Serial Measurement of Interleukin-6, Transforming Growth Factor-β, and S-100 Protein in Patients With Acute Stroke

Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55

1994 • 799 citations

Tumor necrosis factor-alpha expression in ischemic neurons.

1994 • 793 citations

Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta.

1993 • 789 citations

On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases

1989 • 692 citations

Inhibition of cytotoxic T cell development by transforming growth factor beta and reversal by recombinant tumor necrosis factor alpha.

1987 • 497 citations

S-100 protein and neuron-specific enolase in cerebrospinal fluid and serum: markers of cell damage in human central nervous system.

1987 • 491 citations

Inflammatory and immunomodulatory roles of TGF-β

1989 • 450 citations

P-selectin and intercellular adhesion molecule-1 expression after focal brain ischemia and reperfusion.

1994 • 428 citations

Transforming growth factor beta (TGF-?) in inflammation: A cause and a cure

1992 • 417 citations

Early Intrathecal Production of Interleukin-6 Predicts the Size of Brain Lesion in Stroke

1995 • 375 citations

Induction of Interleukin‐1β mRNA in Rat Brain After Transient Forebrain Ischemia

1992 • 336 citations

Interleukin-1 beta mRNA expression in ischemic rat cortex.

1993 • 335 citations

Proinflammatory cytokines in serum of patients with acute cerebral ischemia: kinetics of secretion and relation to the extent of brain damage and outcome of disease

1994 • 332 citations

Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat

1995 • 283 citations

Intratracheal injection of endotoxin and cytokines. II. Interleukin-6 and transforming growth factor beta inhibit acute inflammation.

1991 • 244 citations

Induction of interleukin-1β mRNA after focal cerebral ischaemia in the rat

1994 • 236 citations

Interleukin‐6 and interleukin‐1 receptor antagonist in acute stroke

1995 • 235 citations

Endothelial Adhesiveness for Blood Neutrophils Is Inhibited by Transforming Growth Factor-β

1988 • 224 citations

Cytokines and adhesion molecules in stroke and related diseases

1996 • 218 citations

Transforming growth factor-beta inhibits E-selectin expression on human endothelial cells.

1993 • 217 citations

Determination of S-100 and glial fibrillary acidic protein concentrations in cerebrospinal fluid after brain infarction.

1991 • 212 citations

Monocyte Chemoattractant Protein–1 Messenger RNA Expression in Rat Ischemic Cortex

1995 • 198 citations

TGF‐β1 is an organizer of responses to neurodgeneration

1993 • 198 citations

Expression of Interleukin-6, c-Fos, and zif268 mRNAs in Rat Ischemic Cortex

1995 • 179 citations

TGF-β1 mRNA Increases in Macrophage/Microglial Cells of the Hippocampus in Response to Deafferentation and Kainic Acid-Induced Neurodegeneration

1993 • 174 citations

Increased plasma and ventricular fluid interleukin-6 levels in patients with head injury.

1991 • 174 citations

S-100 protein and neuron-specific enolase in CSF after experimental traumatic or focal ischemic brain damage

1989 • 172 citations

Circulating Selectin- and Immunoglobulin-Type Adhesion Molecules in Acute Ischemic Stroke

1995 • 172 citations

Transforming growth factor-beta 1 (TGF-beta 1) and recombinant human tumor necrosis factor-alpha reciprocally regulate the generation of lymphokine-activated killer cell activity. Comparison between natural porcine platelet-derived TGF-beta 1 and TGF-beta 2, and recombinant human TGF-beta 1.

1988 • 168 citations

The Biology of Interleukin-6

2015 • 154 citations

Glial cell-specific mechanisms of TGF-β1 induction by IL-1 in cerebral cortex

1993 • 142 citations

Upregulation of intercellular adhesion molecule 1 (ICAM-1) on brain microvascular endothelial cells in rat ischemic cortex

1994 • 136 citations

Cytokine-induced neutrophil chemoattractant mRNA expressed in cerebral ischemia

1993 • 114 citations

Serum creatinine: an independent predictor of survival after stroke

1991 • 109 citations

Assessment of damage to the central nervous system by determination of S-100 protein in the cerebrospinal fluid.

1982 • 106 citations

Demonstration of Increased Endothelial-Leukocyte Adhesion Molecule–1 mRNA Expression in Rat Ischemic Cortex

1995 • 99 citations

Autocrine and paracrine regulation of astrocyte function by transforming growth factor-β

1992 • 96 citations

Peripheral white blood cell count in cerebral ischemic infarction

2009 • 78 citations

The Biology of Interleukin-6 (Part 1 of 2)

1992 • 74 citations

Adhesive glycoproteins CD11a and CD18 are upregulated in the leukocytes from patients with ischemic stroke and transient ischemic attacks

1995 • 62 citations

Prognosis in acute stroke with special reference to some cardiac factors

1983 • 54 citations

Decreased serum levels of TGF-? in patients with acutePlasmodium falciparum malaria

1995 • 53 citations

Interleukin‐6 production in “normal” and HTLV‐1 tax‐expressing brain‐specific endothelial cells

1993 • 30 citations

Peripheral and central regulation of IL-6 gene expression in endotoxin-treated rats.

1992 • 14 citations

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