Negative Regulation of MEKK1-induced Signaling by Glutathione S-Transferase Mu

The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I

1995 • 3,492 citations

Regulation of JNK signaling by GSTp

1999 • 1,102 citations

Differential Activation of ERK and JNK Mitogen-Activated Protein Kinases by Raf-1 and MEKK

1994 • 1,092 citations

A Divergence in the MAP Kinase Regulatory Network Defined by MEK Kinase and Raf

1993 • 1,086 citations

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

1994 • 706 citations

Glutathione S-Transferase Mu Modulates the Stress-activated Signals by Suppressing Apoptosis Signal-regulating Kinase 1

2001 • 397 citations

Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

1998 • 395 citations

The three-dimensional structure of class pi glutathione S-transferase in complex with glutathione sulfonate at 2.3 A resolution.

1991 • 356 citations

Signal Transduction Pathways Regulated by Mitogen-activated/Extracellular Response Kinase Kinase Kinase Induce Cell Death

1996 • 346 citations

Ras-dependent growth factor regulation of MEK kinase in PC12 cells

1994 • 322 citations

Role of MEKK1 in Cell Survival and Activation of JNK and ERK Pathways Defined by Targeted Gene Disruption

1998 • 322 citations

Role of Glutathione S-Transferases in Protection against Lipid Peroxidation

2001 • 305 citations

MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

1997 • 300 citations

MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration

2000 • 279 citations

The ups and downs of MEK kinase interactions

2001 • 277 citations

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

1997 • 257 citations

A non-enzymatic p21 protein inhibitor of stress-activated protein kinases

1996 • 248 citations

MEK Kinase 1, a Substrate for DEVD-Directed Caspases, Is Involved in Genotoxin-Induced Apoptosis

1998 • 236 citations

Activation of multiple proline-directed kinases by bacterial lipopolysaccharide in murine macrophages.

1996 • 215 citations

JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension

1998 • 201 citations

Direct Interaction between Ras and the Kinase Domain of Mitogen-activated Protein Kinase Kinase Kinase (MEKK1)

1995 • 177 citations

MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase.

1995 • 157 citations

14-3-3 Proteins Interact with Specific MEK Kinases

1998 • 146 citations

Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain.

1996 • 134 citations

Activation of c-Jun N-terminal Kinase Antagonizes an Anti-apoptotic Action of Bcl-2

1997 • 132 citations

The TAO of MEKK

1998 • 132 citations

Effects of mGST A4 Transfection on 4-Hydroxynonenal-Mediated Apoptosis and Differentiation of K562 Human Erythroleukemia Cells

1999 • 124 citations

MEKK1 Binds Directly to the c-Jun N-terminal Kinases/Stress-activated Protein Kinases

1997 • 111 citations

MEKK1 interacts with ?-actinin and localizes to stress fibers and focal adhesions

1999 • 93 citations

Activation of p21-CDC42/Rac-Activated Kinases by CD28 Signaling: p21-Activated Kinase (PAK) and MEK Kinase 1 (MEKK1) May Mediate the Interplay Between CD3 and CD28 Signals

1998 • 80 citations

Differential Involvement of MEK Kinase 1 (MEKK1) in the Induction of Apoptosis in Response to Microtubule-targeted Drugsversus DNA Damaging Agents

1999 • 71 citations

Isolation, Characterization, and Expression in Escherichia coli of Two Murine Mu Class Glutathione S-Transferase cDNAs Homologous to the Rat Subunits 3 (Yb1) and 4 (Yb2)

1989 • 59 citations

Role of Receptor-interacting Protein in Tumor Necrosis Factor-α-dependent MEKK1 Activation

2001 • 32 citations

MEKK1 Is Essential for DT40 Cell Apoptosis in Response to Microtubule Disruption

2001 • 27 citations

A Molecular Genetic Approach for the Identification of Essential Residues in Human Glutathione S-Transferase Function in Escherichia coli

1995 • 26 citations

hUBC9 associates with MEKK1 and type I TNF‐α receptor and stimulates NFκB activity

1998 • 22 citations

Cited By (0)

Loading...