Errors in DNA synthesis: A source of spontaneous mutations

Dietary Carcinogens and Anticarcinogens

1983 • 3,028 citations

The aging process.

1981 • 1,871 citations

Rate of depurination of native deoxyribonucleic acid

1972 • 1,488 citations

MUTAGENESIS BY APURINIC/APYRIMIDINIC SITES

1986 • 884 citations

A new Salmonella tester strain (TA102) with A X T base pairs at the site of mutation detects oxidative mutagens.

1982 • 747 citations

Genetic studies of the lac repressor

1977 • 500 citations

Mutational specificity of depurination.

1984 • 361 citations

Methyl-directed repair of DNA base-pair mismatches in vitro.

1983 • 344 citations

High mutation frequency in DNA transfected into mammalian cells.

1983 • 338 citations

Insertion of nucleotides opposite apurinic apyrimidinic sites in deoxyribonucleic acid during in vitro synthesis: uniqueness of adenine nucleotides

1983 • 320 citations

The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations.

1985 • 317 citations

Mechanisms of spontaneous mutagenesis: An analysis of the spectrum of spontaneous mutation in the Escherichia coli lacI gene

1986 • 305 citations

Spectra of spontaneous mutations in Escherichia coli strains defective in mismatch correction: the nature of in vivo DNA replication errors.

1987 • 291 citations

Apurinic sites as mutagenic intermediates

1985 • 283 citations

Inflammation: Basic Principles and Clinical Correlates

1988 • 275 citations

A new mammalian DNA polymerase with 3' to 5' exonuclease activity: DNA polymerase δ

1976 • 258 citations

Preparation and preliminary characterization of monoclonal antibodies against human DNA polymerase alpha.

1982 • 257 citations

Different base/base mispairs are corrected with different efficiencies and specificities in monkey kidney cells

1988 • 230 citations

Rearrangement and mutagenesis of a shuttle vector plasmid after passage in mammalian cells.

1983 • 207 citations

Spontaneous Mutation: Genetic Control of Mutation Rates in Bacteriophage T4

1969 • 206 citations

Depurination causes mutations in SOS-induced cells.

1981 • 186 citations

Fidelity of Mammalian DNA Polymerases

1981 • 180 citations

Evidence for reactive oxygen species inducing mutations in mammalian cells.

1986 • 175 citations

Sequence specificity of point mutations induced during passage of a UV-irradiated shuttle vector plasmid in monkey cells.

1986 • 167 citations

DNA polymerase α

1989 • 161 citations

Mutagenesis during in vitro DNA synthesis.

1978 • 147 citations

Depurination-induced infidelity of DNA synthesis with purified DNA replication proteins in vitro

1983 • 137 citations

DNA replication and mutagenesis

1988 • 131 citations

Differential extension of 3′ mispairs is a major contribution to the high fidelity of calf thymus DNA polymerase-α

1989 • 129 citations

Exonucleolytic proofreading by calf thymus DNA polymerase delta.

1987 • 111 citations

Exonuclease III recognizes urea residues in oxidized DNA.

1985 • 99 citations

Recent studies of the fidelity of DNA synthesis

1988 • 98 citations

Spectrum of spontaneous mutation at the APRT locus of Chinese hamster ovary cells: an analysis at the DNA sequence level.

1988 • 95 citations

Spontaneous mutagenesis: the roles of DNA repair, replication, and recombination

1985 • 79 citations

Effects of depurination on the fidelity of DNA synthesis

1979 • 76 citations

Mammalian mutator mutant with an aphidicolin-resistant DNA polymerase alpha.

1983 • 74 citations

DNA sequence analysis of spontaneous mutations at the aprt locus of hamster cells.

1987 • 71 citations

Do DNA polymerases δ and α act coordinately as leading and lagging strand replicases?

1988 • 45 citations

On the fidelity of DNA replication. Isolation of high fidelity DNA polymerase-primase complexes by immunoaffinity chromatography.

1987 • 42 citations