Alterations in behaviour and glutamate transmission following presentation of stimuli previously associated with cocaine exposure

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Drug Addiction, Dysregulation of Reward, and Allostasis

2001 • 2,820 citations

From motivation to action: Functional interface between the limbic system and the motor system

1980 • 2,292 citations

The psychology of animal learning

1975 • 1,995 citations

Conditioned Reflexes: an Investigation of the Physiological Activity of the Cerebral Cortex

1928 • 1,778 citations

An opponent-process theory of motivation: I. Temporal dynamics of affect.

1974 • 1,644 citations

Limbic Activation During Cue-Induced Cocaine Craving

1999 • 1,518 citations

Acute Effects of Cocaine on Human Brain Activity and Emotion

1997 • 1,263 citations

Conditioned place preference: what does it add to our preclinical understanding of drug reward?

2000 • 1,210 citations

Abstinence Symptomatology and Psychiatric Diagnosis in Cocaine Abusers

1986 • 1,134 citations

Frustrative nonreward in partial reinforcement and discrimination learning: Some recent history and a theoretical extension.

1962 • 966 citations

Activation of memory circuits during cue-elicited cocaine craving.

1996 • 939 citations

The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants

1998 • 936 citations

Cue-Induced Cocaine Craving: Neuroanatomical Specificity for Drug Users and Drug Stimuli

2000 • 919 citations

Substance Abuse: A Comprehensive Textbook

1998 • 721 citations

Associative Processes in Addiction and Reward The Role of Amygdala‐Ventral Striatal Subsystems

1999 • 713 citations

Conditioning factors in drug abuse: can they explain compulsion?

1998 • 680 citations

Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization

1996 • 609 citations

Dynamics of Drug Dependence

1973 • 608 citations

Neural Activity Related to Drug Craving in Cocaine Addiction

2001 • 545 citations

The Role of the Nucleus Accumbens in Instrumental Conditioning: Evidence of a Functional Dissociation between Accumbens Core and Shell

2001 • 541 citations

Conditioned responses to cocaine-related stimuli in cocaine abuse patients

1992 • 457 citations

Psychological stress, drug-related cues and cocaine craving

2000 • 451 citations

Dissociation in Conditioned Dopamine Release in the Nucleus Accumbens Core and Shell in Response to Cocaine Cues and during Cocaine-Seeking Behavior in Rats

2000 • 446 citations

Functional Magnetic Resonance Imaging of Human Brain Activation During Cue-Induced Cocaine Craving

1998 • 442 citations

Control of cocaine-seeking behavior by drug-associated stimuli in rats: Effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbens

2000 • 412 citations

Functional Magnetic Resonance Imaging of Cocaine Craving

2001 • 411 citations

Brain microdialysis of GABA and glutamate: What does it signify?

1997 • 393 citations

Regional brain metabolic activation during craving elicited by recall of previous drug experiences

1999 • 348 citations

Second-order schedules of drug reinforcement in rats and monkeys: measurement of reinforcing efficacy and drug-seeking behaviour

2000 • 309 citations

Evidence for conditional neuronal activation following exposure to a cocaine-paired environment: role of forebrain limbic structures

1992 • 291 citations

Dissociation of Pavlovian and instrumental incentive learning under dopamine antagonists.

2000 • 290 citations

Sensitization to the psychomotor stimulant effects of amphetamine: Modulation by associative learning.

1996 • 275 citations

Dissociation of Pavlovian and instrumental incentive learning under dopamine antagonists.

2000 • 244 citations

Effects of dopaminergic and glutamatergic receptor antagonists on the acquisition and expression of cocaine conditioning place preference

1995 • 239 citations

Review Article The family of sodium-dependent glutamate transporters: a focus on the GLT-1/EAAT2 subtype

1998 • 239 citations

Amphetamine-Induced Behavior, Dopamine Release, and c-fosmRNA Expression: Modulation by Environmental Novelty

1998 • 228 citations

Modulation of the Induction or Expression of Psychostimulant Sensitization by the Circumstances Surrounding Drug Administration

1998 • 228 citations

Dissociation of Primary and Secondary Reward-Relevant Limbic Nuclei in an Animal Model of Relapse

2000 • 213 citations

Sensitization to the psychomotor stimulant effects of amphetamine: Modulation by associative learning.

1996 • 211 citations

Haloperidol antagonism of cue-elicited cocaine craving

1996 • 205 citations

Cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: Studies on the involvement of dopamine

1997 • 203 citations

Experimental analysis of conditioning factors in human narcotic addiction.

1975 • 198 citations

Sensitization to the behavioral effects of cocaine: Modification by Pavlovian conditioning

1981 • 197 citations

Neural integrative activities of nucleus accumbens subregions in relation to learning and motivation

1999 • 196 citations

Evidence for sensitization of cocaine-induced nucleus accumbens glutamate release

1996 • 182 citations

Experimental approach to individual vulnerability to psychostimulant addiction

1989 • 180 citations

Acute and Repeated Systemic Amphetamine Administration: Effects on Extracellular Glutamate, Aspartate, and Serine Levels in Rat Ventral Tegmental Area and Nucleus Accumbens

1996 • 178 citations

Conditioned frustration as a learned drive.

