Promoter Upstream Elements of the Chicken Cardiac Myosin LightChain 2-A Gene Interact with trans-Ading Regulatory Factors for Muscle-Specific Transcription

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

Purification and Biochemical Characterization of the Promoter-Specific Transcription Factor, Sp1

1986 • 1,473 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

Affinity purification of sequence-specific DNA binding proteins.

1986 • 1,255 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication

1987 • 1,050 citations

Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro

1985 • 805 citations

An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter

1985 • 763 citations

Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses.

1988 • 736 citations

Transcriptional selectivity of viral genes in mammalian cells

1986 • 722 citations

Cell-Specific Expression of the Rat Insulin Gene: Evidence for Role of Two Distinct 5′ Flanking Elements

1985 • 698 citations

A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome

1984 • 674 citations

Homologous recognition of a promoter domain common to the MSV LTR and the HSV tk gene

1986 • 562 citations

Identification of a cellular transcription factor involved in E1A trans-activation

1986 • 551 citations

A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity

1984 • 537 citations

Enhancers and eukaryotic gene transcription

1985 • 515 citations

Multiple sequence motifs are involved in SV40 enhancer function.

1986 • 511 citations

Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro

1987 • 386 citations

Myosin synthesis in cultures of differentiating chicken embryo skeletal muscle

1972 • 325 citations

The SV40 enhancer is composed of multiple functional elements that can compensate for one another

1986 • 293 citations

Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice.

1985 • 242 citations

Two distinct factors interact with the promoter regions of several liver-specific genes.

1988 • 226 citations

Tissue-specific expression is conferred by a sequence from the 5′ end of the rat albumin gene.

1984 • 202 citations

Duplicated CArG Box Domains Have Positive and Mutually Dependent Regulatory Roles in Expression of the Human α-Cardiac Actin Gene

1987 • 192 citations

Cell-specific expression of a transfected human α1-antitrypsin gene

1985 • 188 citations

A Single Polypeptide Possesses the Binding and Transcription Activities of the Adenovirus Major Late Transcription Factor

1986 • 165 citations

[30] Microinjection of tissue culture cells

1983 • 160 citations

Transcriptional Control of the Mouse Prealbumin (Transthyretin) Gene: Both Promoter Sequences and a Distinct Enhancer Are Cell Specific

1986 • 149 citations

One cell-specific and three ubiquitous nuclear proteins bind in vitro to overlapping motifs in the domain B1 of the SV40 enhancer.

1987 • 127 citations

Two nuclear factors compete for the skeletal muscle actin promoter.

1987 • 102 citations

CArG boxes in the human cardiac alpha-actin gene are core binding sites for positive trans-acting regulatory factors.

1987 • 84 citations

Expression of Bacterial β-Galactosidase in Animal Cells

1982 • 79 citations

5-Bromodeoxyuridine inhibition of differentiation. Kinetics of inhibition and reversal in myoblasts

1974 • 74 citations

Activation of a preexisting cellular factor as a basis for adenovirus E1A-mediated transcription control.

1988 • 74 citations

Multiple Regulatory Elements in the Intergenic Region Between the α-Fetoprotein and Albumin Genes

1986 • 61 citations

The promoter of the chicken cardiac myosin light chain 2 gene shows cell-specific expression in transfected primary cultures of chicken muscle

1988 • 45 citations

A factor discriminating between the wildtype and a mutant polyomavirus enhancer

1987 • 43 citations

The down-regulation of the chicken cytoplasmic β actin during myogenic differentiation does not require the gene promoter but involves the 3′ end of the gene

1988 • 23 citations

Characterization of 5'-flanking region of heart myosin light chain 2A gene. Structural and functional evidence for promoter activity.

1986 • 22 citations

What mechanisms underlie tissue-specific gene transcription?

1987 • 16 citations

Tissue-specific DNase I-hypersensitive sites and hypomethylation in the chicken cardiac myosin light chain gene (L2-A).

1987 • 11 citations

A quantitative evaluation of promoter activity by microinjection of chloramphenicol acetyltransferase hybrid genes into tissue culture cells

1988 • 5 citations

The interaction of nuclear proteins with essential promoter element of the chicken cardiac myosin light chain 2 gene is involved in muscle‐specific transcription

1988 • 4 citations

Mechanisms of control of gene expression

1988 • 2 citations