Diagnosis of extrapulmonary tuberculosis by PCR

Global Tuberculosis Control 2011, WHO Report 2011

2012 • 1,054 citations

Epidemiology of Extrapulmonary Tuberculosis in the United States, 1993–2006

2009 • 689 citations

Intraocular Tuberculosis—An Update

2007 • 642 citations

Extra Pulmonary Tuberculosis: An Overview

2019 • 493 citations

Extrapulmonary tuberculosis: an overview

2015 • 479 citations

Update on tuberculous pleural effusion

2010 • 422 citations

Rapid Molecular Detection of Extrapulmonary Tuberculosis by the Automated GeneXpert MTB/RIF System

2011 • 409 citations

Miliary tuberculosis: new insights into an old disease

2005 • 397 citations

Dominant TNF-α+ Mycobacterium tuberculosis–specific CD4+ T cell responses discriminate between latent infection and active disease

2011 • 372 citations

Xpert MTB/RIF: a New Pillar in Diagnosis of Extrapulmonary Tuberculosis?

2011 • 344 citations

Clinical validation of Xpert MTB/RIF for the diagnosis of extrapulmonary tuberculosis

2012 • 312 citations

Diagnosis of Extrapulmonary Tuberculosis by Smear, Culture, and PCR Using Universal Sample Processing Technology

2005 • 272 citations

Commercial Serological Tests for the Diagnosis of Active Pulmonary and Extrapulmonary Tuberculosis: An Updated Systematic Review and Meta-Analysis

2011 • 255 citations

Differentiating Intestinal Tuberculosis From Crohn's Disease: A Diagnostic Challenge

2009 • 249 citations

Cutaneous tuberculosis

2007 • 246 citations

Nucleic acid amplification tests in the diagnosis of tuberculous pleuritis: a systematic review and meta-analysis

2004 • 243 citations

Evaluation of Polymerase Chain Reaction, Adenosine Deaminase, and Interferon-γ in Pleural Fluid for the Differential Diagnosis of Pleural Tuberculosis

2000 • 189 citations

Advances in the diagnosis of tuberculosis

2010 • 174 citations

Rapid Diagnosis of Extrapulmonary Tuberculosis by PCR: Impact of Sample Preparation and DNA Extraction

2003 • 167 citations

Improved diagnostic value of PCR in the diagnosis of female genital tuberculosis leading to infertility

2005 • 156 citations

Nanobead-based interventions for the treatment and prevention of tuberculosis

2010 • 154 citations

Comparison of Two Molecular Methods for Rapid Diagnosis of Extrapulmonary Tuberculosis

2011 • 144 citations

Real-Time PCR Assay Using Fine-Needle Aspirates and Tissue Biopsy Specimens for Rapid Diagnosis of Mycobacterial Lymphadenitis in Children

2004 • 142 citations

Polymerase chain reaction in clinically suspected genitourinary tuberculosis: comparison with intravenous urography, bladder biopsy, and urine acid fast bacilli culture

2000 • 136 citations

The Use of Adenosine Deaminase and Interferon-γ as Diagnostic Tools for Tuberculous Pericarditis

2002 • 133 citations

Molecular diagnostics in tuberculosis

2005 • 133 citations

Ocular Tuberculosis: A Clinicopathologic and Molecular Study

2010 • 131 citations

Newer diagnostic techniques for tuberculosis.

2004 • 130 citations

Polymerase chain reaction for detection of Mycobacterium tuberculosis in epiretinal membrane in Eales' disease.

2000 • 127 citations

Etiology and management of genitourinary tuberculosis

2011 • 127 citations

Identification of the Causative Organism of Tuberculous Lymphadenitis in Ethiopia by PCR

2002 • 126 citations

Clinical evaluation of the polymerase chain reaction for the rapid diagnosis of tuberculosis

2004 • 126 citations

Differentiation between intestinal tuberculosis and Crohn's disease in endoscopic biopsy specimens by polymerase chain reaction

2002 • 122 citations

Rapid diagnosis of tuberculosis through the detection of mycobacterial DNA in urine by nucleic acid amplification methods

2009 • 117 citations

Immuno-PCR: a promising ultrasensitive diagnostic method to detect antigens and antibodies

2011 • 115 citations

Ocular tuberculosis: diagnostic and treatment challenges

2009 • 105 citations

RAPID DIAGNOSIS OF GENITOURINARY TUBERCULOSIS BY POLYMERASE CHAIN REACTION AND NON-RADIOACTIVE DNA HYBRIDIZATION

2000 • 104 citations

Tuberculosis of the Thyroid Gland: Review of the Literature

2006 • 104 citations

Polymerase Chain Reaction Detection of Mycobacterium tuberculosis From Fine‐Needle Aspirate for the Diagnosis of Cervical Tuberculous Lymphadenitis

2000 • 102 citations

Tuberculous lymphadenitis.

