Immuno-PCR: a promising ultrasensitive diagnostic method to detect antigens and antibodies

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications

2004 • 6,403 citations

Nanoparticle-Based Bio-Barcodes for the Ultrasensitive Detection of Proteins*

2020 • 2,036 citations

Enzyme Immunoassay (EIA)/Enzyme-Linked Immunosorbent Assay (ELISA)

2005 • 1,392 citations

Immuno-PCR: Very Sensitive Antigen Detection by Means of Specific Antibody-DNA Conjugates

1992 • 815 citations

Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. 1985.

1992 • 740 citations

Immunoassays with rolling circle DNA amplification: A versatile platform for ultrasensitive antigen detection

2000 • 581 citations

Hepatitis B Virus DNA in Patients with Chronic Liver Disease and Negative Tests for Hepatitis B Surface Antigen

1985 • 466 citations

Immuno-PCR: high sensitivity detection of proteins by nucleic acid amplification

2005 • 312 citations

Chronic type B hepatitis and the “healthy” Hbsag carrier state

1987 • 295 citations

Bio-Barcodes Based on Oligonucleotide-Modified Nanoparticles

2002 • 236 citations

Self-assembly of DNA-streptavidin nanostructures and their use as reagents in immuno-PCR

1999 • 210 citations

Detecting antigens by quantitative immuno-PCR

2007 • 165 citations

Lowering the Detection Limits of HIV-1 Viral Load Using Real-Time Immuno-PCR for HIV-1 p24 Antigen

2004 • 134 citations

Sensitivity by combination: immuno-PCR and related technologies

2008 • 133 citations

Lowering the Detection Limits of HIV-1 Viral Load Using Real-Time Immuno-PCR for HIV-1 p24 Antigen

2004 • 128 citations

Universal immuno-PCR for ultra-sensitive target proteindetection

1993 • 110 citations

A highly sensitive immuno-polymerase chain reaction assay for Clostridium botulinum neurotoxin type A

2003 • 108 citations

Magneto Immuno-PCR: A novel immunoassay based on biogenic magnetosome nanoparticles

2007 • 98 citations

Supramolecular Nanocircles Consisting of Streptavidin and DNA

2000 • 95 citations

Synthesis of protein–nucleic acid conjugates by expressed protein ligation

2003 • 88 citations

Gold nanoparticle enhanced immuno-PCR for ultrasensitive detection of Hantaan virus nucleocapsid protein

2009 • 81 citations

Phage display mediated immuno-PCR

2006 • 77 citations

New Immuno-PCR Assay for Detection of Low Concentrations of Shiga Toxin 2 and Its Variants

2008 • 75 citations

A quantitative real-time immuno-PCR approach for detection of staphylococcal enterotoxins

2007 • 73 citations

Detection of respiratory syncytial virus using nanoparticle amplified immuno-polymerase chain reaction

2010 • 68 citations

Development of a two-site immuno-PCR assay for hepatitis B surface antigen

1995 • 59 citations

Immuno-PCR for Detection of Antigen to Angiostrongylus cantonensis Circulating Fifth-Stage Worms

2004 • 59 citations

A highly sensitive immuno-PCR assay for detecting Group A Streptococcus

2003 • 59 citations

Immunomagnetic quantitative immuno-PCR for detection of less than one HIV-1 virion

2009 • 57 citations

Immunopolymerase Chain Reaction Using Real-Time Polymerase Chain Reaction for Detection

2000 • 56 citations

Detection of Rotavirus from stool samples using a standardized immuno-PCR (“Imperacer”) method with end-point and real-time detection

2005 • 56 citations

Detection of ultra-low levels of pathologic prion protein in scrapie infected hamster brain homogenates using real-time immuno-PCR

2005 • 55 citations

Development of a quantitative immuno-PCR assay and its use to detect mumps-specific IgG in serum

2002 • 55 citations

Diagnostic methods

2002 • 51 citations

Applications of real-time immuno-polymerase chain reaction (rt-IPCR) for the rapid diagnoses of viral antigens and pathologic proteins

2006 • 48 citations

Site-specific conjugation of oligonucleotides to the C-terminus of recombinant protein by expressed protein ligation

2004 • 48 citations

Development of immuno-PCR for diagnosis of bovine herpesvirus 1 infection

1996 • 47 citations

A quantitative immuno-PCR assay for the detection of mumps-specific IgG

2002 • 47 citations

Detection of norovirus capsid proteins in faecal and food samples by a real time immuno-PCR method

2006 • 44 citations

Nanostructured DNA−Protein Aggregates Consisting of Covalent Oligonucleotide−Streptavidin Conjugates

2001 • 44 citations

An immuno-PCR method for detecting Bacillus thuringiensis Cry1Ac toxin

2005 • 42 citations

Detection of bacterial antigens using immuno-PCR

1996 • 39 citations

Use of HIV-1 p24 as a sensitive, precise and inexpensive marker for infection, disease progression and treatment failure

2000 • 38 citations

Expression Immunoassay. Antigen Quantitation Using Antibodies Labeled with Enzyme-Coding DNA Fragments

1995 • 37 citations

Immunoquantitative PCR for Prion Protein Detection in Sporadic Creutzfeldt–Jakob Disease

2005 • 34 citations

A modified immuno-polymerase chain reaction for the detection of β-glucuronidase from Escherichia coli

1997 • 32 citations

Ultrasensitive detection of antibodies using a new Tus–Ter-lock immunoPCR system

2010 • 30 citations

Immuno‐Quantitative Polymerase Chain Reaction for Detection and Quantitation of Prion Protein

2004 • 28 citations

A highly sensitive immuno-PCR assay for detection of H5N1 avian influenza virus

2010 • 27 citations

Detection of Staphylococcus aureus by a Sensitive Immuno-PCR Assay

2004 • 25 citations

Supramolecular DNA-Streptavidin Nanocircles with a Covalently Attached Oligonucleotide Moiety

2002 • 23 citations

Response : Immuno-PCR with a Commercially Available Avidin System

1993 • 17 citations

A rapid and highly sensitive method for diagnosis of equine influenza by antigen detection using immuno-PCR.

2001 • 15 citations

Identification ofBacteroides fragilisby a modified Immuno Polymerase Chain Reaction (mIPCR), using a specific monoclonal antibody

1998 • 7 citations

Immuno-polymerase chain reaction as a unique molecular tool for detection of infectious agents

2007 • 5 citations