Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Molecular basis of agonism and antagonism in the oestrogen receptor

1997 • 3,285 citations

Automated MAD and MIR structure solution

1999 • 3,079 citations

Nuclear Receptors and Lipid Physiology: Opening the X-Files

2001 • 2,040 citations

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods

1997 • 1,905 citations

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

1998 • 1,902 citations

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

1995 • 1,085 citations

Dopamine Neuron Agenesis in Nurr1-Deficient Mice

1997 • 1,075 citations

Structure and specificity of nuclear receptor–coactivator interactions

1998 • 922 citations

The nuclear receptor ligand-binding domain: structure and function

1998 • 829 citations

Orphan Nuclear Receptors: From Gene to Function*

1999 • 789 citations

Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons

1998 • 725 citations

Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor

1997 • 543 citations

Superconducting Single Crystals of Tl2Ba2CaCu2O8 and YBa2Cu4O8: Crystal Structures in the Vicinity of Tc

1998 • 543 citations

Orphan Nuclear Receptors: Shifting Endocrinology into Reverse

1999 • 498 citations

Mutations in NR4A2 associated with familial Parkinson disease

2002 • 478 citations

Ligand binding was acquired during evolution of nuclear receptors

1997 • 407 citations

Identification of a new brain-specific transcription factor, NURR1.

1992 • 373 citations

Hepatocyte Nuclear Factor 4 Is a Transcription Factor that Constitutively Binds Fatty Acids

2002 • 297 citations

Structural and Functional Evidence for Ligand-Independent Transcriptional Activation by the Estrogen-Related Receptor 3

2002 • 278 citations

Crystal Structure of the HNF4α Ligand Binding Domain in Complex with Endogenous Fatty Acid Ligand

2002 • 270 citations

The NGFI-B subfamily of the nuclear receptor superfamily (review).

1998 • 145 citations

Dynamic Stabilization of Nuclear Receptor Ligand Binding Domains by Hormone or Corepressor Binding

2000 • 108 citations

Phosphorylation and Intramolecular Stabilization of the Ligand Binding Domain in the Nuclear Receptor Steroidogenic Factor 1

2002 • 107 citations

Defining Requirements for Heterodimerization between the Retinoid X Receptor and the Orphan Nuclear Receptor Nurr1

2002 • 83 citations

Activity of the Nurr1 Carboxyl-terminal Domain Depends on Cell Type and Integrity of the Activation Function 2

1999 • 76 citations

Structure-Function Analysis of the Rev-erbA and RVR Ligand-Binding Domains Reveals a Large Hydrophobic Surface That Mediates Corepressor Binding and a Ligand Cavity Occupied by Side Chains

2000 • 61 citations