Rapid diagnosis of tuberculosis through the detection of mycobacterial DNA in urine by nucleic acid amplification methods

Presence of fetal DNA in maternal plasma and serum

1997 • 2,884 citations

Quantitative Analysis of Fetal DNA in Maternal Plasma and Serum: Implications for Noninvasive Prenatal Diagnosis

1998 • 1,629 citations

Paediatric tuberculosis

2008 • 457 citations

Tuberculosis in sub-Saharan Africa: opportunities, challenges, and change in the era of antiretroviral treatment

2006 • 447 citations

Genetic Analysis of DNA Excreted in Urine: A New Approach for Detecting Specific Genomic DNA Sequences from Cells Dying in an Organism

2000 • 363 citations

Operational Feasibility of Using Loop-Mediated Isothermal Amplification for Diagnosis of Pulmonary Tuberculosis in Microscopy Centers of Developing Countries

2007 • 334 citations

Prediction of fetal D status from maternal plasma: introduction of a new noninvasive fetal RHD genotyping service

2002 • 331 citations

Direct Molecular Detection of Nucleic Acids by Fluorescence Signal Amplification

2005 • 263 citations

Size Separation of Circulatory DNA in Maternal Plasma Permits Ready Detection of Fetal DNA Polymorphisms

2004 • 246 citations

Human Urine Contains Small, 150 to 250 Nucleotide-Sized, Soluble DNA Derived from the Circulation and May Be Useful in the Detection of Colorectal Cancer

2004 • 226 citations

Advances in the Diagnosis and Treatment of Tuberculosis

2006 • 214 citations

Delay in Diagnosis among Hospitalized Patients with Active Tuberculosis—Predictors and Outcomes

2002 • 192 citations

Human Immunodeficiency Virus and the Prevalence of Undiagnosed Tuberculosis in African Gold Miners

2004 • 183 citations

In-house nucleic acid amplification tests for the detection of Mycobacterium tuberculosis in sputum specimens: meta-analysis and meta-regression

2005 • 183 citations

Disseminated Tuberculosis

2007 • 143 citations

The role of IS6110 in the evolution of Mycobacterium tuberculosis

2007 • 128 citations

Transrenal Nucleic Acids: From Proof of Principle to Clinical Tests

2008 • 106 citations

RAPID DIAGNOSIS OF GENITOURINARY TUBERCULOSIS BY POLYMERASE CHAIN REACTION AND NON-RADIOACTIVE DNA HYBRIDIZATION

2000 • 104 citations

The Usefulness of the Detection of GSTP1 Methylation in Urine as a Biomarker in the Diagnosis of Prostate Cancer

2008 • 104 citations

Demonstration of homology between IS6110 of Mycobacterium tuberculosis and DNAs of other Mycobacterium spp.?

1995 • 101 citations

Development of an Internal Positive Control for Rapid Diagnosis of Avian Influenza Virus Infections by Real-Time Reverse Transcription-PCR with Lyophilized Reagents

2006 • 96 citations

Mycobacterium tuberculosis DNA detection in soluble fraction of urine from pulmonary tuberculosis patients.

2008 • 90 citations

Multiplex Tandem PCR: a Novel Platform for Rapid Detection and Identification of Fungal Pathogens from Blood Culture Specimens

2008 • 90 citations

Isolation and Comparative Study of Cell‐Free Nucleic Acids from Human Urine

2006 • 85 citations

The potential impact of enhanced diagnostic techniques for tuberculosis driven by HIV: a mathematical model

2006 • 84 citations

Diagnosis of Pulmonary Tuberculosis Using PCR Assays on Sputum Collected within 24 Hours of Hospital Admission

1998 • 76 citations

Mailed, Home-Obtained Urine Specimens: a Reliable Screening Approach for Detecting Asymptomatic Chlamydia trachomatis Infections

1999 • 74 citations

Blood and urine samples as useful sources for the direct detection of tuberculosis by polymerase chain reaction

