The protective role of adenosine in inducing nitric oxide synthesis in rat liver ischemia preconditioning is mediated by activation of adenosine A₂receptors

Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes.

1986 • 821 citations

Ischemic preconditioning slows energy metabolism and delays ultrastructural damage during a sustained ischemic episode.

1990 • 777 citations

Essential role of adenosine, adenosine A1 receptors, and ATP-sensitive K+ channels in cerebral ischemic preconditioning.

1995 • 558 citations

Protective effect of preconditioning on the injury associated to hepatic ischemia-reperfusion in the rat: Role of nitric oxide and adenosine

1997 • 338 citations

Endothelial Release of Nitric Oxide Contributes to the Vasodilator Effect of Adenosine in Humans

1995 • 234 citations

Protection of the heart by ischaemic preconditioning: mechanisms and possibilities for pharmacological exploitation

1994 • 226 citations

Increased adenosine concentration in blood from ischemic myocardium by AICA riboside. Effects on flow, granulocytes, and injury.

1989 • 203 citations

Intestinal Preconditioning Is Mediated by a Transient Increase in Nitric Oxide

1996 • 190 citations

Induction of manganese superoxide dismutase in rat cardiac myocytes increases tolerance to hypoxia 24 hours after preconditioning.

1994 • 173 citations

Liver Ischemic Preconditioning Is Mediated by the Inhibitory Action of Nitric Oxide on Endothelin

1996 • 171 citations

Extracellular action of adenosine and the antagonism by aminophylline on the atrioventricular conduction of isolated perfused guinea pig and rat hearts.

1982 • 147 citations

Selective adenosine A3 receptor stimulation reduces ischemic myocardial injury in the rabbit heart

1997 • 133 citations

Preconditioning: effect upon lesion modulation in warm liver ischemia.

1993 • 132 citations

Nucleoside transport inhibition: a therapeutic approach to cardioprotection via adenosine?

1993 • 127 citations

Phorbol esters induce nitric oxide synthase activity in rat hepatocytes. Antagonism with the induction elicited by lipopolysaccharide.

1992 • 118 citations

Effect of adenosine receptor modulation on pentylenetetrazole‐induced seizures in rats

1997 • 112 citations

Propentofylline: A nucleoside transport inhibitor with neuroprotective effects in cerebral ischemia

1994 • 78 citations

Ischaemic preconditioning is protein kinase C dependent but not through stimulation of adrenergic or adenosine receptors in the isolated rat heart

1995 • 63 citations

Dual activation of adenosine A1 and A3 receptors mediates preconditioning of isolated cardiac myocytes

1997 • 62 citations

Cardiac Preconditioning

1993 • 44 citations

The pathophysiology of ischaemic preconditioning

1995 • 37 citations

NITRIC OXIDE DONORS IMPROVE GUT FUNCTION AFTER PROLONGED HYPOTHERMIC ISCHEMIA

1995 • 36 citations

Nitric Oxide Participates in the Hypotensive Effect Induced by Adenosine A2 Subtype Receptor Stimulation

1995 • 25 citations

Adenosine's Effect on Myocardial Functional Recovery: Substrate or Signal?

1994 • 20 citations

Pathophysiological Characteristics of Cutaneous Microcirculation in Patients with Liver Cirrhosis: Relationships to Cardiovascular Hemodynamics and Plasma Neurohormonal Factors

1993 • 20 citations

Effects of an inhibitor of adenosine deaminase, deoxycoformycin, and of nucleoside transport, propentofylline, on post-ischemic recovery of adenine nucleotides in rat brain

1996 • 10 citations