Inhibition of cell proliferation by alpha-tocopherol. Role of protein kinase C.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

The Pathogenesis of Atherosclerosis

1976 • 2,000 citations

Atherosclerosis and the Arterial Smooth Muscle Cell

1973 • 1,503 citations

Early Signals in the Mitogenic Response

1986 • 1,498 citations

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

Phorbol diester receptor copurifies with protein kinase C.

1983 • 1,185 citations

Vitamin E: application of the principles of physical organic chemistry to the exploration of its structure and function

1986 • 1,103 citations

Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins

1989 • 846 citations

Replication of smooth muscle cells in vascular disease.

1986 • 770 citations

THE PROTEIN KINASE C FAMILY: HETEROGENEITY AND ITS IMPLICATIONS

1989 • 739 citations

Disappearance of Ca2+-sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cells

1984 • 643 citations

VITAMIN E AND FREE RADICAL PEROXIDATION OF LIPIDS*

1972 • 471 citations

Phorbol esters, phospholipase C, and growth factors rapidly stimulate the phosphorylation of a Mr 80,000 protein in intact quiescent 3T3 cells.

1983 • 377 citations

Growth factor-stimulated protein phosphorylation in 3T3-L1 cells. Evidence for protein kinase C-dependent and -independent pathways.

1985 • 351 citations

Hormone-induced redistribution of calcium-activated phospholipid-dependent protein kinase in pituitary gonadotrophs.

1985 • 296 citations

Plasma Vitamins E and A Inversely Correlated to Mortality from Ischemic Heart Disease in Cross‐Cultural Epidemiology

1989 • 240 citations

Endothelin stimulates diacylglycerol accumulation and activates protein kinase C in cultured vascular smooth muscle cells

1989 • 230 citations

Vitamin E inhibits protein kinase c activity

1988 • 169 citations

Differential distribution of protein kinase C isozymes in the various regions of brain.

1987 • 150 citations

Hyperplastic growth response of vascular smooth muscle cells following induction of acute hypertension in rats by aortic coarctation.

1985 • 149 citations

Down regulation of specific binding of [20-3H]phorbol 12,13-dibutyrate and phorbol ester-induced differentiation of human promyelocytic leukemia cells.

1981 • 144 citations

Interactions of retinol with binding proteins: implications for the mechanism of uptake by cells

1990 • 127 citations

Bombesin, diacylglycerols, and phorbol esters rapidly stimulate the phosphorylation of an Mr = 80,000 protein kinase C substrate in permeabilized 3T3 cells. Effect of guanine nucleotides.

1988 • 120 citations

Vitamin E: Introduction to Biochemistry and Health Benefits

1989 • 111 citations

Modulation of Ca2+-activated, phospholipid-dependent protein kinase in platelets treated with a tumor-promoting phorbol ester

1984 • 109 citations

Possible involvement of protein kinase C in platelet-derived growth factor-stimulated DNA synthesis in vascular smooth muscle cells

1987 • 106 citations

Membrane-stabilizing effect of vitamin E: Effect of α-tocopherol and its model compounds on fluidity of lecithin liposomes

1988 • 105 citations

Increases in Intracellular Ca2+ Regulate the Binding of [3H]Phorbol 12,13-Dibutyrate to Intact 1321N1 Astrocytoma Cells

1989 • 97 citations

Differences in phorbol-ester-induced down-regulation of protein kinase C between cell lines

1989 • 93 citations

The Role of Vitamin E and Selenium on Arachidonic Acid Oxidation by way of the 5‐Lipoxygenase Pathway

1989 • 77 citations

Cytosolic calcium regulates phorbol diester binding affinity in intact phagocytes.

1986 • 76 citations

Retraction

1991 • 60 citations

Prevention of the TPA-mediated down-regulation of protein kinase C

1988 • 60 citations

Endothelin stimulates a sustained 1,2-diacylglycerol increase and protein kinase C activation in bovine aortic smooth muscle cells

1989 • 47 citations

Effects of tumor promoters on growth and on cellular redistribution of phospholipid/CA²⁺‐dependent protein kinase in human breast cancer cells

1986 • 40 citations

Platelet-derived growth factor (PDGF)-induced phospholipase C-mediated hydrolysis of phosphoinositides in vascular smooth muscle cells — different sensitivity of PDGF- and angiotensin II-induced phospholipase C reactions to protein kinase C-activating phorbol esters

1988 • 34 citations

Two types of protein kinase C with different functions in cultured rabbit aortic smooth muscle cells

1989 • 32 citations

Cancer Mortality and Vitamin E Status

1989 • 21 citations

Tocopherol‐Binding Proteins of Hepatic Cytosol

1989 • 19 citations