Rab4 is phosphorylated by the insulin‐activated extracellular‐signal‐regulated kinase ERK1

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii

2007 • 11,720 citations

The mitogen-activated protein kinase signal transduction pathway

1993 • 2,174 citations

Facilitative glucose transporters

1994 • 1,103 citations

Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. Apparent translocation of intracellular transport systems to the plasma membrane.

1980 • 1,066 citations

Protein kinase recognition sequence motifs

1990 • 1,014 citations

Potential mechanism of insulin action on glucose transport in the isolated rat diaphragm. Apparent translocation of intracellular transport units to the plasma membrane.

1981 • 852 citations

Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

1989 • 848 citations

The molecular machinery for secretion is conserved from yeast to neurons.

1993 • 658 citations

The small GTP-binding protein rab4 controls an early sorting event on the endocytic pathway

1992 • 648 citations

Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro.

1987 • 604 citations

Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes.

1980 • 593 citations

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

1990 • 529 citations

The Human Rab Genes Encode a Family of GTP-binding Proteins Related to Yeast YPT1 and SEC4 Products Involved in Secretion

1989 • 387 citations

Small GTP-binding protein associated with Golgi cisternae

1990 • 356 citations

Facilitative glucose transporters: an expanding family

1990 • 316 citations

Facilitative glucose transporters: regulatory mechanisms and dysregulation in diabetes.

1992 • 289 citations

The small GTP-binding protein rab4 is associated with early endosomes.

1991 • 286 citations

GTP-binding proteins in intracellular transport

1992 • 277 citations

Identification by mass spectrometry of threonine 97 in bovine myelin basic protein as a specific phosphorylation site for mitogen-activated protein kinase.

1990 • 245 citations

Co-regulation of the mitogen-activated protein kinase, extracellular signal-regulated kinase 1, and the 90-kDa ribosomal S6 kinase in PC12 cells. Distinct effects of the neurotrophic factor, nerve growth factor, and the mitogenic factor, epidermal growth factor

1993 • 224 citations

Insulin receptor signaling. Activation of multiple serine kinases.

1988 • 197 citations

Differences in the endosomal distributions of the two mannose 6-phosphate receptors.

1993 • 185 citations

Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal.

1990 • 183 citations

Inhibition of endocytic vesicle fusion in vitro by the cell-cycle control protein kinase cdc2

1989 • 167 citations

Phosphorylation of two small GTP-binding proteins of the Rab family by p34cdc2

1991 • 163 citations

Differential activation of p44mapk (ERK1) by α-thrombin and thrombin-receptor peptide agonist

1993 • 163 citations

Insulin and okadaic acid induce Rab4 redistribution in adipocytes.

1993 • 154 citations

Reversible phosphorylation--dephosphorylation determines the localization of rab4 during the cell cycle.

1992 • 149 citations

Stimulation of glucose transport and glucose transporter phosphorylation by okadaic acid in rat adipocytes.

1990 • 116 citations

Identification of small GTP-binding rab proteins in human platelets: thrombin-induced phosphorylation of rab3B, rab6, and rab8 proteins.

1993 • 110 citations

Biology of the Rap proteins, members of the ras superfamily of GTP-binding proteins

1993 • 101 citations

Cell-free fusion of endocytic vesicles is regulated by phosphorylation.

1992 • 87 citations

Differential effects of okadaic acid on insulin-stimulated glucose and amino acid uptake and phosphatidylinositol 3-kinase activity

1993 • 63 citations

Effects of okadaic acid, an inhibitor of protein phosphatases-1 and -2A, on glucose transport and metabolism in skeletal muscle

1991 • 61 citations

Nerve growth factor-induced phosphorylation cascade in PC12 pheochromocytoma cells. Association of S6 kinase II with the microtubule-associated protein kinase, ERK1.

1992 • 47 citations

Effect of cyclic AMP-dependent protein kinase on insulin receptor tyrosine kinase activity

1987 • 45 citations

Insulin stimulates a novel Mn2+-dependent cytosolic serine kinase in rat adipocytes.

1987 • 44 citations

Tyrosine and threonine phosphorylation of an immunoaffinity-purified 44-kDa MAP kinase

1991 • 32 citations

Okadaic acid stimulates IGF-II receptor translocation and inhibits insulin action in adipocytes

1993 • 12 citations