Back to search

An essential amino acid induces epithelial β-defensin expression

Data up to Jan 2025

Published2000
Citations113
References44

Total Citations Per Year

Abstract

References (44)

Phylogenetic Perspectives in Innate Immunity

1999 • 2,478 citations

Innate Immunity: The Virtues of a Nonclonal System of Recognition

1997 • 2,397 citations

The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

1994 • 2,124 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

β-Defensins: Linking Innate and Adaptive Immunity Through Dendritic and T Cell CCR6

1999 • 1,760 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

1995 • 1,601 citations

The immune system evolved to discriminate infectious nonself from noninfectious self

1992 • 1,324 citations

Determination ofD-amino acids. II. Use of a bifunctional reagent, 1,5-difluoro-2,4-dinitrobenzene

1984 • 1,307 citations

The inducible transcription activator NF-κB: regulation by distinct protein subunits

1991 • 1,079 citations

Regulation of Intestinal α-Defensin Activation by the Metalloproteinase Matrilysin in Innate Host Defense

1999 • 1,069 citations

Human β-Defensin-1 Is a Salt-Sensitive Antibiotic in Lung That Is Inactivated in Cystic Fibrosis

1997 • 1,069 citations

Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.

1999 • 602 citations

Transcriptional regulation of the IL-2 gene

1995 • 579 citations

Production of β-defensins by human airway epithelia

1998 • 574 citations

Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants

1998 • 573 citations

Widespread expression of beta‐defensin hBD‐1 in human secretory glands and epithelial cells

1996 • 571 citations

Expression and Regulation of the Human β-Defensins hBD-1 and hBD-2 in Intestinal Epithelium

1999 • 496 citations

A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing

1988 • 485 citations

Epithelial Antibiotics Induced at Sites of Inflammation

1995 • 417 citations

Human γδ T Cells Recognize Alkylamines Derived from Microbes, Edible Plants, and Tea

1999 • 368 citations

Production of β-Defensin Antimicrobial Peptides by the Oral Mucosa and Salivary Glands

1999 • 366 citations

Identification of 3‐hydroxypalmitic acid methyl ester as a novel autoregulator controlling virulence in Ralstonia solanacearum

1997 • 295 citations

Inducible expression of an antibiotic peptide gene in lipopolysaccharide-challenged tracheal epithelial cells.

1996 • 277 citations

Antimicrobial Peptides as Mediators of Epithelial Host Defense

1999 • 277 citations

Structure and mapping of the human β-defensin HBD-2 gene and its expression at sites of inflammation

1998 • 257 citations

Defensins

1995 • 256 citations

The serum mannose-binding protein and the macrophage mannose receptor are pattern recognition molecules that link innate and adaptive immunity

1998 • 246 citations

Epithelial antibiotic induced in states of disease

1997 • 223 citations

NF-kappa B as inducible transcriptional activator of the granulocyte-macrophage colony-stimulating factor gene.

1990 • 205 citations

The human haptoglobin gene promoter: interleukin-6-responsive elements interact with a DNA-binding protein induced by interleukin-6.

1989 • 196 citations

Enteric β-Defensin: Molecular Cloning and Characterization of a Gene with Inducible Intestinal Epithelial Cell Expression Associated with Cryptosporidium parvum Infection

1998 • 179 citations

Isolation and characterization of beta-glucan receptors on human mononuclear phagocytes.

1991 • 161 citations

Coordinate induction of two antibiotic genes in tracheal epithelial cells exposed to the inflammatory mediators lipopolysaccharide and tumor necrosis factor alpha

1996 • 160 citations

Requirement for nuclear factor (NF)-kappa B p65 and NF-interleukin-6 binding elements in the tumor necrosis factor response region of the granulocyte colony-stimulating factor promoter

1994 • 157 citations

Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide gene.

1993 • 155 citations

LIPOPOLYSACCHARIDE RECOGNITION, CD14, AND LIPOPOLYSACCHARIDE RECEPTORS

1999 • 147 citations

Cellular Responses to Fmlp Challenging: A Mini-Review

1999 • 135 citations

Inhibition of NF-κB activation in vitro and in vivo: Role of 26S proteasome

1999 • 89 citations

Branched‐chain fatty acids: the case for a novel form of cell‐cell signalling during Myxococcus xanthus development

1995 • 82 citations

NF-κΒ as Inducible Transcriptional Activator of the Granulocyte-Macrophage Colony-Stimulating Factor Gene

1990 • 59 citations

Bacterial DNA as an evolutionary conserved ligand signalling danger of infection to immune cells

1998 • 48 citations

Endothelial and Epithelial Cells Do Not Respond to Complexes of Peptidoglycan with Soluble CD14 but Are Activated Indirectly by Peptidoglycan‐Induced Tumor Necrosis Factor‐α and Interleukin‐1 from Monocytes

1998 • 36 citations

Scratching the Surface

1999 • 14 citations

Cited By (0)

Loading...
An essential amino acid induces epithelial β-defensin expression (2000) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer