Activation and substrate specificity of the human protein kinase C α and ζ isoenzymes

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

A Manual of Methods for Baculovirus Vectors and Insect Cell Culture Procedures.

1987 • 1,703 citations

Signaling through phosphatidylcholine breakdown.

1990 • 1,362 citations

Protein kinase C isoenzymes: divergence in signal transduction?

1993 • 1,237 citations

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

1986 • 1,150 citations

Protein Kinase C Contains a Pseudosubstrate Prototope in Its Regulatory Domain

1987 • 1,020 citations

Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

1993 • 966 citations

Protein kinase C

1991 • 914 citations

The structure, expression, and properties of additional members of the protein kinase C family.

1988 • 706 citations

Lysosphingolipids Inhibit Protein Kinase C: Implications for the Sphingolipidoses

1987 • 593 citations

Inhibition of cell proliferation by alpha-tocopherol. Role of protein kinase C.

1991 • 510 citations

Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties.

1989 • 508 citations

Overproduction of protein kinase C causesdisordered growth control in rat fibroblasts

1988 • 492 citations

Activation of protein kinase C by Triton X-100 mixed micelles containing diacylglycerol and phosphatidylserine.

1985 • 471 citations

Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequence.

1989 • 439 citations

Purification and characterization of the zeta isoform of protein kinase C from bovine kidney.

1992 • 283 citations

Effect of phorbol esters on protein kinase C-zeta.

1992 • 282 citations

Potent and Specific Inhibitors of Protein Kinase C of Microbial Origin

1990 • 262 citations

Role of Raf-1 serine/threonine protein kinase in growth factor signal transduction.

1991 • 248 citations

Protein kinase C contains two phorbol ester binding domains.

1991 • 234 citations

Expression, purification, and characterization of protein kinase C-epsilon.

1990 • 231 citations

Isolation and characterization of delta-subspecies of protein kinase C from rat brain.

1992 • 218 citations

Vitamin E inhibits protein kinase c activity

1988 • 169 citations

Evidence for a Role of Protein Kinase C ζ Subspecies in Maturation of Xenopus laevis Oocytes

1992 • 162 citations

Expression of four protein kinase C isoforms in rat fibroblasts. Distinct subcellular distribution and regulation by calcium and phorbol esters.

1992 • 160 citations

Isolation and characterization of the epsilon subspecies of protein kinase C from rat brain.

1992 • 140 citations

Translocation of protein kinase C isozymes in thrombin-stimulated human platelets. Correlation with 1,2-diacylglycerol levels.

1992 • 130 citations

Protein kinase C group B members PKC-δ, -ɛ, -ζ and PKC-L(η). Comparison of properties of recombinant proteins in vitro and in vivo

1992 • 121 citations

Distinct mechanisms of regulation of protein kinase C epsilon by hormones and phorbol diesters.

1991 • 107 citations

Expression and characterization of protein kinase C‐δ

1991 • 94 citations

Identification of multiple PKC isoforms in Swiss 3T3 cells: Differential down‐regulation by phorbol ester

1992 • 90 citations

Protein kinase Cζ and n in murine epidermis TPA induces down‐regulation of PKCn but not PKCζ

1992 • 88 citations

Role of Raf-1 serine/threonine protein kinase in growth factor signal transduction.

1991 • 86 citations

Protein kinase C autophosphorylates by an intrapeptide reaction.

1987 • 83 citations

Evidence for a role of protein kinase C zeta subspecies in maturation of Xenopus laevis oocytes.

1992 • 83 citations

Different translocation of three distinct PKC isoforms with tumor-promoting phorbol ester in human platelets

1991 • 76 citations

Expression and partial characterization of rat protein kinase C‐δ and protein kinase C‐ξ in insect cells using recombinant baculovirus

1992 • 73 citations

Failure of wild-type or a mutant form of protein kinase C-α to transform fibroblasts

1991 • 68 citations

Immunocharacterization of δ‐ and ζ‐isoenzymes of protein kinase C in rat renal mesangial cells

1992 • 67 citations

Proteolytic activation of protein kinase C‐ɛ

1990 • 65 citations

Sequence of human protein kinase C α

1990 • 64 citations

Constitutive presence of a catalytic fragment of protein kinase C epsilon in a small cell lung carcinoma cell line.

1992 • 59 citations

The regulatory domain of protein kinase C-ε restricts the catalytic-domain-specificity

1991 • 53 citations

Studies on the primary sequence requirements for PKC‐α, ‐β₁ and ‐γ peptide substrates

1990 • 49 citations

Activation of purified human protein kinase C α and β I isoenzymes in vitro by Ca2+, phosphatidylinositol and phosphatidylinositol 4,5-bisphosphate

1993 • 39 citations

Inducible overexpression of human protein kinase C α in NIH 3T3 fibroblasts results in growth abnormalities

1992 • 31 citations

Deleted Work

1955 • 0 citations