Effect of Uncontrolled Diabetes on Plasma Ghrelin Concentrations and Ghrelin-Induced Feeding

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

1999 • 8,261 citations

Central nervous system control of food intake

2000 • 6,305 citations

Ghrelin induces adiposity in rodents

2000 • 3,915 citations

A role for ghrelin in the central regulation of feeding

2001 • 3,415 citations

A Preprandial Rise in Plasma Ghrelin Levels Suggests a Role in Meal Initiation in Humans

2001 • 2,865 citations

Gut hormone PYY3-36 physiologically inhibits food intake

2002 • 2,263 citations

Ghrelin, a Novel Growth Hormone-Releasing Acylated Peptide, Is Synthesized in a Distinct Endocrine Cell Type in the Gastrointestinal Tracts of Rats and Humans¹

2000 • 1,794 citations

The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis

2003 • 1,617 citations

The Novel Hypothalamic Peptide Ghrelin Stimulates Food Intake and Growth Hormone Secretion

2000 • 1,521 citations

Plasma Ghrelin Levels in Lean and Obese Humans and the Effect of Glucose on Ghrelin Secretion

2002 • 1,246 citations

Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin

2001 • 1,181 citations

Ghrelin Causes Hyperphagia and Obesity in Rats

2001 • 1,121 citations

Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

1996 • 1,020 citations

Ghrelin, an Endogenous Growth Hormone Secretagogue, Is a Novel Orexigenic Peptide That Antagonizes Leptin Action Through the Activation of Hypothalamic Neuropeptide Y/Y1 Receptor Pathway

2001 • 862 citations

Post-prandial decrease of circulating human ghrelin levels

2001 • 691 citations

Orexigenic Action of Peripheral Ghrelin Is Mediated by Neuropeptide Y and Agouti-Related Protein

2004 • 662 citations

Deletion of Ghrelin Impairs neither Growth nor Appetite

2003 • 631 citations

Inhibition of hypothalamic neuropeptide Y gene expression by insulin.

1992 • 533 citations

Insulin Regulates Plasma Ghrelin Concentration

2002 • 500 citations

Genetic approaches to studying energy balance: perception and integration

2002 • 401 citations

The influence of insulin on circulating ghrelin

2003 • 368 citations

Central Effect of Ghrelin, an Endogenous Growth Hormone Secretagogue, on Hypothalamic Peptide Gene Expression

2000 • 362 citations

Effect of Intracerebroventricular Insulin Infusion on Diabetic Hyperphagia and Hypothalamic Neuropeptide Gene Expression

1995 • 361 citations

Novel Expression and Functional Role of Ghrelin in Rat Testis

2002 • 344 citations

Kidney produces a novel acylated peptide, ghrelin

2000 • 336 citations

Roles for Ghrelin in the Regulation of Appetite and Body Weight

2003 • 282 citations

Vagotomy Dissociates Short- and Long-Term Controls of Circulating Ghrelin

2003 • 260 citations

Meal-Related Ghrelin Suppression Requires Postgastric Feedback

2003 • 232 citations

Intracerebroventricular Leptin Regulates Hepatic but Not Peripheral Glucose Fluxes

1998 • 229 citations

Insulin is Required for Prandial Ghrelin Suppression in Humans

2003 • 213 citations

Insulin, Unlike Food Intake, Does Not Suppress Ghrelin in Human Subjects

2002 • 210 citations

Plasma Ghrelin Concentrations Are Not Regulated by Glucose or Insulin

2003 • 209 citations

Marked and rapid decreases of circulating leptin in streptozotocin diabetic rats: reversal by insulin

1998 • 203 citations

Euglycemic hyperinsulinemia, but not lipid infusion, decreases circulating ghrelin levels in humans

2002 • 201 citations

Increased Hypothalamic Content of Preproneuropeptide-Y Messenger Ribonucleic Acid in Streptozotocin-Diabetic Rats*

1990 • 180 citations

Ghrelin Is Not Necessary for Adequate Hormonal Counterregulation of Insulin-Induced Hypoglycemia

2002 • 148 citations

Circulating ghrelin concentrations are lowered by intravenous glucose or hyperinsulinemic euglycemic conditions in rodents

2002 • 146 citations

Presence of Ghrelin in Normal and Adenomatous Human Pituitary

2001 • 143 citations

Effects of streptozotocin-induced diabetes and insulin treatment on the hypothalamic melanocortin system and muscle uncoupling protein 3 expression in rats.

2000 • 130 citations

Neuropeptide-Y Concentration in Microdissected Hypothalamic Regions andin VitroRelease from the Medial Basal Hypothalamus-Preoptic Area of Streptozotocin-Diabetic Rats with and without Insulin Substitution Therapy*

1990 • 128 citations

Low plasma leptin levels contribute to diabetic hyperphagia in rats.

1999 • 119 citations

Neuropeptide Y release from the paraventricular nucleus increases in association with hyperphagia in streptozotocin-induced diabetic rats.

1992 • 115 citations

Some characteristics of feeding during streptozotocin-induced diabetes in the rat.

1972 • 108 citations

Role of Ghrelin in Streptozotocin-Induced Diabetic Hyperphagia

2002 • 93 citations

Enhanced plasma ghrelin levels in rats with streptozotocin‐induced diabetes

2003 • 88 citations

Plasma leptin in diabetic and insulin-treated diabetic and normal rats

1998 • 80 citations

STZ-induced diabetes decreases and insulin normalizes POMC mRNA in arcuate nucleus and pituitary in rats

1999 • 77 citations

Neuropeptide Y Is Required for Hyperphagic Feeding in Response to Neuroglucopenia

2004 • 77 citations

Attenuation of Diabetic Hyperphagia in Neuropeptide Y–Deficient Mice

2002 • 75 citations

Nutrient inhibition of ghrelin secretion in the fasted rat

2003 • 68 citations

Post-prandial decrease of human plasma ghrelin in the absence of insulin

2003 • 37 citations

Streptozotocin-Induced Diabetes Is Associated with Reduced Immunoreactive Beta-Endorphin Concentrations in Neurointermediate Pituitary Lobe and with Disrupted Circadian Periodicity of Plasma Corticosterone Levels

1985 • 35 citations

Ghrelin in Hypothalamic Regulation of Energy Balance

2003 • 34 citations

Effects of streptozotocin-induced diabetes mellitus and insulin treatment on neuropeptide Y mRNA in the rat hypothalamus

1993 • 33 citations