An essential amino acid induces epithelial β-defensin expression
Data up to Jan 2025
Total Citations Per Year
Abstract
References (44)
Phylogenetic Perspectives in Innate Immunity
1999 • 2,478 citations
Innate Immunity: The Virtues of a Nonclonal System of Recognition
1997 • 2,397 citations
The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB
1994 • 2,124 citations
Improved retroviral vectors for gene transfer and expression.
1989 • 1,997 citations
β-Defensins: Linking Innate and Adaptive Immunity Through Dendritic and T Cell CCR6
1999 • 1,760 citations
NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control
1989 • 1,622 citations
Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin
1995 • 1,601 citations
The immune system evolved to discriminate infectious nonself from noninfectious self
1992 • 1,324 citations
Determination ofD-amino acids. II. Use of a bifunctional reagent, 1,5-difluoro-2,4-dinitrobenzene
1984 • 1,307 citations
The inducible transcription activator NF-κB: regulation by distinct protein subunits
1991 • 1,079 citations
Regulation of Intestinal α-Defensin Activation by the Metalloproteinase Matrilysin in Innate Host Defense
1999 • 1,069 citations
Human β-Defensin-1 Is a Salt-Sensitive Antibiotic in Lung That Is Inactivated in Cystic Fibrosis
1997 • 1,069 citations
Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.
1999 • 602 citations
Transcriptional regulation of the IL-2 gene
1995 • 579 citations
Production of β-defensins by human airway epithelia
1998 • 574 citations
Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants
1998 • 573 citations
Widespread expression of beta‐defensin hBD‐1 in human secretory glands and epithelial cells
1996 • 571 citations
Expression and Regulation of the Human β-Defensins hBD-1 and hBD-2 in Intestinal Epithelium
1999 • 496 citations
A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing
1988 • 485 citations
Epithelial Antibiotics Induced at Sites of Inflammation
1995 • 417 citations
Human γδ T Cells Recognize Alkylamines Derived from Microbes, Edible Plants, and Tea
1999 • 368 citations
Production of β-Defensin Antimicrobial Peptides by the Oral Mucosa and Salivary Glands
1999 • 366 citations
Identification of 3‐hydroxypalmitic acid methyl ester as a novel autoregulator controlling virulence in Ralstonia solanacearum
1997 • 295 citations
Inducible expression of an antibiotic peptide gene in lipopolysaccharide-challenged tracheal epithelial cells.
1996 • 277 citations
Antimicrobial Peptides as Mediators of Epithelial Host Defense
1999 • 277 citations
Structure and mapping of the human β-defensin HBD-2 gene and its expression at sites of inflammation
1998 • 257 citations
Defensins
1995 • 256 citations
The serum mannose-binding protein and the macrophage mannose receptor are pattern recognition molecules that link innate and adaptive immunity
1998 • 246 citations
Epithelial antibiotic induced in states of disease
1997 • 223 citations
NF-kappa B as inducible transcriptional activator of the granulocyte-macrophage colony-stimulating factor gene.
1990 • 205 citations
The human haptoglobin gene promoter: interleukin-6-responsive elements interact with a DNA-binding protein induced by interleukin-6.
1989 • 196 citations
Enteric β-Defensin: Molecular Cloning and Characterization of a Gene with Inducible Intestinal Epithelial Cell Expression Associated with Cryptosporidium parvum Infection
1998 • 179 citations
Isolation and characterization of beta-glucan receptors on human mononuclear phagocytes.
1991 • 161 citations
Coordinate induction of two antibiotic genes in tracheal epithelial cells exposed to the inflammatory mediators lipopolysaccharide and tumor necrosis factor alpha
1996 • 160 citations
Requirement for nuclear factor (NF)-kappa B p65 and NF-interleukin-6 binding elements in the tumor necrosis factor response region of the granulocyte colony-stimulating factor promoter
1994 • 157 citations
Airway epithelial cells are the site of expression of a mammalian antimicrobial peptide gene.
1993 • 155 citations
LIPOPOLYSACCHARIDE RECOGNITION, CD14, AND LIPOPOLYSACCHARIDE RECEPTORS
1999 • 147 citations
Cellular Responses to Fmlp Challenging: A Mini-Review
1999 • 135 citations
Inhibition of NF-κB activation in vitro and in vivo: Role of 26S proteasome
1999 • 89 citations
Branched‐chain fatty acids: the case for a novel form of cell‐cell signalling during Myxococcus xanthus development
1995 • 82 citations
NF-κΒ as Inducible Transcriptional Activator of the Granulocyte-Macrophage Colony-Stimulating Factor Gene
1990 • 59 citations
Bacterial DNA as an evolutionary conserved ligand signalling danger of infection to immune cells
1998 • 48 citations
Endothelial and Epithelial Cells Do Not Respond to Complexes of Peptidoglycan with Soluble CD14 but Are Activated Indirectly by Peptidoglycan‐Induced Tumor Necrosis Factor‐α and Interleukin‐1 from Monocytes
1998 • 36 citations
Scratching the Surface
1999 • 14 citations