

2000 • 191 citations

Arsenic trioxide induces apoptosis in neuroblastoma cell lines through the activation of caspase 3 in vitro

1999 • 188 citations

Enhancement of doxorubicin cytotoxicity by polyunsaturated fatty acids in the human breast tumor cell line MBA-MB-231: Relationship to lipid peroxidation

1998 • 157 citations

Cellular Enrichment with Polyunsaturated Fatty Acids Induces an Oxidative Stress and Activates the Transcription Factors AP1 and NFκB

1999 • 155 citations

Induction of apoptosis and inhibition of human gastric cancer MGC-803 cell growth by arsenic trioxide

1999 • 147 citations

Effects of gamma-linolenic acid and oleic acid on paclitaxel cytotoxicity in human breast cancer cells

2001 • 144 citations

Arsenic trioxide inhibits the growth of A498 renal cell carcinoma cells via cell cycle arrest or apoptosis

2003 • 117 citations

Dietary menhaden oil enhances mitomycin C antitumor activity toward human mammary carcinoma MX‐1

1995 • 99 citations

Docosahexaenoic acid enhances arsenic trioxide–mediated apoptosis in arsenic trioxide–resistant HL-60 cells

2003 • 88 citations

Effect of Arsenic Trioxide on Cell Cycle Arrest in Head and Neck Cancer Cell Line PCI-1

1999 • 78 citations

Arsenic trioxide and ascorbic acid: synergy with potential implications for the treatment of acute myeloid leukaemia?

2001 • 71 citations

Clinical Experience of Arsenic Trioxide in Relapsed Acute Promyelocytic Leukemia

2001 • 67 citations

Influence of docosahexaenoic acid in vitro on intracellular adriamycin concentration in lymphocytes and human adriamycin‐sensitive and ‐resistant small‐cell lung cancer cell lines, and on cytotoxicity in the tumor cell lines

1987 • 62 citations

Therapy of acute promyelocytic leukemia: all-trans retinoic acid and beyond.

1998 • 50 citations

Dietary n‐3 polyunsaturated fatty acids and oxidants increase rat mammary tumor sensitivity to epirubicin without change in cardiac toxicity

1999 • 38 citations

DHA feeding provides host protection and prevents fibrosarcoma‐induced hyperlipidemia while maintaining the tumor response to araC in Fischer 344 rats

1997 • 25 citations