2009 • 99 citations

Novel Multipurpose Methodology for Detection of Mycobacteria in Pulmonary and Extrapulmonary Specimens by Smear Microscopy, Culture, and PCR

2005 • 92 citations

Diagnosis of tuberculous aetiology in pericardial effusions

2004 • 90 citations

Evaluating PCR, culture & histopathology in the diagnosis of female genital tuberculosis.

2011 • 87 citations

New Diagnostics for Latent and Active Tuberculosis: State of the Art and Future Prospects

2008 • 87 citations

Tuberculosis of the breast

2008 • 84 citations

Combined Use of the Polymerase Chain Reaction and Detection of Adenosine Deaminase Activity on Pleural Fluid Improves the Rate of Diagnosis of Pleural Tuberculosis

2003 • 80 citations

Male genital tuberculosis

2008 • 80 citations

Novel Technique of Quantitative Nested Real-Time PCR Assay for Mycobacterium tuberculosis DNA

2006 • 80 citations

In Situ PCR forMycobacterium tuberculosisin Endoscopic Mucosal Biopsy Specimens of Intestinal Tuberculosis and Crohn Disease

2008 • 78 citations

Multiplex PCR for rapid diagnosis of tuberculous meningitis

2011 • 76 citations

Assessment of possible tuberculous lymphadenopathy by PCR compared to non-molecular methods

2005 • 76 citations

Efficient diagnosis of tuberculous meningitis by detection of Mycobacterium tuberculosis DNA in cerebrospinal fluid filtrates using PCR

2009 • 74 citations

Histopathology and TB-PCR kit analysis in differentiating the diagnosis of intestinal tuberculosis and Crohn’s disease

2010 • 73 citations

Blood and urine samples as useful sources for the direct detection of tuberculosis by polymerase chain reaction

2006 • 73 citations

Diagnosis and follow-up of treatment of latent tuberculosis; the utility of the QuantiFERON-TB Gold In-tube assay in outpatients from a tuberculosis low-endemic country

2010 • 73 citations

The role of polymerase chain reaction in the management of osteoarticular tuberculosis

2007 • 70 citations

Performance of Xpert MTB/RIF RUO Assay and IS 6110 Real-Time PCR for Mycobacterium tuberculosis Detection in Clinical Samples

2011 • 69 citations

PCR-based detection of the Mycobacterium tuberculosis complex in urine of HIV-infected and uninfected pulmonary and extrapulmonary tuberculosis patients in Burkina Faso

2004 • 69 citations

Improved laboratory diagnosis of tuberculosis – The Indian experience

2011 • 67 citations

Polymerase chain reaction compared to other laboratory findings and to clinical evaluation in the diagnosis of cutaneous tuberculosis and atypical mycobacteria skin infection

2008 • 65 citations

WHO recommends against inaccurate tuberculosis tests

2011 • 65 citations

Cutaneous tuberculosis in children: The Indian perspective

2010 • 64 citations

Nucleic acid amplification tests for the diagnosis of tuberculous lymphadenitis: a systematic review.

2007 • 64 citations

Evaluation of Reverse Transcription-PCR and a Bacteriophage-Based Assay for Rapid Phenotypic Detection of Rifampin Resistance in Clinical Isolates of Mycobacterium tuberculosis

1999 • 63 citations

Evaluation of clinico-radiological, bacteriological, serological, molecular and histological diagnosis of osteoarticular tuberculosis

2008 • 63 citations

Comparison of PCR with standard culture of fine needle aspiration samples in the diagnosis of tuberculosis lymphadenitis

2011 • 60 citations

Role of the Clinical Mycobacteriology Laboratory in Diagnosis and Management of Tuberculosis in Low-Prevalence Settings

2010 • 59 citations

Early Diagnosis of Extrapulmonary Tuberculosis by a New Procedure Combining Broth Culture and PCR

2009 • 58 citations

PCR for M. tuberculosis in tissue samples

2009 • 58 citations

The Clinical Utility of Polymerase Chain Reaction for the Diagnosis of Pleural Tuberculosis

2005 • 53 citations

Rapid diagnosis of tuberculous meningitis: A comparative evaluation of in-house PCR assays involving three mycobacterial DNA sequences, IS6110, MPB-64 and 65 kDa antigen

2006 • 50 citations

Extrapulmonary tuberculosis: tuberculous meningitis new developments.

