Peroxisome Proliferator-Activated Receptor δ Suppresses 11β-Hydroxysteroid Dehydrogenase Type 2 Gene Expression in Human Placental Trophoblast Cells

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*

1999 • 2,880 citations

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ

1997 • 2,100 citations

Purification, Characterization, andin vitroDifferentiation of Cytotrophoblasts from Human Term Placentae*

1986 • 1,556 citations

Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

2003 • 1,260 citations

Peroxisome Proliferator-activated Receptors α and γ Are Activated by Indomethacin and Other Non-steroidal Anti-inflammatory Drugs

1997 • 1,106 citations

Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

1999 • 1,065 citations

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation.

1995 • 926 citations

Minireview: Lipid Metabolism, Metabolic Diseases, and Peroxisome Proliferator-Activated Receptors

2003 • 864 citations

Growth, Adipose, Brain, and Skin Alterations Resulting from Targeted Disruption of the Mouse Peroxisome Proliferator-Activated Receptor β(δ)

2000 • 641 citations

Effects of peroxisome proliferator-activated receptor δ on placentation, adiposity, and colorectal cancer

2001 • 591 citations

Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta

1999 • 589 citations

Transcriptional Repression of Atherogenic Inflammation: Modulation by PPARδ

2003 • 580 citations

Identification, Characterization, and Tissue Distribution of Human Peroxisome Proliferator-activated Receptor (PPAR) Isoforms PPARγ2 versus PPARγ1 and Activation with Retinoid X Receptor Agonists and Antagonists

1997 • 422 citations

Prostacyclin-mediated activation of peroxisome proliferator-activated receptor δ in colorectal cancer

2000 • 396 citations

Glucocorticoid programming of the fetus; adult phenotypes and molecular mechanisms

2001 • 391 citations

Peroxisome Proliferator-Activated Receptor γ-Dependent Repression of the Inducible Nitric Oxide Synthase Gene

2000 • 377 citations

The peroxisome proliferator-activated receptor δ, an integrator of transcriptional repression and nuclear receptor signaling

2002 • 305 citations

Type 2 11 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: its relationship to birth weight and putative role in fetal adrenal steroidogenesis.

1995 • 278 citations

Reduced Placental 11β-Hydroxysteroid Dehydrogenase Type 2 mRNA Levels in Human Pregnancies Complicated by Intrauterine Growth Restriction: An Analysis of Possible Mechanisms

2001 • 270 citations

11Beta-hydroxysteroid dehydrogenase type 2 in human pregnancy and reduced expression in intrauterine growth restriction

1998 • 264 citations

cDNA cloning of a mouse prostacyclin receptor. Multiple signaling pathways and expression in thymic medulla

1994 • 255 citations

Immunohistochemical localization of the 11 beta-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta.

1995 • 243 citations

Retinoid X receptors are essential for early mouse development and placentogenesis

1999 • 176 citations

Peroxisome Proliferator-activated Receptor δ (PPARδ)-mediated Regulation of Preadipocyte Proliferation and Gene Expression Is Dependent on cAMP Signaling

2001 • 172 citations

Dual Function of 11β-Hydroxysteroid Dehydrogenase in Placenta: Modulating Placental Glucocorticoid Passage and Local Steroid Action1

1999 • 148 citations

Placental 11 beta-hydroxysteroid dehydrogenase: barrier to maternal glucocorticoids

1997 • 123 citations

Defects of the Chorioallantoic Placenta in Mouse RXRα Null Fetuses

1997 • 118 citations

PPARα Activators Inhibit Vascular Endothelial Growth Factor Receptor-2 Expression by Repressing Sp1-Dependent DNA Binding and Transactivation

2003 • 107 citations

Oxygen Regulation of Placental 11β-Hydroxysteroid Dehydrogenase 2: Physiological and Pathological Implications

2002 • 100 citations

Expression of PPAR and RXR Isoforms in the Developing Rat and Human Term Placentas

2002 • 100 citations

Alterations of Peroxisome Proliferator-activated Receptor δ Activity Affect Fatty Acid-controlled Adipose Differentiation

2000 • 99 citations

Inhibition of placental 11β-hydroxysteroid dehydrogenase type 2 by catecholamines via α-adrenergic signaling

2001 • 96 citations

Differential Regulation of 11 β-Hydroxysteroid Dehydrogenase Type 1 and 2 by Nitric Oxide in Cultured Human Placental Trophoblast and Chorionic Cell Preparation*

1997 • 95 citations

Regulation of 1lβ-Hydroxysteroid Dehydrogenase Activity in the Baboon Placenta by Estrogen*

1990 • 92 citations

Transcription Suppression of Thromboxane Receptor Gene by Peroxisome Proliferator-activated Receptor-γ via an Interaction with Sp1 in Vascular Smooth Muscle Cells

2002 • 90 citations

Correlation between expression of peroxisome proliferator-activated receptor β and squamous differentiation in epidermal and tracheobronchial epithelial cells

1999 • 86 citations

Glucocorticoids Stimulate the Expression of 11β-Hydroxysteroid Dehydrogenase Type 2 in Cultured Human Placental Trophoblast Cells

2004 • 84 citations

Regulation of 11β-Hydroxysteroid Dehydrogenase Type 2 by Progesterone, Estrogen, and the Cyclic Adenosine 5′-Monophosphate Pathway in Cultured Human Placental and Chorionic Trophoblasts1

1998 • 83 citations

The Expression of 11β-Hydroxysteroid Dehydrogenase Type 2 Is Induced during Trophoblast Differentiation: Effects of Hypoxia

2002 • 71 citations

Apparent mineralocorticoid excess due to 11β‐hydroxysteroid dehydrogenase deficiency: a possible cause of intrauterine growth retardation

1996 • 68 citations

The Regulation of Transplacental Cortisol- Cortisone Metabolism by Estrogen in Pregnant Baboons*

1988 • 64 citations

Retinoic Acid Stimulates the Expression of 11β-Hydroxysteroid Dehydrogenase Type 2 in Human Choriocarcinoma JEG-3 Cells1

1999 • 50 citations

Prostaglandins and Leukotriene B4 Are Potent Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 2 Activity in Human Choriocarcinoma JEG-3 Cells1

1999 • 42 citations

In Vivo Footprinting of the Human 11β-Hydroxysteroid Dehydrogenase Type 2 Promoter

2002 • 42 citations

Regulation of 11β-hydroxysteroid dehydrogenase type 2 activity and mRNA in human choriocarcinoma cells

1996 • 42 citations

Estrogen Regulates 11β-Hydroxysteroid Dehydrogenase-1 and -2 Localization in Placental Syncytiotrophoblast in the Second Half of Primate Pregnancy

2001 • 40 citations

Glucocorticoid actions and metabolism in pregnancy: Implications for placental function and fetal cardiovascular activity

1998 • 39 citations

Analysis of the promoter of the NAD+ dependent 11β-hydroxysteroid dehydrogenase (HSD11K) gene in JEG-3 human choriocarcinoma cells

1996 • 37 citations

Cloning of the 11β-hydroxysteroid dehydrogenase (11β-HSD)-2 gene in the baboon: effects of estradiol on promoter activity of 11β-HSD-1 and -2 in placental JEG-3 cells

1999 • 25 citations

Calcium Inhibits Human Placental 11β-Hydroxysteroid Dehydrogenase Type 2 Activity

2001 • 18 citations

Deleted Work

1955 • 0 citations