Nucleoside transport inhibition: a therapeutic approach to cardioprotection via adenosine?

The cardiac effects of adenosine

1989 • 779 citations

How does adenosine inhibit transmitter release?

1988 • 649 citations

Turnover of adenosine in plasma of human and dog blood

1989 • 524 citations

Adenosine: a physiological modulator of superoxide anion generation by human neutrophils.

1983 • 467 citations

Adenosine and the concept of ‘retaliatory metabolites’

1984 • 422 citations

The control of the metabolism and the hormonal role of adenosine.

1978 • 416 citations

Reduction of reperfusion injury in the canine preparation by intracoronary adenosine: importance of the endothelium and the no-reflow phenomenon.

1987 • 378 citations

Cardiac electrophysiology of adenosine. Basic and clinical concepts.

1991 • 374 citations

Nucleoside and nucleobase transport in animal cells

1988 • 367 citations

Aspirin and dipyridamole in the prevention of acute coronary thrombosis complicating coronary angioplasty.

1987 • 334 citations

Dipyridamole cardiac imaging

1988 • 207 citations

Reduction of myocardial reperfusion injury by intravenous adenosine administered during the early reperfusion period.

1991 • 183 citations

Adenine nucleotide release from isolated perfused guinea pig hearts and extracellular formation of adenosine.

1991 • 164 citations

Ionic basis for the antagonism between adenosine and isoproterenol on isolated mammalian ventricular myocytes.

1984 • 150 citations

Physiological and pharmacological properties of adenosine: Therapeutic implications

1991 • 145 citations

Formation and release of purine catabolites during hypoperfusion, anoxia, and ischemia

1987 • 143 citations

Adenosine: The prototypic neuromodulator

1989 • 127 citations

Blood-tissue exchange via transport and transformation by capillary endothelial cells.

1989 • 125 citations

Endogenous adenosine inhibits platelet aggregation during myocardial ischemia in dogs.

1991 • 114 citations

Protection against epinephrine-induced myocardial necrosis by drugs that inhibit platelet aggregation

1972 • 95 citations

Augmenting intracellular adenosine improves myocardial recovery

1990 • 86 citations

Cardiac Sympathetic Activity in Myocardial Ischemia: Release and Effects of Noradrenaline

1991 • 81 citations

Absolute rates of adenosine formation during ischaemia in rat and pigeon hearts

1988 • 70 citations

Uptake and deamination of adenosine by blood species differences, effect of pH, ions, temperature and metabolic inhibitors

1969 • 70 citations

Release of nucleosides and nucleotides from the rabbit heart by sympathetic nerve stimulation

1982 • 68 citations

Adenosine regulates the respiratory burst of cytokine-triggered human neutrophils adherent to biologic surfaces.

1989 • 62 citations

Beneficial effect of adenosine during reperfusion following prolonged cardioplegic arrest

1990 • 54 citations

Comparative Pharmacology of Nucleoside Transport Inhibitors

1991 • 49 citations

Adenosine-induced hyperemia attenuates myocardial ischemia in coronary microembolization in dogs

1989 • 49 citations

Oxygen partial pressure and free intracellular adenosine of isolated cardiomyocytes

1991 • 48 citations

Intracoronary adenosine administration during reperfusion following 3 hours of ischemia: Effects on infarct size, ventricular function, and regional myocardial blood flow

1990 • 45 citations

Coronary flow increases induced by adenosine and adenine nucleotides are mediated by the coronary endothelium: a new principle of the regulation of coronary flow

1989 • 40 citations

Adenosine metabolism in microvessels from heart and brain

1986 • 39 citations

Myocardial ischemia during intravenous prostacyclin administration: Hemodynamic findings and precautionary measures

1987 • 35 citations

Cardioprotective effects of nucleoside transport inhibition in rabbit hearts

1991 • 34 citations

Biochemical and functional effects of nucleoside transport inhibition in the isolated cat heart

1989 • 34 citations

Prevention of Catecholamine-Induced Cardiac Damage and Death with a Nucleoside Transport Inhibitor

1992 • 31 citations

Formation and release of nucleosides in the ischemic myocardium. Is the guinea-pig the exception?

1985 • 30 citations

A new concept of long-term donor heart preservation: nucleoside transport inhibition.

1991 • 30 citations

Polymorphonuclear leukocyte activity and ventricular arrhythmia in acute myocardial infarction

1988 • 28 citations

Salvage of ischemic myocardium by dipyridamole in the conscious dog.

1981 • 26 citations

The adenosine hypothesis of metabolic regulation of coronary flow in the light of newly recognized properties of the coronary endothelium.

1989 • 24 citations

Effects of nucleoside transport inhibition on long-term ex vivo preservation of canine hearts

1992 • 23 citations

The role of leukocytes in ischemic damage, reperfusion injury and repair of the myocardium

1990 • 22 citations

Oral pretreatment with mioflazine completely changes the pattern and remarkably prolongs the accumulation of nucleosides in ischemic and reperfused myocardium

1986 • 17 citations

Augmentation of Coronary Flow Improves Myocardial Function in Exercise

1990 • 16 citations

Comparison of the Existing Nucleoside Transport Inhibitors: in vitro and in vivo Data

1991 • 12 citations

Role of nucleoside transport inhibition and endogenous adenosine in prevention of catecholamine induced death in rabbits

1993 • 12 citations

LIDOFLAZINE IN THE EARLY STAGES OF ACUTE MYOCARDIAL ISCHAEMIA

1982 • 12 citations

Inhibition of nucleoside uptake in human erythrocytes by a new series of compounds related to lidoflazine and mioflazine

1990 • 10 citations

Nucleoside transport inhibition and fMLP-stimulated whole blood luminescence

1991 • 9 citations

Nucleotide Metabolism and Cellular Damage in Myocardial Ischemia

1985 • 9 citations

Effect of nucleoside transport inhibition on adenosine and hypoxanthine accumulation in the ischemic human myocardium.

1993 • 8 citations

Dipyridamole for coronary artery bypass surgery

1990 • 8 citations

Effects of dilazep in evolving myocardial infarction in dogs: a biochemical study

1989 • 6 citations

Differential inactivation of adenosine by human and canine blood

1969 • 6 citations

Intravenous administration of adenosine attenuates myocardial stunning in the rabbit heart

1991 • 1 citations

Biochemical basis for reperfusion arrhythmias

1986 • 1 citations