Phosphorylation of two small GTP-binding proteins of the Rab family by p34cdc2

Phase separation of integral membrane proteins in Triton X-114 solution.

1981 • 3,366 citations

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

1990 • 1,150 citations

A ras-like protein is required for a post-Golgi event in yeast secretion

1987 • 894 citations

Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+

1988 • 885 citations

The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis

1988 • 829 citations

Activation of cdc2 protein kinase during mitosis in human cells: Cell cycle-dependent phosphorylation and subunit rearrangement

1988 • 786 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast

1988 • 592 citations

The p21 ras C-terminus is required for transformation and membrane association

1984 • 590 citations

Do GTPases direct membrane traffic in secretion?

1988 • 540 citations

rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles.

1990 • 486 citations

Substrates for p34cdc2: In vivo veritas?

1990 • 472 citations

Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library.

1987 • 403 citations

The Human Rab Genes Encode a Family of GTP-binding Proteins Related to Yeast YPT1 and SEC4 Products Involved in Secretion

1989 • 387 citations

p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase.

1989 • 376 citations

Small GTP-binding protein associated with Golgi cisternae

1990 • 356 citations

Mutational analysis of SEC4 suggests a cyclical mechanism for the regulation of vesicular traffic.

1989 • 314 citations

Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2+

1988 • 314 citations

The ras-related YPT1 gene product in yeast: A GTP-binding protein that might be involved in microtubule organization

1986 • 281 citations

The GTP-binding protein Ypt1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants.

1989 • 234 citations

Acyl-CoA oxidase contains two targeting sequences each of which can mediate protein import into peroxisomes.

1988 • 196 citations

Association of the GTP-binding protein Rab3A with bovine adrenal chromaffin granules.

1990 • 195 citations

GTP-binding Ypt1 protein and Ca2+ function independently in a cell-free protein transport reaction.

1990 • 177 citations

Inhibition of endocytic vesicle fusion in vitro by the cell-cycle control protein kinase cdc2

1989 • 167 citations

Membrane traffic and organelle division

1985 • 152 citations

The ras-related mouse ypt1 protein can functionally replace the YPT1 gene product in yeast.

1989 • 136 citations

Newly synthesized G protein of vesicular stomatitis virus is not transported to the Golgi complex in mitotic cells.

1985 • 107 citations

Newly synthesized G protein of vesicular stomatitis virus is not transported to the cell surface during mitosis.

1983 • 84 citations

Characterization of highly phosphorylated subcomponents of rat thymus H1 histone.

1982 • 64 citations

Mitosis and membranes

1989 • 52 citations

Increase in the expression of a family of small guanosine triphosphate-binding proteins, rab proteins, during induced phagocyte differentiation.

1991 • 41 citations