Neurons Undergo Apoptosis in Animal and Cell Culture Models of Diabetes

The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus

1993 • 23,535 citations

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Mitochondria and Apoptosis

1998 • 8,909 citations

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

1997 • 4,728 citations

Disruption of epithelial cell-matrix interactions induces apoptosis

1994 • 3,167 citations

Oxidative damage and mitochondrial decay in aging.

1994 • 2,024 citations

Diabetes Mellitus and Its Degenerative Complications: A Prospective Study of 4,400 Patients Observed Between 1947 and 1973

1978 • 1,311 citations

Integrins and anoikis

1997 • 1,145 citations

Mitochondria and apoptosis

1998 • 892 citations

A Dissection and tissue culture manual of the nervous system

1989 • 762 citations

The Central Executioner of Apoptosis: Multiple Connections between Protease Activation and Mitochondria in Fas/APO-1/CD95- and Ceramide-induced Apoptosis

1997 • 625 citations

The Effect of Intensive Diabetes Therapy on the Development and Progression of Neuropathy

1995 • 577 citations

In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system

1998 • 366 citations

TUNEL Apoptotic Cell Detection in Tissue Sections: Critical Evaluation and Improvement

1998 • 358 citations

High-Glucose–Triggered Apoptosis in Cultured Endothelial Cells

1995 • 342 citations

Nonradioactive labeling of oligonucleotides in vitro with the hapten digoxigenin by tailing with terminal transferase

1991 • 322 citations

Endogenous levels of nerve growth factor (NGF) are altered in experimental diabetes mellitus: A possible role for NGF in the pathogenesis of diabetic neuropathy

1990 • 316 citations

The Rochester Diabetic Neuropathy Study

1991 • 299 citations

Nerve growth factor administration protects against experimental diabetic sensory neuropathy

1994 • 287 citations

Pathologic Alterations in the Diabetic Neuropathies of Humans

1996 • 286 citations

Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats

1994 • 244 citations

Apoptosis Is the Mode of β-Cell Death Responsible for the Development of IDDM in the Nonobese Diabetic (NOD) Mouse

1997 • 203 citations

Oxidative stress measurement by in vivo electron spin resonance spectroscopy in rats with streptozotocin-induced diabetes

1998 • 196 citations

Insulin-like Growth Factors Regulate Neuronal Differentiation and Survival

1997 • 189 citations

BETA-CELL APOPTOSIS IS RESPONSIBLE FOR THE DEVELOPMENT OF IDDM IN THE MULTIPLE LOW-DOSE STREPTOZOTOCIN MODEL

1996 • 181 citations

Role of Neurotrophins in Diabetic Neuropathy and Treatment with Nerve Growth Factors

1997 • 181 citations

Insulin-like growth factor I rescues SH-SY5Y human neuroblastoma cells from hyperosmotic induced programmed cell death

1996 • 169 citations

Type I Insulin-like Growth Factor Receptor Activation Regulates Apoptotic Proteins

1996 • 162 citations

Neuronal Apoptosis in Creutzfeldt-Jakob Disease

1999 • 161 citations

Neurites Can Remain Viable after Destruction of the Neuronal Soma by Programmed Cell Death (Apoptosis)

1994 • 154 citations

Pathogenesis of Diabetic Neuropathy

1998 • 139 citations

PATHOLOGICAL OBSERVATIONS ON SIX CASES OF DIABETIC NEUROPATHY

1964 • 131 citations

Insulin-like growth factor I receptor prevents apoptosis and enhances neuroblastoma tumorigenesis.

1996 • 128 citations

Insulin-like growth factor-I prevents apoptosis in neurons after nerve growth factor withdrawal

1998 • 121 citations

Bidirectional Regulation of p38 Kinase and c-Jun N-terminal Protein Kinase by Insulin-like Growth Factor-I

1998 • 114 citations

Insulin-Like Growth Factor-I Prevents Apoptosis in Sympathetic Neurons Exposed to High Glucose

1999 • 101 citations

Neuropathology and blood flow of nerve, spinal roots and dorsal root ganglia in longstanding diabetic rats

1997 • 101 citations

Alloxan diabetic neuropathy

1977 • 96 citations

Neurotrophins and peripheral neuropathy

1996 • 81 citations

The effect of nerve growth factor, ciliary neurotrophic factor, and ACTH analogs on cisplatin neurotoxicity in vitro

1994 • 80 citations

The effect of insulin treatment on myelinated nerve fibre maturation and integrity and on body growth in streptozotocin-diabetic rats

1985 • 70 citations

Sural nerve myelinated fiber density differences associated with meaningful changes in clinical and electrophysiologic measurements

1996 • 61 citations

Insulin-like growth factor-I is an osmoprotectant in human neuroblastoma cells

1997 • 60 citations

Reduced Perikaryal Volume of Lower Motor and Primary Sensory Neurons in Early Experimental Diabetes

1980 • 59 citations

Acute hyperosmolar hyperglycemia causes axonal shrinkage and reduced nerve conduction velocity

1981 • 53 citations

Effect of cisplatin and ACTH4–9 on neural transport in cisplatin induced neurotoxicity

1995 • 51 citations

Alzheimer's disease: Clues from flies and worms

1999 • 50 citations

The determination of an empirical correction factor to deal with the problem of nucleolar splitting in neuronal counts

1984 • 47 citations

Apoptotic Cell Death in Neurons and Glial Cells: Implications for Alzheimer’s Disease

1999 • 47 citations

Severe radicular pathology in rats with longstanding diabetes

1994 • 44 citations

Fate of Schwann Cells in CMT1A and HNPP: Evidence for Apoptosis

1998 • 36 citations

FLOW CYTOMETRIC SCORING OF APOPTOSIS COMPARED TO ELECTRON MICROSCOPY IN γ IRRADIATED LYMPHOCYTES

1998 • 32 citations

Role of nerve growth factor in suramin neurotoxicity studied in vitro

1994 • 31 citations

Low bcl-2 expression and increased spontaneous apoptosis in T-lymphocytes from newly-diagnosed IDDM patients

1995 • 21 citations

Influence of age on the late retrograde effects of sciatic nerve section in the rat.

1995 • 19 citations

Extracellular adhesive molecules in neurite growth

1989 • 18 citations

The metabolism of glucose of nerve cells cultivated under different conditions

1976 • 16 citations

IGFs in the Nervous System

1998 • 11 citations

IGF-I in Neuronal Differentiation and Neuroprotection

1998 • 3 citations