2011 • 50 citations

Removal of PCR Inhibitors by Silica Membranes: Evaluating the Amplicor Mycobacterium tuberculosis Kit

2001 • 49 citations

Pleural fluid interferon‐γ and adenosine deaminase levels in tuberculosis pleural effusion: a cost‐effectiveness analysis

2005 • 47 citations

Comparative Evaluation of Early Diagnosis of Tuberculous Meningitis by Different Assays

2006 • 47 citations

DIAGNOSTIC VALUE OF DIFFERENT PCR ASSAYS FOR THE DETECTION OF MYCOBACTERIAL DNA IN GRANULOMATOUS LYMPHADENOPATHY

1996 • 46 citations

Primary tuberculosis of thyroid gland: a rare case report

2007 • 44 citations

Intraocular Tuberculosis

2010 • 44 citations

Polymerase chain reaction for the detection of Mycobacterium tuberculosis in synovial fluid, tissue samples, bone marrow aspirate and peripheral blood.

2003 • 44 citations

Multiplex Real-Time Polymerase Chain Reaction

2010 • 44 citations

Fecal polymerase chain reaction for Mycobacterium tuberculosis IS6110 to distinguish Crohn’s disease from intestinal tuberculosis

2010 • 43 citations

Evaluation of an in-house-developed PCR for the diagnosis of tuberculous meningitis in Indian children

2005 • 42 citations

Does multiplex Polymerase Chain Reaction increase the diagnostic percentage in osteoarticular tuberculosis? A prospective evaluation of 80 cases

2011 • 42 citations

Evolutionary Relationships among Strains of Mycobacterium tuberculosis with Few Copies of IS 6110

2003 • 41 citations

Real-time Quantitative PCR in the Diagnosis of Tuberculosis in Formalin-fixed Paraffin-embedded Pleural Tissue in Patients From a High HIV Endemic Area

2008 • 39 citations

Osteoarticular tuberculosis – diagnostic solutions in a disease endemic region

2009 • 38 citations

Further investigations on the association of Mycobacterium tuberculosis with Eales' disease.

2002 • 37 citations

Novel Wide-Range Quantitative Nested Real-Time PCR Assay for Mycobacterium tuberculosis DNA: Clinical Application for Diagnosis of Tuberculous Meningitis

2008 • 36 citations

Development of an ultrasensitive polymerase chain reaction–amplified immunoassay based on mycobacterial RD antigens: implications for the serodiagnosis of tuberculosis

2012 • 36 citations

Nested-PCR using MPB64 fragment improves the diagnosis of pleural and meningeal tuberculosis

2000 • 36 citations

COMPARISON OF VARIOUS MICROBIOLOGICAL TESTS INCLUDING POLYMERASE CHAIN REACTION FOR THE DIAGNOSIS OF OSTEOARTICULAR TUBERCULOSIS

2005 • 35 citations

Evaluation of polymerase chain reaction using protein b primers for rapid diagnosis of tuberculous meningitis

2010 • 35 citations

Clinical Utility of Polymerase Chain Reaction for Diagnosis of Smear-negative Pleural Tuberculosis

2007 • 35 citations

UTILITY OF POLYMERASE CHAIN REACTION IN DIAGNOSIS OF TUBERCULOSIS FROM SAMPLES OF BONE MARROW ASPIRATE

2006 • 34 citations

Use of polymerase chain reaction in the diagnosis of abdominal tuberculosis

2006 • 33 citations

Highly Accurate Diagnosis of Pleural Tuberculosis by Immunological Analysis of the Pleural Effusion

2012 • 33 citations

Evaluation of real-time PCR of patient pleural effusion for diagnosis of tuberculosis

2011 • 33 citations

DIAGNOSIS OF TUBERCULOSIS LYMPHADENITIS USING A POLYMERASE CHAIN REACTION ON PERIPHERAL BLOOD MONONUCLEAR CELLS

2003 • 33 citations

Utility of a combination of RD1 and RD2 antigens as a diagnostic marker for tuberculosis

2009 • 31 citations

Tuberculosis of the breast with erythema nodosum: a case report

2010 • 31 citations

Evaluation of real-time polymerase chain reaction, interferon-gamma, adenosine deaminase, and immunoglobulin A for the efficient diagnosis of pleural tuberculosis

2011 • 31 citations

Utility of the polymerase chain reaction in the diagnosis of tuberculous meningitis

2006 • 30 citations

Utility of reverse transcriptase PCR and DNA-PCR in the diagnosis of female genital tuberculosis

2010 • 30 citations

Evaluation of the polymerase chain reaction in the diagnosis of miliary tuberculosis in bone marrow smear.

