Cytochrome P450 1B1: a major P450 isoenzyme in human blood monocytes and macrophage subsets

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

The colorimetric estimation of formaldehyde by means of the Hantzsch reaction

1953 • 4,357 citations

High gradient magnetic cell separation with MACS

1990 • 1,648 citations

Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.

1996 • 793 citations

Identification of three different truncating mutations in cytochrome P4501B1 (CYP1B1) as the principal cause of primary congenital glaucoma (Buphthalmos) in families linked to the GLC3A locus on chromosome 2p21

1997 • 630 citations

MOLECULAR MECHANISMS OF GENETIC POLYMORPHISMS OF DRUG METABOLISM

1997 • 540 citations

Tumor-specific expression of cytochrome P450 CYP1B1.

1997 • 527 citations

Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2.

1994 • 503 citations

Pretreatment of plastic petri dishes with fetal calf serum. A simple method for macrophage isolation

1979 • 498 citations

Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a.

1986 • 341 citations

Two calcium-binding proteins associated with specific stages of myeloid cell differentiation are expressed by subsets of macrophages in inflammatory tissues.

1988 • 277 citations

Radioactive assay for aryl hydrocarbon hydroxylase. Improved method and biological importance

1977 • 265 citations

A Monoclonal Antibody to a Novel Differentiation Antigen on Human Macrophages Associated with the Down-Regulatory Phase of the Inflammatory Process

1987 • 240 citations

A monoclonal antibody to a differentiation antigen present on mature human macrophages and absent from monocytes.

1985 • 238 citations

Isolation and Characterization of the Human Cytochrome P450 CYP1B1 Gene

1996 • 225 citations

Expression of CYP1B1 in human adult and fetal tissues and differential inducibility of CYP1B1 and CYP1A1 by Ah receptor ligands in human placenta and cultured cells

1997 • 206 citations

Expression of xenobiotic-metabolizing cytochrome P450 forms in human adult and fetal liver

1994 • 204 citations

A monoclonal antibody to a subset of human monocytes found only in the peripheral blood and inflammatory tissues.

1986 • 203 citations

Drug disposition and drug hypersensitivity

1987 • 199 citations

The calcium‐binding proteins MRP8 and MRP14 form a membrane‐associated heterodimer in a subset of monocytes/macrophages present in acute but absent in chronic inflammatory lesions

1992 • 192 citations

A slow acetylator genotype is a risk factor for sulphonamide-induced toxic epidermal necrolysis and Stevens-Johnson syndrome

1995 • 143 citations

T Cell Recognition of Haptens, a Molecular View

1994 • 122 citations

Genetic Polymorphism of Cytochromes P450 1A1, 2D6 and 2E1: Regulation and Toxicological Significance

1995 • 112 citations

Cell-specific regulation of human CYP1A1 and CYP1B1 genes.

1997 • 110 citations

Relevance of induction of human drug‐metabolizing enzymes: pharmacological and toxicological implications

1996 • 103 citations

Phenotyping of cytochromes P -450 in human tissues with monoclonal antibodies

1982 • 94 citations

Multiple Cytochrome P450 Isozymes in Murine Skin: Induction of P450 1A, 2B, 2E, and 3A by Dexamethasone

1994 • 80 citations

The versatility of macrophages

1992 • 77 citations

A rapid and efficient purification of poly(A)-mRNA by oligo(dT)30-Latex.

1988 • 68 citations

Ah receptor regulation of CYP1B1 expression in primary mouse embryo-derived cells.

1997 • 65 citations

Purification and immunological characterization of a novel cytochrome P450 from C3H/10T1/2 cells

1991 • 64 citations

Low N‐acetylating capacity in patients with Stevens‐Johnson syndrome and toxic epidermal necrolysis*

1995 • 61 citations

Characterization of a novel anti-inflammatory factor produced by RM3/1 macrophages derived from glucocorticoid treated human monocytes

1995 • 41 citations

Immunohistochemistry of drug-metabolizing enzymes

1995 • 36 citations

Immunologic mechanisms of cutaneous drug reactions

1996 • 35 citations

Acetylator Phenotype in Patients with <i>p</i><i>-</i>Phenylenediamine Allergy

1997 • 25 citations

Comparative assessment of metabolic enzyme levels in macrophage populations of the F344 rat

1995 • 24 citations