Chronic granulomatous disease—Pieces of a cellular and molecular puzzle

Biological Defense Mechanisms. THE PRODUCTION BY LEUKOCYTES OF SUPEROXIDE, A POTENTIAL BACTERICIDAL AGENT

1973 • 2,955 citations

The Metabolic Basis of Inherited Disease.

1983 • 2,885 citations

Active Oxygen Species and the Functions of Phagocytic Leukocytes

1980 • 1,124 citations

Quantitative Nitroblue Tetrazolium Test in Chronic Granulomatous Disease

1968 • 894 citations

Cloning the gene for an inherited human disorder—chronic granulomatous disease—on the basis of its chromosomal location

1986 • 839 citations

Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22,000.

1987 • 459 citations

Unsaturated fatty acids stimulate NADPH-dependent superoxide production by cell-free system derived from macrophages

1984 • 335 citations

Absence of both cytochrome b−245 subunits from neutrophils in X-linked chronic granulomatous disease

1987 • 324 citations

Activation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachidonic acid in a cell-free system.

1985 • 315 citations

Absence of Cytochrome b_-245in Chronic Granulomatous Disease

1983 • 300 citations

Chronic Granulomatous Disease

1983 • 266 citations

Recent Advances in Chronic Granulomatous Disease

1983 • 236 citations

Chronic Granulomatous Disease

1987 • 204 citations

Activation of neutrophil NADPH oxidase in a cell-free system. Partial purification of components and characterization of the activation process.

1987 • 202 citations

Regulation of neutrophil NADPH oxidase activation in a cell-free system by guanine nucleotides and fluoride. Evidence for participation of a pertussis and cholera toxin-insensitive G protein.

1987 • 188 citations

A NEWLY DEFINED X-LINKED TRAIT IN MAN WITH DEMONSTRATION OF THE LYON EFFECT IN CARRIER FEMALES

1967 • 184 citations

A possible role for protein phosphorylation in the activation of the respiratory burst in human neutrophils. Evidence from studies with cells from patients with chronic granulomatous disease.

1986 • 168 citations

Mechanism of the superoxide-producing oxidase of neutrophils. O2 is necessary for the fast reduction of cytochrome b-245 by NADPH

1985 • 126 citations

The respiratory burst oxidase of human neutrophils. Further studies of the purified enzyme.

1986 • 113 citations

Further evidence for the involvement of a phosphoprotein in the respiratory burst oxidase of human neutrophils

1986 • 111 citations

Cytochrome b deficiency in an autosomal form of chronic granulomatous disease. A third form of chronic granulomatous disease recognized by monocyte hybridization.

1985 • 88 citations

Solubilization of the O2(-)-forming activity responsible for the respiratory burst in human neutrophils.

1978 • 84 citations

Complementation in monocyte hybrids revealing genetic heterogeneity in chronic granulomatous disease

1984 • 80 citations

Neutrophil oxygen reduction: The enzymes and the products

1985 • 80 citations

Chronic granulomatous disease--pieces of a cellular and molecular puzzle.

1973 • 76 citations

Reevaluation of cytochrome b and flavin adenine dinucleotide in neutrophils from patients with chronic granulomatous disease and description of a family with probable autosomal recessive inheritance of cytochrome b deficiency

1986 • 66 citations

A study of 25 patients with chronic granulomatous disease: A new classification by correlating respiratory burst, cytochrome b, and flavoprotein

1986 • 63 citations

NADPH binding component of neutrophil superoxide-generating oxidase.

1986 • 61 citations

Phosphoproteins and the activation of the neutrophil respiratory burst oxidase

1987 • 2 citations