Transient Acquired Thermotolerance in Drosophila, Correlated with Rapid Degradation of Hsp70 During Recovery

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis

1986 • 2,566 citations

Cyclin is degraded by the ubiquitin pathway

1991 • 2,355 citations

THE FUNCTION OF HEAT-SHOCK PROTEINS IN STRESS TOLERANCE: DEGRADATION AND REACTIVATION OF DAMAGED PROTEINS

1993 • 2,177 citations

Protein disaggregation mediated by heat-shock protein Hspl04

1994 • 861 citations

HSP104 Required for Induced Thermotolerance

1990 • 822 citations

Correlation between synthesis of heat shock proteins and development of thermotolerance in Chinese hamster fibroblasts.

1982 • 754 citations

Stress proteins in biology and medicine

1990 • 731 citations

Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells.

1989 • 699 citations

The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptor.

1993 • 652 citations

Heat Shock Is Lethal to Fibroblasts Microinjected with Antibodies Against hsp70

1988 • 635 citations

The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels

1982 • 542 citations

Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins.

1990 • 520 citations

Stress proteins in biology and medicine

1990 • 502 citations

Synthesis and degradation of heat shock proteins during development and decay of thermotolerance.

1982 • 433 citations

Heat-shock protein hsp90 governs the activity of pp60v-src kinase.

1993 • 420 citations

hsp70: Nuclear concentration during environmental stress and cytoplasmic storage during recovery

1984 • 400 citations

Characterization of the thermotolerant cell. I. Effects on protein synthesis activity and the regulation of heat-shock protein 70 expression.

1988 • 399 citations

The consequences of expressing hsp70 in Drosophila cells at normal temperatures.

1992 • 398 citations

Ubiquitin is a heat shock protein in chicken embryo fibroblasts.

1985 • 392 citations

Thermal response of rat fibroblasts stably transfected with the human 70-kDa heat shock protein-encoding gene.

1991 • 365 citations

Dynamic changes in the structure and intracellular locale of the mammalian low-molecular-weight heat shock protein.

1988 • 356 citations

Induction of thermotolerance and enhanced heat shock protein synthesis in chinese hamster fibroblasts by sodium arsenite and by ethanol

1983 • 306 citations

The preferential translation of Drosophila hsp70 mRNA requires sequences in the untranslated leader

1985 • 291 citations

Heat shock proteins and thermotolerance; a comparison of induction kinetics

1982 • 264 citations

Effect of heat shock on protein degradation in mammalian cells: involvement of the ubiquitin system.

1987 • 235 citations

The Effect of Heat Shock on Gene Expression in Drosophila melanogaster

1978 • 226 citations

Eukaryotic homologues of Escherichia coli dnaJ: a diverse protein family that functions with hsp70 stress proteins.

1993 • 225 citations

Heat shock proteins in thermotolerance and other cellular processes.

1987 • 220 citations

Characterization of the thermotolerant cell. II. Effects on the intracellular distribution of heat-shock protein 70, intermediate filaments, and small nuclear ribonucleoprotein complexes.

1988 • 195 citations

[28] Quantitative two-dimensional gel electrophoresis of proteins

1983 • 188 citations

Sequence homologies in the 5' regions of four Drosophila heat-shock genes.

1981 • 188 citations

c-myc and c-myb protein degradation: effect of metabolic inhibitors and heat shock.

1988 • 154 citations

Heat-resistant variants of Chinese hamster fibroblasts altered in expression of heat shock protein.

1985 • 151 citations

Chapter 27 Two-Dimensional Polyacrylamide Gel Electrophoretic Fractionation

1977 • 149 citations

Microinjection of ubiquitin: changes in protein degradation in HeLa cells subjected to heat-shock.

1987 • 145 citations

Changes in hsp70 alter thermotolerance and heat-shock regulation in Drosophila.

1991 • 141 citations

Small heat shock proteins in may confer thermal tolerance

1983 • 130 citations

Analysis of the resistance to heat and hydrogen peroxide stresses in COS cells transiently expressing wild type or deletion mutants of the Drosophila 27‐kDa heat‐shock protein

1993 • 129 citations

Enhanced constitutive expression of the 27‐kDa heat shock proteins in heat‐resistant variants from chinese hamster cells

1988 • 128 citations

Expression and Localization of Drosophila melanogaster hsp70 Cognate Proteins

1986 • 125 citations

Heat-shock proteins Hsp104 and Hsp70 reactivate mRNA splicing after heat inactivation

1995 • 120 citations

The ClpP component of Clp protease is the sigma 32-dependent heat shock protein F21.5

1990 • 117 citations

Evaluation of isoelectric focusing running conditions during two-dimensional isoelectric focusing/sodium dodecyl sulfate-polyacrylamide gel electrophoresis: Variation of gel patterns with changing conditions and optimized isoelectric focusing conditions

1984 • 114 citations

Effects of cycloheximide on thermotolerance expression, heat shock protein synthesis, and heat shock protein mRNA accumulation in rat fibroblasts.

1986 • 102 citations

Thermotolerance in Mammalian Cells: A Possible Role for Heat Shock Proteins

1985 • 100 citations

The relationship of heat-shock proteins, thermotolerance, and protein synthesis

1988 • 92 citations

Expression and localization of Drosophila melanogaster hsp70 cognate proteins.

1986 • 92 citations

Mutations affecting the stability of the fushi tarazu protein of Drosophila.

1990 • 85 citations

Interactions of the heme-regulated eIF-2 alpha kinase with heat shock proteins in rabbit reticulocyte lysates.

1992 • 71 citations

Self-degradation of heat shock proteins.

1985 • 68 citations

Heat Shock Protein Levels Are Not Elevated in Heat-Resistant B16 Melanoma Cells

1986 • 43 citations

Induction of translational thermotolerance in liver of thermally stressed rats

1993 • 43 citations

Protection of Chinese Hamster Ovary Cells from Heat Killing by Treatment with Cycloheximide or Puromycin: Involvement of HSPs?

1987 • 42 citations

Heat Shock Effects on Phosphorylation of Protein Synthesis Initiation Factor Proteins eIF-4E and eIF-2.alpha. in Drosophila

1995 • 37 citations

Thermotolerance in the absence of induced heat shock proteins in a murine lymphoma.

1992 • 25 citations

Acquisition of thermotolerance induced by heat and arsenite in HeLa S3 cells: Multiple pathways to induce tolerance?

1992 • 23 citations

Heat shock gene expression and development of translational thermotolerance in human hepatoblastoma cells.

1993 • 13 citations

Heat shock-induced repression of proteolysis: poly(A)-binding protein degradation patterns can illusorily suggest its specific loss during heat shock

1994 • 9 citations