The Inhibitor of Apoptosis Protein Fusion c-IAP2·MALT1 Stimulates NF-κB Activation Independently of TRAF1 AND TRAF2

The PyMOL Molecular Graphics System

2002 • 18,218 citations

NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation

1998 • 2,698 citations

NF-κB in cancer: from innocent bystander to major culprit

2002 • 2,457 citations

IAP proteins: blocking the road to death's door

2002 • 1,753 citations

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1995 • 1,237 citations

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1994 • 1,043 citations

Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma

2000 • 978 citations

Structural basis of IAP recognition by Smac/DIABLO

2000 • 844 citations

The Apoptosis Inhibitor Gene API2 and a Novel 18q Gene,MLT, Are Recurrently Rearranged in the t(11;18)(q21;q21) Associated With Mucosa-Associated Lymphoid Tissue Lymphomas

1999 • 714 citations

Mechanism of XIAP-Mediated Inhibition of Caspase-9

2003 • 675 citations

The TRAF6 Ubiquitin Ligase and TAK1 Kinase Mediate IKK Activation by BCL10 and MALT1 in T Lymphocytes

2004 • 674 citations

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

2000 • 625 citations

IAPs, RINGs and ubiquitylation

2005 • 591 citations

The CARD domain: a new apoptotic signalling motif

1997 • 532 citations

Bcl10 activates the NF-κB pathway through ubiquitination of NEMO

2003 • 524 citations

Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.

1996 • 515 citations

RIP2 Is a Novel NF-κB-activating and Cell Death-inducing Kinase

1998 • 425 citations

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

1996 • 415 citations

Bcl10 and MALT1, Independent Targets of Chromosomal Translocation in MALT Lymphoma, Cooperate in a Novel NF-κB Signaling Pathway

2001 • 409 citations

ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

2000 • 407 citations

Structural basis for self-association and receptor recognition of human TRAF2

1999 • 355 citations

A novel gene, MALT1 at 18q21, is involved in t(11;18) (q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue

1999 • 354 citations

An exegesis of IAPs: salvation and surprises from BIR motifs

1999 • 345 citations

Variable frequencies of t(11;18)(q21;q21) in MALT lymphomas of different sites: significant association with CagA strains of H pylori in gastric MALT lymphoma

2003 • 325 citations

Molecular Determinants of Kinase Pathway Activation by Apo2 Ligand/Tumor Necrosis Factor-related Apoptosis-inducing Ligand

2005 • 270 citations

Caspase activation – stepping on the gas or releasing the brakes? Lessons from humans and flies

2004 • 235 citations

A Role for NF-κB Essential Modifier/IκB Kinase-γ (NEMO/IKKγ) Ubiquitination in the Activation of the IκB Kinase Complex by Tumor Necrosis Factor-α

2003 • 209 citations

A Novel Mechanism of TRAF Signaling Revealed by Structural and Functional Analyses of the TRADD–TRAF2 Interaction

2000 • 185 citations

Breakpoints of the t(11;18)(q21;q21) in mucosa-associated lymphoid tissue (MALT) lymphoma lie within or near the previously undescribed gene MALT1 in chromosome 18.

1999 • 169 citations

SMAC Negatively Regulates the Anti-apoptotic Activity of Melanoma Inhibitor of Apoptosis (ML-IAP)

2002 • 161 citations

Distinct BIR Domains of cIAP1 Mediate Binding to and Ubiquitination of Tumor Necrosis Factor Receptor-associated Factor 2 and Second Mitochondrial Activator of Caspases

2005 • 159 citations

Update on MALT lymphomas

2005 • 137 citations

Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP

2004 • 137 citations

Constitutive NF-κB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity

2005 • 135 citations

cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas

2005 • 98 citations

Structure and Function Analysis of Peptide Antagonists of Melanoma Inhibitor of Apoptosis (ML-IAP)

2003 • 95 citations

Characteristics of the caspase-like catalytic domain of human paracaspase

2004 • 37 citations

Mass spectrometric analysis of tumor necrosis factor receptor‐associated factor 1 ubiquitination mediated by cellular inhibitor of apoptosis 2

2004 • 30 citations