Alcohol dehydrogenase gene of Drosophila melanogaster: relationship of intervening sequences to functional domains in the protein.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

Why genes in pieces?

1978 • 2,256 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

The structure and evolution of the human β-globin gene family

1980 • 1,398 citations

Are snRNPs involved in splicing?

1980 • 1,206 citations

Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries.

1978 • 1,117 citations

The evolution of genes: the chicken preproinsulin gene

1980 • 725 citations

Isolation and partial characterization of the Drosophila alcohol dehydrogenase gene.

1980 • 570 citations

Split Genes and RNA Splicing

1979 • 467 citations

Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain.

1978 • 419 citations

Codon frequencies in 119 individual genes confirm corsistent choices of degenerate bases according to genome type

1980 • 370 citations

Implications of RNA⋅RNA Splicing in Evolution of Eukaryotic Cells

1978 • 333 citations

Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments

1979 • 329 citations

Sequence of three copies of the gene for the major Drosophila heat shock induced protein and their flanking regions

1980 • 286 citations

Ovomucoid intervening sequences specify functional domains and generate protein polymorphism

1980 • 152 citations

Nucleotide sequence homology at 12 intron–exon junctions in the chick ovalbumin gene

1978 • 145 citations

Immunoglobulin heavy chain gene organization in mice: analysis of a myeloma genomic clone containing variable and alpha constant regions.

1979 • 131 citations

Differences between Alcohol Dehydeogenases

1977 • 110 citations

A computer-assisted model for estimating protein secondary structure from circular dichroic spectra: Comparison of animal lactate dehydrogenases

1980 • 109 citations

Design, synthesis and characterisation of a 34-residue polypeptide that interacts with nucleic acids

1979 • 103 citations

Characterization of globin domains: Heme binding to the central exon product

1980 • 100 citations

Exons encode protein functional units

1979 • 99 citations

Secondary-structure prediction from the sequence of Drosophila melanogaster (fruitfly) alcohol dehydrogenase

1980 • 61 citations

Structural analysis of the ADHS electromorph of Drosophila melanogaster.

1978 • 43 citations

Chemical basis of the electrophoretic variation observed at the alcohol dehydrogenase locus of Drosophila melanogaster

1979 • 20 citations

Genetic distances from mRNA sequences

1980 • 19 citations