Chapter 5 Interactions between photoexcited rhodopsin and light-activated enzymes in rods

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Flow of information in the light-triggered cyclic nucleotide cascade of vision.

1981 • 740 citations

Rhodopsin content in the outer segment membranes of bovine and frog retinal rods

1974 • 730 citations

Tautomeric Forms of Metarhodopsin

1963 • 602 citations

Light- and GTP-regulated interaction of GTPase and other proteins with bovine photoreceptor membranes

1980 • 561 citations

The structure of bovine rhodopsin

1983 • 513 citations

Isolation and characterization of cGMP phosphodiesterase from bovine rod outer segments.

1979 • 448 citations

Light-dependent phosphorylation of rhodopsin: number of phosphorylation sites

1982 • 441 citations

Rhodopsin and bacteriorhodopsin: structure—function relationships

1982 • 430 citations

Photolyzed rhodopsin catalyzes the exchange of GTP for bound GDP in retinal rod outer segments.

1980 • 391 citations

Light dependent phosphorylation of rhodopsin by ATP

1972 • 370 citations

Light-activated phosphodiesterase of the rod outer segment. Kinetics and parameters of activation and deactivation.

1978 • 353 citations

Purification and characterization of the gamma regulatory subunit of the cyclic GMP phosphodiesterase from retinal rod outer segments.

1982 • 336 citations

Phosphorylation of Frog Photoreceptor Membranes induced by Light

1972 • 332 citations

Light-regulated binding of rhodopsin kinase and other proteins to cattle photoreceptor membranes

1978 • 313 citations

Lateral Diffusion of Visual Pigment in Photoreceptor Disk Membranes

1974 • 302 citations

Purification and properties of the light-activated cyclic nucleotide phosphodiesterase of rod outer segments

1975 • 271 citations

Photoisomerization, energy storage, and charge separation: A model for light energy transduction in visual pigments and bacteriorhodopsin

1979 • 270 citations

Complex formation between metarhodopsin II and GTP‐binding protein in bovine protoreceptor membranes leads to a shift of the photoproduct equilibrium

1982 • 259 citations

ATP mediates rapid reversal of cyclic GMP phosphodiesterase activation in visual receptor membranes

1980 • 251 citations

Interactions between photoexcited rhodopsin and GTP-binding protein: kinetic and stoichiometric analyses from light-scattering changes.

1981 • 247 citations

Immunocytochemical localization of a large intrinsic membrane protein to the incisures and margins of frog rod outer segment disks.

1978 • 238 citations

In Situ Microspectrophotometric Studies on the Pigments of Single Retinal Rods

1962 • 222 citations

Energy uptake in the first step of visual excitation

1979 • 216 citations

A light-activated GTPase in vertebrate photoreceptors: Regulation of light-activated cyclic GMP phosphodiesterase

1977 • 208 citations

Amplitude, kinetics, and reversibility of a light-induced decrease in guanosine 3',5'-cyclic monophosphate in frog photoreceptor membranes.

1979 • 186 citations

Membrane-dependent guanine nucleotide binding and GTPase activities of soluble protein from bovine rod cell outer segments.

1979 • 183 citations

Phosphorylation of rhodopsin in bovine photoreceptor membranes. Dark reaction after illumination

1973 • 179 citations

Mechanism of ATP quench of phosphodiesterase activation in rod disc membranes.

1983 • 144 citations

Evidence that cyclic GMP regulates membrane potential in rod photoreceptors

1979 • 144 citations

Light-Induced Interaction between Rhodopsin and the GTP-Binding Protein. Metarhodopsin II Is the Major Photoproduct Involved

1982 • 142 citations

Light-induced binding of guanosinetriphosphatase to bovine photoreceptor membranes: effect of limited proteolysis of the membranes

1981 • 136 citations

Neutron diffraction studies of retinal rod outer segment membranes

1976 • 134 citations

Light dissociates enzymatically-cleaved rhodopsin into two different fragments

1975 • 130 citations

Light-induced dephosphorylation of two proteins in frog rod outer segments: influence of cyclic nucleotides and calcium.

1979 • 129 citations

Light-stimulated phosphorylation of rhodopsin in the retina: the presence of a protein kinase that is specific for photobleached rhodopsin.

1975 • 129 citations

Light-dependent phosphorylation of rhodopsin in living frogs

1974 • 128 citations

Rhodopsin Cycle in the Living Eye of the Rat

1969 • 121 citations

Light-induced phosphorylation of rhodopsin in cattle photoreceptor membranes: substrate activation and inactivation

1977 • 120 citations

GTP hydrolysis in intact rod outer segments and the transmitter cycle in visual excitation

1979 • 108 citations

Chapter 10 Interactions of Rod Cell Proteins with the Disk Membrane: Influence of Light, Ionic Strength, and Nucleotides

1981 • 106 citations

The partial primary structure of bovine rhodopsin and its topography in the retinal rod cell disc membrane

1980 • 106 citations

Calcium and cyclic GMP regulation of light-sensitive protein phosphorylation in frog photoreceptor membranes.

