11Beta-hydroxysteroid dehydrogenase type 2 in human pregnancy and reduced expression in intrauterine growth restriction

Fetal and infant growth and impaired glucose tolerance at age 64.

1991 • 2,734 citations

Fetal and placental size and risk of hypertension in adult life.

1990 • 1,737 citations

Inadequate maternal vascular response to placentation in pregnancies complicated by pre‐eclampsia and by small‐for‐gestational age infants

1986 • 1,618 citations

Glucocorticoid exposure in utero: new model for adult hypertension

1993 • 873 citations

Cloning and tissue distribution of the human 1 lβ-hydroxysteroid dehydrogenase type 2 enzyme

1994 • 707 citations

Prenatal Exposure to Prednisone in Humans and Animals Retards Intrauterine Growth

1978 • 540 citations

11β-Hydroxysteroid Dehydrogenase and the Syndrome of Apparent Mineralocorticoid Excess*

1997 • 515 citations

Placental 11β‐hydroxysteroid dehydrogenase: a key regulator of fetal glucocorticoid exposure

1997 • 515 citations

Actions of Placental and Fetal Adrenal Steroid Hormones in Primate Pregnancy*

1995 • 469 citations

The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization.

1991 • 434 citations

Syndrome of apparent mineralocorticoid excess. A defect in the cortisol-cortisone shuttle.

1988 • 420 citations

Inhibition of 11β-Hydroxysteroid Dehydrogenase in Pregnant Rats and the Programming of Blood Pressure in the Offspring

1996 • 311 citations

Elevated levels of umbilical cord plasma corticotropin-releasing hormone in growth-retarded fetuses.

1993 • 297 citations

The ontogeny of 11 beta-hydroxysteroid dehydrogenase type 2 and mineralocorticoid receptor gene expression reveal intricate control of glucocorticoid action in development.

1996 • 281 citations

Type 2 11 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: its relationship to birth weight and putative role in fetal adrenal steroidogenesis.

1995 • 278 citations

Human placental 11 beta-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoform.

1993 • 263 citations

Immunohistochemical localization of the 11 beta-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta.

1995 • 243 citations

Conversion of maternal cortisol to cortisone during placental transfer to the human fetus

1974 • 236 citations

Hypertension in the syndrome of apparent mineralocorticoid excess due to mutation of the 11β-hydroxysteroid dehydrogenase type 2 gene

1996 • 235 citations

Reduced placental villous tree elaboration in small-for-gestational-age pregnancies: Relationship with umbilical artery Doppler waveforms

1995 • 226 citations

The Localization and Distribution of Corticotropin-Releasing Hormone in the Human Placenta and Fetal Membranes throughout Gestation*

1991 • 181 citations

Human kidney 11 beta-hydroxysteroid dehydrogenase is a high affinity nicotinamide adenine dinucleotide-dependent enzyme and differs from the cloned type I isoform.

1994 • 176 citations

Differential Expression of 11β-Hydroxysteroid Dehydrogenase Types 1 and 2 in Human Placenta and Fetal Membranes¹

1997 • 164 citations

Dexamethasone and estradiol treatment in pregnant rhesus macaques: Effects on gestational length, maternal plasma hormones, and fetal growth

1983 • 135 citations

The Placental Bed

1996 • 123 citations

Type 2 11 beta-hydroxysteroid dehydrogenase in human fetal tissues.

1994 • 116 citations

Detection of human 11β-hydroxysteroid dehydrogenase isoforms using reverse-transcriptase-polymerase chain reaction and localization of the type 2 isoform to renal collecting ducts

1995 • 106 citations

Human 11β-hydroxysteroid dehydrogenase: Studies on the stably transfected isoforms and localization of the type 2 isozyme within renal tissue

1997 • 100 citations

11β-hydroxysteroid dehydrogenase activity (E.C. 1.1.1.146) in human placenta and decidua

1980 • 97 citations

Regulation of 1lβ-Hydroxysteroid Dehydrogenase Activity in the Baboon Placenta by Estrogen*

1990 • 92 citations

11β‐Hydroxysteroid dehydrogenase: implications for clinical medicine

1996 • 83 citations

Immunodetection of 11β-Hydroxysteroid Dehydrogenase Type 2 in Human Mineralocorticoid Target Tissues: Evidence for Nuclear Localization*

1997 • 79 citations

Variation in placental type 2 11β-hydroxysteroid dehydrogenase activity is not related to birth weight or placental weight

1997 • 69 citations

Apparent mineralocorticoid excess due to 11β‐hydroxysteroid dehydrogenase deficiency: a possible cause of intrauterine growth retardation

1996 • 68 citations

RATIO CORTISONE/CORTISOL IN MOTHER AND INFANT AT BIRTH

1962 • 52 citations

Developmental increase in expression of the messenger ribonucleic acid and protein levels of 11beta-hydroxysteroid dehydrogenase types 1 and 2 in the baboon placenta.

1996 • 52 citations

Ontogeny and sexual dimorphic expression of mouse type 2 11β-hydroxysteroid dehydrogenase

1997 • 50 citations

11β-Hydroxysteroid Dehydrogenase Activity of the Human Placenta during Pregnancy

1986 • 35 citations

The Lack of Influence of Labor on Human Placental lljS-Hydroxysteroid Dehydrogenase Activity

1982 • 20 citations

Deleted Work

1955 • 0 citations