Activation of phospholipase C in human B cells is dependent on tyrosine phosphorylation.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

1987 • 3,773 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

EGF induces tyrosine phosphorylation of phospholipase C-II: A potential mechanism for EGF receptor signaling

1989 • 784 citations

Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors

1989 • 607 citations

Blocking of EGF-Dependent Cell Proliferation by EGF Receptor Kinase Inhibitors

1988 • 593 citations

T Cell Antigen Receptor-Mediated Activation of Phospholipase C Requires Tyrosine Phosphorylation

1990 • 476 citations

Stimulation of protein tyrosine phosphorylation by the B-lymphocyte antigen receptor

1990 • 346 citations

B lymphocyte receptors and polyphosphoinositide degradation

1985 • 332 citations

Protein tyrosine phosphorylation is induced in murine B lymphocytes in response to stimulation with anti-immunoglobulin.

1990 • 225 citations

The effect of quercetin on the phosphorylatio activity of the Rous sarcoma virus transforming gene product in vitro and in vivo

1983 • 177 citations

A guanine nucleotide-dependent phosphatidylinositol 4,5-diphosphate phospholipase C in cells transformed by the v-fms and v-fes oncogenes.

1986 • 168 citations

The role of class II molecules in human B cell activation. Association with phosphatidyl inositol turnover, protein tyrosine phosphorylation, and proliferation.

1990 • 156 citations

Interleukin 2-induced tyrosine phosphorylation. Interleukin 2 receptor beta is tyrosine phosphorylated.

1990 • 149 citations

Activation of human B cells and inhibition of their terminal differentiation by monoclonal anti-mu antibodies.

1985 • 82 citations

Depletion of CD8+ cells in human thymic medulla results in selective immune deficiency.

1989 • 76 citations

Inhibition of insulin-dependent lipogenesis and anti-lipolysis by protein tyrosine kinase inhibitors.

1989 • 59 citations

Abortive activation of B lymphocytes by monoclonal anti-immunoglobulin antibodies.

1986 • 40 citations

Human B cell activation. Evidence for diverse signals provided by various monoclonal anti-IgM antibodies.

1985 • 31 citations

Enhanced tyrosine phosphorylation in B lymphocytes upon complexing of membrane immunoglobulin

1984 • 22 citations

Induction of human B cell proliferation and differentiation by the combination of phorbol ester and ionomycin

1987 • 17 citations

Response of human B cells to different anti‐immunoglobulin isotypes: Absence of a correlation between early activation events and cell proliferation

1987 • 15 citations

Antigen-induced proliferation and immunoglobulin A secretion by a human-human hybridoma.

1987 • 4 citations