DNA-binding motifs from eukaryotic transcription factors

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

TRANSCRIPTION FACTORS: Structural Families and Principles of DNA Recognition

1992 • 1,411 citations

Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5

1993 • 1,269 citations

Crystal structure of a yeast TBP/TATA-box complex

1993 • 1,082 citations

Co-crystal structure of TBP recognizing the minor groove of a TATA element

1993 • 1,039 citations

The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted α Helices: Crystal structure of the protein-DNA complex

1992 • 964 citations

The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: How receptors discriminate between their response elements

1993 • 745 citations

Crystal structure of globular domain of histone H5 and its implications for nucleosome binding

1993 • 739 citations

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

1993 • 723 citations

Crystal Structure of a Five-Finger GLI-DNA Complex: New Perspectives on Zinc Fingers

1993 • 679 citations

The helix-turn-helix DNA binding motif

1989 • 616 citations

Eukaryotic RNA Polymerase

1985 • 500 citations

The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly

1991 • 497 citations

NMR Structure of a Specific DNA Complex of Zn-Containing DNA Binding Domain of GATA-1

1993 • 456 citations

Crystal structure of TFIID TATA-box binding protein

1992 • 410 citations

Structure of the HMG box motif in the B-domain of HMG1.

1993 • 403 citations

Structure and function of the b/HLH/Z domain of USF.

1994 • 390 citations

Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains.

1992 • 298 citations

Structure of the Retinoid X Receptor α DNA Binding Domain: a Helix Required for Homodimeric DNA Binding

1993 • 296 citations

The X-ray Structure of the GCN4-bZIP Bound to ATF/CREB Site DNA Shows the Complex Depends on DNA Flexibility

1993 • 285 citations

Solution structure of a DNA-binding domain from HMG1

1993 • 275 citations

Solution structure of a DNA-binding unit of Myb: a helix-turn-helix-related motif with conserved tryptophans forming a hydrophobic core.

1992 • 241 citations

Interactions of coiled coils in transcription factors: where is the specificity?

1993 • 190 citations

Nucleosome displacement in transcription

1993 • 179 citations

Kinetic analysis of yeast TFIID-TATA box complex formation suggests a multi-step pathway.

1992 • 178 citations

Three in one and one in three: It all depends on TBP

1993 • 174 citations

Interaction of TFIID in the minor groove of the TATA element

1991 • 170 citations

Yeast and human TFIID with altered DNA-binding specificity for TATA elements

1992 • 155 citations

Crystal structure of yeast TATA-binding protein and model for interaction with DNA.

1993 • 150 citations

Advances in RNA polymerase II transcription

1992 • 149 citations

Advances in RNA polymerase II transcription

1992 • 144 citations

Solution structure of the POU-specific DNA-binding domain of Oct-1

1993 • 144 citations

The SRY high-mobility-group box recognizes DNA by partial intercalation in the minor groove: a topological mechanism of sequence specificity.

1993 • 137 citations

The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage λ repressor DNA-binding domain

1993 • 133 citations

A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex.

1993 • 128 citations

Structure of a new nucleic-acid-binding motif in eukaryotic transcriptional elongation factor TFIIS

1993 • 116 citations

2.1 Å resolution refined structure of a TATA box-binding protein (TBP)

1994 • 102 citations

Refined solution structure of the glucocorticoid receptor DNA-binding domain

1993 • 98 citations

Regional Codon Randomization: Defining a TATA-Binding Protein Surface Required for RNA Polymerase III Transcription

1993 • 95 citations

NMR detection of hydration water in the intermolecular interface of a protein-DNA complex

1993 • 83 citations

Adaptability at the protein-DNA interface is an important aspect of sequence recognition by bZIP proteins.

1993 • 76 citations

Identification of an amino acid–base contact in the GCN4–DNA complex by bromouracil-mediated photocrosslinking

1992 • 76 citations

High affinity DNA-binding Myc analogs: Recognition by an α helix

1993 • 75 citations

The X-ray structure of an atypical homeodomain present in the rat liver transcription factor LFB1/HNF1 and implications for DNA binding.

1993 • 68 citations

The X-ray structure of an atypical homeodomain present in the rat liver transcription factor LFB1/HNF1 and implications for DNA binding.

1993 • 55 citations

Thermodynamics of the glucocorticoid receptor-DNA interaction: Binding of wild-type GR DBD to different response elements

1993 • 53 citations

The solution structure of the human retinoic acid receptor-β DNA-binding domain

1993 • 53 citations

Backbone dynamics of the glucocorticoid receptor DNA-binding domain

1992 • 48 citations

Folding topology of the disulfide-bonded dimeric DNA-binding domain of the myogenic determination factor MyoD

1992 • 36 citations

The three-dimensional NMR-solution structure of the polypeptide fragment 195-286 of the LFB1/HNF1 transcription factor from rat liver comprises a nonclassical homeodomain.

1993 • 34 citations

Secondary structure of the oct‐3 POU homeodomain as determined by ¹H‐¹⁵N NMR spectroscopy

1993 • 17 citations