1982 • 102 citations

Transverse location of the retinal chromophore of rhodopsin in rod outer segment disc membranes

1982 • 96 citations

Measurements of fast light-induced light-scattering and -absorption changes in outer segments of vertebrate light sensitive rod cells

1976 • 95 citations

Effects of injections of calcium and EGTA into the outer segments of retinal rods of Bufo marinus

1977 • 90 citations

Additional component required for activity and reconstitution of light-activated vertebrate photoreceptor GTPase.

1980 • 87 citations

Structure of isolated bovine rod outer segment membranes

1977 • 79 citations

The orientation of the chromophore of vertebrate rhodopsin in the “meta” intermediate states and the reversibility of the meta II-meta III transition

1979 • 73 citations

Shift in the relation between flash‐induced metarhodopsin I and metarhodopsin II within the first 10% rhodopsin bleaching in bovine disc membranes

1981 • 70 citations

Control of light-activated phosphorylation in frog photoreceptor membranes

1977 • 67 citations

[76] Light-regulated binding of proteins to photoreceptor membranes and its use for the purification of several rod cell proteins

1982 • 67 citations

Interaction between photoexcited rhodopsin and peripheral enzymes in frog retinal rods

1983 • 65 citations

The Chemistry of Vision

1982 • 64 citations

ORIENTATION OF AROMATIC RESIDUES IN RHODOPSIN. ROTATION OF ONE TRYPTOPHAN UPON THE META I→META II TRANSITION AFTER ILLUMINATION

1979 • 63 citations

Light-dependent conformational change at rhodopsin's cytoplasmic surface detected by increased susceptibility to proteolysis

1982 • 61 citations

LIGHT‐INDUCED PERTURBATION OF AROMATIC RESIDUES IN BOVINE RHODOPSIN AND BACTERIORHODOPSIN*

1979 • 60 citations

Light-regulated enzymes of vertebrate retinal rods.

1979 • 59 citations

Influence of light and calcium on guanosine 5'-triphosphate in isolated frog rod outer segments.

1979 • 58 citations

Protein phosphorylation in rod outer segments from bovine retina: Cyclic nucleotide-activated protein kinase and its endogenous substrate

1977 • 57 citations

Mechanism and specificity of rhodopsin phosphorylation

1975 • 55 citations

Calcium effects on frog retinal cyclic guanosine 3', 5'-monophosphate levels and their light-initiated rate of decay.

1980 • 53 citations

Flow of information in the light-triggered cyclic nucleotide cascade of vision

1981 • 53 citations

Reactions of the Sulfhydryl Groups of Membrane-Bound Bovine Rhodopsin

1978 • 50 citations

The Light-induced Proton Uptake in Bovine Retinal Outer Segment Fragments

1968 • 50 citations

Ca2+-dependent changes in cyclic GMP levels are not correlated with opening and closing of the light-dependent permeability of toad photoreceptors.

1982 • 50 citations

Rapid Light-Induced Changes in Near Infrared Transmission of Rods in Bufo marinus

1978 • 50 citations

Light-induced, reversible binding of proteins to bovine photoreceptor membranes. Influence of nucleotides

1980 • 47 citations

Circular dichroism, optical rotatory dispersion, and absorption studies on the conformation of bovine rhodopsin in situ and solubilized with detergent

1977 • 47 citations

Protein kinases of retinal rod outer segments: identification and partial characterization of cyclic nucleotide dependent protein kinase and rhodopsin kinase

1981 • 45 citations

Differential phosphorylation by GTP and ATP in isolated rod outer segments of the retina

1976 • 42 citations

Activation of rhodopsin phosphorylation is triggered by the lumirhodopsin–metarhodopsin I transition

1983 • 41 citations

Surfaces of rod photoreceptor disk membranes: light-activated enzymes.

1982 • 41 citations

Activation of phosphodiesterase in frog rod outer segment by an intermediate of rhodopsin photolysis. I.

1981 • 40 citations

Evidence for differently protonated forms of metarhodopsin II as intermediates in the decay of membrane-bound cattle rhodopsin

1978 • 37 citations

Light-induced axial and radial shrinkage effects and changes of the refractive index in isolated bovine rod outer segments and disc vesicles

1981 • 36 citations

Light‐activated hydrolysis of GTP and cyclic GMP in the rod outer segments.

1978 • 34 citations

Light-stimulated, magnesium-dependent ATPase in toad retinal rod outer segments

1978 • 33 citations

Evidence for structural changes in the photoreceptor disk membrane, enabled by magnesium ATPase activity and triggered by light

1979 • 33 citations

The decay of long-lived photoproducts in the isolated bullfrog rod outer segment: Relationship to other dark reactions

1975 • 28 citations

The carboxyl-terminal one-third of bovine rhodopsin: Its structure and function

1982 • 26 citations

GTPase from rod outer segments: Characterization by photoaffinity labeling and tryptic peptide mapping

1981 • 26 citations

Rhodopsin-to-metarhodopsin II transition triggers amplified changes in cytosol ATP and ADP in intact retinal rod outer segments.

1982 • 17 citations

A GTP-protein activator of phosphodiesterase which forms in response to bleached rhodopsin.

1981 • 16 citations

Soluble 5'-nucleotidase: purification and reversible binding to photoreceptor membranes

1982 • 15 citations

Light and gtp effects on the turbidity of frog visual membrane suspensions

1980 • 14 citations

Kinetics and saturation of light-induced near-infrared scattering changes in isolated bovine rod outer segments

1981 • 7 citations