2006 • 73 citations

PCR-based detection of the Mycobacterium tuberculosis complex in urine of HIV-infected and uninfected pulmonary and extrapulmonary tuberculosis patients in Burkina Faso

2004 • 69 citations

Optimization of Transrenal DNA Analysis: Detection of Fetal DNA in Maternal Urine

2009 • 69 citations

High incidence of tuberculosis in renal patients

1990 • 63 citations

Improvement in fetal DNA extraction from maternal plasma. Evaluation of the NucliSens Magnetic Extraction system and the QIAamp DSP Virus Kit in comparison with the QIAamp DNA Blood Mini Kit

2006 • 63 citations

Spread of an emerging Mycobacterium tuberculosis drug-resistant strain in the western Cape of South Africa.

2007 • 61 citations

PCR Amplification of the IS 6110 Insertion Element of Mycobacterium tuberculosis in Fecal Samples from Patients with Intestinal Tuberculosis

2006 • 61 citations

A urine-based polymerase chain reaction method for the diagnosis of visceral leishmaniasis in immunocompetent patients

2007 • 58 citations

Transrenal DNA testing: progress and perspectives

2006 • 55 citations

Sputum microscopy for the diagnosis of HIV-associated pulmonary tuberculosis in Tanzania

2008 • 50 citations

Agreement between clinical scoring systems used for the diagnosis of pediatric tuberculosis in the HIV era.

2007 • 50 citations

Evaluation of PCR-based methods for the diagnosis of tuberculosis by identification of mycobacterial DNA in urine samples.

2002 • 49 citations

Improved DNA typing of human urine by adding EDTA

1999 • 48 citations

Utility of nucleic acid amplification techniques for the diagnosis of pulmonary tuberculosis in sub-Saharan Africa.

2001 • 46 citations

Detection ofMycobacterium tuberculosisby PCR analysis of urine and other clinical samples from AIDS and non-HIV-infected patients

1997 • 45 citations

Diagnosis of Pediatric Pulmonary Tuberculosis by Stool PCR

2008 • 45 citations

Tuberculosis: amplification-based clinical diagnostic techniques

2003 • 42 citations

Genotyping for DQA1 and PM loci in urine using PCR-based amplification: Effects of sample volume, storage temperature, preservatives, and aging on DNA extraction and typing

1999 • 40 citations

Identification of HIV patients with active pulmonary tuberculosis using urine based polymerase chain reaction assay

1999 • 38 citations

Urine as an adjunct specimen for the diagnosis of active pulmonary tuberculosis

2008 • 38 citations

Polymerase chain reaction for detection ofMycobacterium tuberculosis in sputum

1993 • 37 citations

DNA extraction from human urinary sediment

1998 • 34 citations

DNA extraction from human urinary sediment.

1998 • 32 citations

Presence of Donor-Derived DNA and Cells in the Urine of Sex-Mismatched Hematopoietic Stem Cell Transplant Recipients: Implication for the Transrenal Hypothesis

2008 • 29 citations

Urinary Thymidine Dimer as a Marker of Total Body Burden of UV-Inflicted DNA Damage in Humans

2005 • 26 citations

Stability of Trichomonas vaginalis DNA in Urine Specimens

2008 • 20 citations

Analysis of urinary donor-derived DNA in renal transplant recipients with acute rejection

2002 • 18 citations

Nucleic acid detection and quantification in the developing world

2009 • 18 citations

Comparison of polymerase chain reaction for IS6110 and Amplicor in the diagnosis of tuberculosis.

1996 • 16 citations

Comparison of amplicor and 32-kilodalton PCR for detection of Mycobacterium tuberculosis from sputum specimens

1996 • 14 citations

Bacillarity at autopsy in pulmonary tuberculosis

2002 • 10 citations

Urinary DNA as an indicator of nephrotoxicity caused by endotoxin and gentamicin in mice

1994 • 5 citations