Kinetics of anaphylatoxin C5a receptor expression during experimental allergic encephalomyelitis

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.

1993 • 837 citations

Chemotactic response to human C3a and C5a anaphylatoxins. I. Evaluation of C3a and C5a leukotaxis in vitro and under stimulated in vivo conditions.

1978 • 567 citations

C5a-induced expression of P-selectin in endothelial cells.

1994 • 470 citations

Myelin: Biology and Chemistry

1992 • 436 citations

C5A Anaphylatoxin and Its Seven Transmembrane-Segment Receptor

1994 • 418 citations

Chemotactic Response to Human C3a and C5a Anaphylatoxins

1978 • 393 citations

Comparative Neuropathology of Chronic Experimental Allergic Encephalomyelitis and Multiple Sclerosis

1983 • 295 citations

Type 1 astrocytes and oligodendrocyte‐type 2 astrocyte glial progenitors migrate toward distinct molecules

1990 • 286 citations

The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement

1991 • 284 citations

Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis.

1997 • 284 citations

Chemotactic and Anaphylatoxic Fragment Cleaved from the Fifth Component of Guinea Pig Complement

1968 • 283 citations

Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system.

1997 • 237 citations

Characterization of microglia and macrophages in the central nervous system of rats: Definition of the differential expression of molecules using standard and novel monoclonal antibodies in normal CNS and in four models of parenchymal reaction

1993 • 224 citations

Chemotaxis by a CNS macrophage, the microglia

1990 • 215 citations

Structure, function and cellular expression of complement anaphylatoxin receptors

1995 • 207 citations

Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia

1995 • 207 citations

A Macrophage Invasion Mechanism of Pathogenic Mycobacteria

1997 • 204 citations

Phagocytic activity of macrophages and microglial cells during the course of acute and chronic relapsing experimental autoimmune encephalomyelitis

1994 • 202 citations

Soluble recombinant complement receptor 1 inhibits inflammation and demyelination in antibody-mediated demyelinating experimental allergic encephalomyelitis.

1994 • 201 citations

Microglial and astroglial reactions to inflammatory lesions of experimental autoimmune encephalomyelitis in the rat central nervous system

1992 • 174 citations

Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytes.

1995 • 163 citations

Complement activation by isolated myelin: activation of the classical pathway in the absence of myelin-specific antibodies.

1982 • 160 citations

THE ROLE OF COMPLEMENT IN THE PATHOGENESIS OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

1989 • 156 citations

The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement

1991 • 136 citations

Vascular cell adhesion molecule-1 modulation by tumor necrosis factor in experimental allergic encephalomyelitis

1994 • 131 citations

Macrophage/microglial-mediated primary demyelination and motor disease induced by the central nervous system production of interleukin-3 in transgenic mice.

1996 • 111 citations

1,25 Dihydroxyvitamin D3 Exerts Regional Effects in the Central Nervous System during Experimental Allergic Encephalomyelitis

1996 • 98 citations

Enhanced expression of chemotactic receptors in multiple sclerosis lesions

1996 • 88 citations

CNS antigen presentation

1995 • 82 citations

TNF-alpha-mediated expression of the receptor for anaphylatoxin C5a on neurons in experimental Listeria meningoencephalitis.

1997 • 79 citations

Chronic relapsing experimental allergic encephalomyelitis in the Lewis rat

1985 • 78 citations

Regulation and function of central nervous system chemokines

1995 • 75 citations

Complement (C5)-derived chemotactic activity accounts for accumulation of polymorphonuclear leukocytes in cerebrospinal fluid of rabbits with pneumococcal meningitis

1984 • 73 citations

Experimental diffuse axonal injury induces enhanced neuronal C5a receptor mRNA expression in rats

1997 • 72 citations

Studies on demyelination in vitro: the requirement of membrane attack components of the complement system.

1983 • 68 citations

The role of complement in inflammation during experimental pneumococcal meningitis

1986 • 60 citations

Myelin-induced experimental allergic encephalomyelitis in Lewis rats: tumor necrosis factor α levels in serum and cerebrospinal fluid Immunohistochemical expression in glial cells and macrophages of optic nerve and spinal cord

1996 • 46 citations

Inhibition of Complement-Factor-5a-Induced Inflammatory Reactions by Prostaglandin E2 in Experimental Meningitis

1989 • 35 citations

Characterization of rat C5a anaphylatoxin receptor (C5aR): cloning of rat C5aR cDNA and study of C5aR expression by rat astrocytes

1997 • 28 citations

cDNA Cloning and Characterization of Rat C5a Anaphylatoxin Receptor

1997 • 26 citations

Morphological study in the early stages of complement C5a fragment-induced experimental meningitis: activation of macrophages and astrocytes

1995 • 26 citations

Elevated complement C5a receptor expression on neurons and glia in astrocyte-targeted interleukin-3 transgenic mice

1998 • 20 citations

Strategies for Inhibition of Complement Activation in the Treatment of Neurodegenerative Diseases

1998 • 18 citations

The Complement System in Demyelination

2023 • 6 citations

ELEVATED COMPLEMENT C5A RECEPTOR EXPRESSION ON GLIAL CELLS AND NEURONS INDUCED BY THE CENTRAL NERVOUS SYSTEM PRODUCTION OF INTERLEUKIN-3 IN TRANSGENIC MICE

1998 • 2 citations