2003 • 29 citations

Detection and Identification of Mycobacterium tuberculosis in Joint Biopsy Specimens by rpoB PCR Cloning and Sequencing

2005 • 29 citations

Utility of polymerase chain reaction as a diagnostic tool in cutaneous tuberculosis.

2007 • 28 citations

Clinical Evaluation of a 16S Ribosomal RNA Polymerase Chain Reaction Test for the Diagnosis of Lymph Node Tuberculosis

2006 • 26 citations

Application of the polymerase chain reaction on formalin-fixed, paraffin-embedded tissue in the recognition of tuberculous osteomyelitis

2006 • 26 citations

Diagnosis of tubercular uveitis by quantitative polymerase chain reaction

2010 • 23 citations

Adenosine deaminase estimation and multiplex polymerase chain reaction in diagnosis of extra-pulmonary tuberculosis.

2008 • 23 citations

Comparative study of PCR, smear examination and culture for diagnosis of cutaneous tuberculosis.

2005 • 22 citations

Multiplex PCR-Identified Cutaneous Tuberculosis Evoked by Mycobacterium bovis BCG Vaccination in a Healthy Baby

2005 • 21 citations

Clinical value of polymerase chain reaction in the diagnosis of joint tuberculosis by detecting the DNA ofMycobacterium tuberculosis

2011 • 21 citations

Constrictive pericarditis: Detection of mycobacterium tuberculosis in paraffin-embedded pericardial tissues by polymerase chain reaction

2007 • 20 citations

Urinary tuberculosis: Modern issues

2009 • 20 citations

PCR in the diagnosis of cutaneous tuberculosis

2003 • 20 citations

PCR detection ofMycobacterium tuberculosisin necrotising non-granulomatous lymphadenitis using formalin-fixed paraffin-embedded tissue: a study in Thai patients

2009 • 20 citations

Comparison of methods of DNA extraction for real‐time PCR in a model of pleural tuberculosis

2009 • 19 citations

A Case of Tuberculosis Cutis Orificialis with Perianal Involvement

2009 • 18 citations

Polymerase chain reaction as a useful and simple tool for rapid diagnosis of tuberculous meningitis in a Brazilian tertiary care hospital

2008 • 18 citations

Identification of a repetitive sequence belonging to a PPE gene of Mycobacterium tuberculosis and its use in diagnosis of tuberculosis

2006 • 15 citations

Clinical usefulness of the nested polymerase chain reaction in the diagnosis of extrapulmonary tuberculosis

2009 • 15 citations

Diagnosis of osteoarticular tuberculosis

2011 • 14 citations

Improved detection and differentiation of mycobacteria with combination of Mycobacterium Growth Indicator Tube and Roche COBAS AMPLICOR System in conjunction with Duplex PCR

2001 • 14 citations

HIV-associated tuberculous lymphadenitis: the importance of polymerase chain reaction (PCR) as a complementary tool for the diagnosis of tuberculosis - a study of 104 patients

2011 • 13 citations

Efficacy of an in-house polymerase chain reaction assay for rapid diagnosis of Mycobacterium tuberculosis in patients with tubercular lymphadenitis: Comparison with fine needle aspiration cytology and conventional techniques

2010 • 12 citations

Evaluation of polymerase chain reaction (PCR) using hupB gene in diagnosis of tuberculous lymphadenitis in fine needle aspirates.

2010 • 10 citations

Rapid diagnosis in early stage renal tuberculosis by real-time polymerase chain reaction on renal biopsy specimens.

2010 • 9 citations

Tuberculosis diagnosed by PCR analysis of synovial fluid

2010 • 8 citations

Detection of Mycobacterium tuberculosis complex DNA in pericardial fluid, bone marrow and peripheral blood in a patient with pericardial tuberculosis A case report

2001 • 7 citations

Clinical Utility of Polymerase Chain Reaction for the Diagnosis of Smear-negative Pleural Tuberculosis

2007 • 6 citations

Diagnostic tests for tuberculous lymphadenitis: fine needle aspirations using tissue culture in mycobacteria growth indicator tube and tissue PCR

2010 • 6 citations

Detection of Mycobacterium tuberculosis in corneas from donors with active tuberculosis disease through polymerase chain reaction and culture

2009 • 5 citations

Abdominal Tuberculosis

2010 • 4 citations

Diagnostic usefulness of bone marrow aspiration material for the amplification of IS6110 insertion element in extrapulmonary tuberculosis: comparison of two PCR techniques.

2005 • 4 citations

Nucleic acid amplification for detection of Mycobacterium tuberculosis

2009 • 2 citations

DEVELOPMENT OF A TB-PCR KIT FOR THE DIAGNOSIS OF TUBERCULOSIS

2011 • 2 citations