Spinal and supraspinal opioid analgesia in the mouse: the role of subpopulations of opioid binding sites

A METHOD FOR DETERMINING LOSS OF PAIN SENSATION

1941 • 3,174 citations

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

1976 • 2,883 citations

Studies on the direct spinal action of narcotics in the production of analgesia in the rat.

1977 • 543 citations

Classification of multiple morphine and enkephalin binding sites in the central nervous system.

1981 • 372 citations

Multiplicative interaction between narcotic agonisms expressed at spinal and supraspinal sites of antinociceptive action as revealed by concurrent intrathecal and intracerebroventricular injections of morphine.

1980 • 272 citations

On the central sites for the antinociceptive action of morphine and fentanyl

1970 • 265 citations

Opiate Analgesia: Evidence for Mediation by a Subpopulation of Opiate Receptors

1980 • 249 citations

The analgesic effectiveness of nalorphine and nalorphine-morphine combinations in man.

1954 • 190 citations

Naloxazone, a long-acting opiate antagonist: effects on analgesia in intact animals and on opiate receptor binding in vitro.

1980 • 170 citations

Metkephamid, a Systemically Active Analog of Methionine Enkephalin with Potent Opioid δ-Receptor Activity

1981 • 110 citations

Long-acting opiate agonists and antagonists: 14-hydroxydihydromorphinone hydrazones

1980 • 103 citations

Multiple opiate receptors: [3H]ethylketocyclazocine receptor binding and ketocyclazocine analgesia.

1980 • 91 citations

Sites of antinociceptive action of systemically injected morphine: involvement of supraspinal loci as revealed by intracerebroventricular injection of naloxone.

1980 • 81 citations

Opiates and enkephalins: A common binding site mediates their analgesic actions in rats

1981 • 68 citations

The binding and analgesic properties of a sigma opiate, SKF 10,047.

1981 • 53 citations

Naloxazone irreversibly inhibits the high affinity binding of [125I]D-ala2-D-leu5-enkephalin

1981 • 48 citations

The binding of kappa- and sigma-opiates in rat brain

1982 • 39 citations

Delineation of the skin-twitch response in dogs and the effects thereon of morphine, thiopental and mephenesin.

1951 • 21 citations

Metkephamid (Tyr-D-Ala-Gly-Phe-N(Me)Met-NH2), a potent opioid peptide: Receptor binding and analgesic properties

1982 • 20 citations