The role of T3 in the activation of human T cells

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Inositol phospholipids and cell surface receptor function

1975 • 2,458 citations

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

1982 • 2,255 citations

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures

1980 • 2,218 citations

Monoclonal Antibodies Defining Distinctive Human T Cell Surface Antigens

1979 • 1,480 citations

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

Phorbol diester receptor copurifies with protein kinase C.

1983 • 1,185 citations

T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes

1982 • 1,026 citations

Calmodulin—an intracellular calcium receptor

1980 • 964 citations

Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

1983 • 890 citations

Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

1983 • 833 citations

OKT3: A monoclonal anti-human T lymphocyte antibody with potent mitogenic properties

1980 • 718 citations

Thyrotropin-Releasing Hormone

1982 • 680 citations

Interleukin l and T Cell Activation

1982 • 622 citations

Diacylglycerol and phorbol ester stimulate secretion without raising cytoplasmic free calcium in human platelets

1983 • 589 citations

OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties.

1980 • 525 citations

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

1982 • 494 citations

Involvement of guanine nucleotide-binding protein in the gating of Ca2+ by receptors

1983 • 473 citations

Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor

1983 • 464 citations

Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line.

1980 • 436 citations

Polymorphism in mitogenic effect of IgG1 monoclonal antibodies against T3 antigen on human T cells

1983 • 333 citations

Phospholipid degradation and signal translation for protein phosphorylation

1983 • 323 citations

Does OKT3 monoclonal antibody react with an antigen-recognition structure on human T cells?

1981 • 306 citations

Monoclonal antibodies against the antigen receptor on a cloned T-cell hybrid.

1983 • 293 citations

The role of calcium ions in initiating transformation of lymphocytes

1974 • 271 citations

Insulin secretion: Combined effects of phorbol ester and A23187

1983 • 250 citations

A monoclonal antibody blocking human T cell function

1980 • 239 citations

Surface Structures Involved in Target Recognition by Human Cytotoxic T Lymphocytes

1982 • 238 citations

The Genetic Control of HLA‐A and B Antigens in Somatic Cell Hybrids: Requirement for β₂ Microglobulin

1978 • 222 citations

Macrophage-independent activation of helper T cells. I. Production of Interleukin 2.

1980 • 219 citations

The mouse T cell receptor: Comparison of MHC-restricted receptors on two T cell hybridomas

1983 • 218 citations

The mouse T cell receptor: Structural heterogeneity of molecules of normal T cells defined by Xenoantiserum

1983 • 217 citations

Calcium and cell function

1983 • 207 citations

The T3 complex on human T lymphocytes involves four structurally distinct glycoproteins.

1983 • 194 citations

Aldosterone secretion: Effect of phorbol ester and A23187

1983 • 175 citations

Complexity of the human T lymphocyte-specific cell surface antigen T3.

1982 • 170 citations

The Human T Cell Receptor: Analysis with Cytotoxic T Cell Clones

1983 • 163 citations

Studies on the mechanism by which phytohemagglutinin rapidly stimulates phospholipid metabolism of human lymphocytes

1971 • 144 citations

Signal requirements for T lymphocyte activation. I. Replacement of macrophage function with phorbol myristic acetate.

1979 • 134 citations

Comparison of T3-associated 49- and 43-kilodalton cell surface molecules on individual human T-cell clones: evidence for peptide variability in T-cell receptor structures.

1983 • 133 citations

Cellular origin and interactions involved in gamma-interferon production induced by OKt3 monoclonal antibody.

1982 • 129 citations

A possible role of protein kinase C in signal-induced lysosomal enzyme release

1983 • 128 citations

Thyrotropin releasing hormone

1982 • 124 citations

Biosynthesis and molecular nature of the T3 antigen of human T lymphocytes.

1983 • 110 citations

Intracellular free calcium concentrations in isolated pancreatic acini; Effects of secretagogues

1983 • 107 citations

The T3 complex on human thymus‐derived lymphocytes contains two different subunits of 20 kDa

1983 • 99 citations

Ca 2+ and protein kinase C: Two synergistic cellular signals

1983 • 86 citations

Human gamma interferon production by leukocytes induced with monoclonal antibodies recognizing T cells.

1981 • 85 citations

Evidence for Cyclic GMP and Calcium Mediation of Lymphocyte Activation by Mitogens

1977 • 83 citations

A new possible regulatory system for protein phosphorylation in human peripheral lymphocytes. I. Characterization of a calcium-activated, phospholipid-dependent protein kinase.

1981 • 82 citations

Signal Requirements for T Lymphocyte Activation

1979 • 63 citations

A new possible regulatory system for protein phosphorylation in human peripheral lymphocytes. II. Possible relation to phosphatidylinositol turnover induced by mitogens.

1981 • 59 citations

Calcium and Phospholipid Turnover as Transmembrane Signaling for Protein Phosphorylation

1982 • 40 citations

Production and regulation of interleukin-2 in human lymphoblastic leukemias studied with T-cell monoclonal antibodies

1983 • 33 citations

Biosynthesis, glycosylation, and in vitro translation of the human T cell antigen Leu-4.

1983 • 27 citations

The Replacement of Monocytes and Interleukin-1 by Phorbol Ester in Lectin-Induced Proliferation of Human Thymocytes and T Cells

1982 • 23 citations