Formation of the tetraploid intermediate is associated with the development of cells with more than four centrioles in the elastase-simian virus 40 tumor antigen transgenic mouse model of pancreatic cancer.

The Clonal Evolution of Tumor Cell Populations

1976 • 6,310 citations

Checkpoints: Controls That Ensure the Order of Cell Cycle Events

1989 • 3,036 citations

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1988 • 1,490 citations

Hereditary cancer, oncogenes, and antioncogenes.

1985 • 1,261 citations

The RAD9 Gene Controls the Cell Cycle Response to DNA Damage in Saccharomyces cerevisiae

1988 • 1,174 citations

The Chromosomal Basis of Human Neoplasia

1983 • 1,121 citations

p53: oncogene or anti-oncogene?

1990 • 812 citations

THE MOLECULAR GENETICS OF CELLULAR ONCOGENES

1984 • 765 citations

Gene amplification in cultured animal cells

1984 • 639 citations

Polo, a mitotic mutant of Drosophila displaying abnormal spindle poles

1988 • 546 citations

Duplication of Spindle Plaques and Integration of the Yeast Cell Cycle

1974 • 419 citations

Ultrastructural Pathology of the Cell and Matrix

1982 • 412 citations

Clinical and biological significance of aneuploidy in human tumours.

1984 • 410 citations

ALTERED FIDELITY OF MITOTIC CHROMOSOME TRANSMISSION IN CELL CYCLE MUTANTS OF S. CEREVISIAE

1985 • 390 citations

Barrett's esophagus

1987 • 282 citations

Model for the genetic evolution of human solid tumors.

1989 • 251 citations

Pancreatic Neoplasia Induced by SV40 T-Antigen Expression in Acinar Cells of Transgenic Mice

1987 • 243 citations

Progression to cancer in Barrett's esophagus is associated with genomic instability.

1989 • 225 citations

Nuclear and cytoplasmic mitotic cycles continue in Drosophila embryos in which DNA synthesis is inhibited with aphidicolin.

1988 • 222 citations

Centrosome duplication continues in cycloheximide-treated Xenopus blastulae in the absence of a detectable cell cycle.

1990 • 176 citations

Ploidy and proliferation in human bladder tumors as measured by flow-cytofluorometric DNA-analysis and its relations to histopathology and cytology

1979 • 167 citations

Mitosis in a cell with multiple centrioles.

1982 • 158 citations

p53 interacts with p34cdc2 in mammalian cells: implications for cell cycle control and oncogenesis.

1990 • 156 citations

Mitosis : molecules and mechanisms

1989 • 153 citations

The fission yeast cut1+ gene regulates spindle pole body duplication and has homology to the budding yeast ESP1 gene

1990 • 151 citations

A yeast gene essential for regulation of spindle pole duplication.

1988 • 137 citations

Somatic cell hybridization

1975 • 121 citations

Centriole distribution during tripolar mitosis in Chinese hamster ovary cells.

1984 • 112 citations

The simian virus 40 large T antigen. A lot packed into a little.

1987 • 76 citations

Mechanisms of chromosome distribution and aneuploidy

1991 • 73 citations

Errors in DNA synthesis: A source of spontaneous mutations

1990 • 63 citations

Microtubule-organizing centers abnormal in number, structure, and nucleating activity in x-irradiated mammalian cells.

1983 • 57 citations

DNA content and genetic evolution of human colorectal adenocarcinoma. A study by flow cytometry and cytogenetic analysis

1988 • 52 citations

A Yeast Gene Essential for Regulation of Spindle Pole Duplication

1988 • 47 citations

A comparison between flow cytometric ploidy investigation and chromosome analysis of 32 human colorectal tumors

1986 • 44 citations

Simian virus 40 large T antigen and p53 are microtubule-associated proteins in transformed cells.

1991 • 44 citations

Correlation of DNA content, p53, T antigen, and V antigen in simian virus 40‐infected human diploid cells

1989 • 31 citations

Continued DNA synthesis after a mitotic block in the double mutant cut1 cdc11 of the fission yeast Schizosaccharomyces Pombe

1990 • 23 citations

Premalignant conditions of the gastrointestinal tract

1991 • 18 citations

SV40 T‐Antigen as a Dual Oncogene: Structure and Function of the Plasma Membrane‐Associated Population^a

1989 • 17 citations

Solubilization of SV40 Plasma‐Membrane‐Associated Large Tumor Antigen Using Single‐Phase Concentrations of 1‐Butanol

1989 • 7 citations

Premalignant Conditions of the Gastrointestinal Tract

1991 • 6 citations