1963 • 151 citations

Context-specific Enhancement of Glutamate Transmission by Cocaine

2000 • 149 citations

Interactions of MK-801 and GYKI 52466 with morphine and amphetamine in place preference conditioning and behavioural sensitization

1997 • 146 citations

Impact of Self-Administered Cocaine and Cocaine Cues on Extracellular Dopamine in Mesolimbic and Sensorimotor Striatum in Rhesus Monkeys

2000 • 141 citations

Conditioned effects of environmental stimuli paired with smoked cocaine in humans

2000 • 141 citations

Evidence for Opponent-Process Actions of Intravenous Cocaine

1999 • 137 citations

Pharmacology of AMPA/Kainate Receptor Ligands and Their Therapeutic Potential in Neurological and Psychiatric Disorders

2000 • 135 citations

Environmental modulation of amphetamine-induced c-fos expression in D1 versus D2 striatal neurons

1999 • 133 citations

EXPERIMENTAL COCAINE ADDICTION

1929 • 133 citations

Cocaine Abuse and Dependence

1995 • 128 citations

Expression of Fos‐related antigens in the nucleus accumbens and associated regions following exposure to a cocaine‐paired environment

2000 • 127 citations

Extinction procedures abolish conditioned stimulus control but spare sensitized responding to amphetamine

1991 • 119 citations

Classical conditioning, decay and extinction of cocaine-induced hyperactivity and stereotypy

1983 • 119 citations

Environmental Novelty Differentially Affects c-fosmRNA Expression Induced by Amphetamine or Cocaine in Subregions of the Bed Nucleus of the Stria Terminalis and Amygdala

2001 • 111 citations

Amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine

1994 • 103 citations

Contribution of NMDA receptors to postsynaptic potentials and paired-pulse facilitation in identified neurons of the rat nucleus accumbens in vitro

1991 • 99 citations

Cocaine-induced conditioned locomotion: Absence of associated increases in dopamine release

1992 • 92 citations

1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: Novel AMPA Receptor Antagonists

1997 • 88 citations

Amphetamine-Induced Plasticity of AMPA Receptors in the Ventral Tegmental Area: Effects on Extracellular Levels of Dopamine and Glutamate in Freely Moving Rats

2001 • 86 citations

Context-specific cross-sensitization between systemic cocaine and intra-accumbens AMPA infusion in the rat

1996 • 80 citations

Effects of the AMPA/kainate receptor antagonist DNQX in the nucleus accumbens on drug-induced conditioned place preference

1993 • 79 citations

Amphetamine and D1 Dopamine Receptor Agonists Produce Biphasic Effects on Glutamate Efflux in Rat Ventral Tegmental Area: Modification by Repeated Amphetamine Administration

1998 • 78 citations

Amphetamine Increases Glutamate Efflux in the Rat Ventral Tegmental Area by a Mechanism Involving Glutamate Transporters and Reactive Oxygen Species

2000 • 72 citations

Conditioned increases in anxiogenic-like behavior following exposure to contextual stimuli associated with cocaine are mediated by corticotropin-releasing factor

1998 • 71 citations

Effects of dopaminergic and glutamatergic receptor antagonists on the establishment and expression of conditioned locomotion to cocaine in rats

1996 • 70 citations

Locally evoked potentials in slices of the rat nucleus accumbens: NMDA and non-NMDA receptor mediated components and modulation by GABA

1990 • 69 citations

GYKI 52466 and related 2,3-benzodiazepines as anticonvulsant agents in DBA/2 mice

1995 • 68 citations

Amphetamine‐Induced Glutamate Efflux in the Rat Ventral Tegmental Area Is Prevented by MK‐801, SCH 23390, and Ibotenic Acid Lesions of the Prefrontal Cortex

1999 • 67 citations

DNQX in the nucleus accumbens inhibits cocaine-induced conditioned place preference

1995 • 65 citations

Locomotor response to novelty does not predict cocaine place preference conditioning in rats

1996 • 64 citations

Animals predisposed to develop amphetamine self-administration show higher susceptibility to develop contextual conditioning of both amphetamine-induced hyperlocomotion and sensitization

1994 • 64 citations

Glutamate receptor regulation of rat nucleus accumbens neurons in vivo

1996 • 63 citations

Conditioned release of corticosterone by contextual stimuli associated with cocaine is mediated by corticotropin-releasing factor

1998 • 60 citations

Morphine‐associated environmental cues elicit conditioned gene expression

2000 • 60 citations

Involvement of the Nucleus Accumbens and Medial Prefrontal Cortex in the Expression of Conditioned Hyperactivity to a Cocaine-Associated Environment in Rats

2000 • 60 citations

AMPA‐receptor involvement in c‐fos expression in the medial prefrontal cortex and amygdala dissociates neural substrates of conditioned activity and conditioned reward

1999 • 54 citations

Conditioning, habituation and behavioral reorganization factors in chronic cocaine effects

1992 • 50 citations

Disruption of Operant Oral Self‐Administration of Ethanol, Sucrose, and Saccharin by the AMP/Kainate Antagonist, NBQX, but Not the AMPA Antagonist, GYKI 52466

1999 • 49 citations

Morphine-associated environmental cues elicit conditioned gene expression

2000 • 47 citations

3,5-Dihydro-4H-2,3-benzodiazepine-4-thiones: A New Class of AMPA Receptor Antagonists

1998 • 44 citations

Reduced glutamate immunolabeling in the nucleus accumbens following extended withdrawal from self-administered cocaine

1998 • 42 citations

Effects of GYKI 52466 and CNQX, AMPA/kainate receptor antagonists, on the micturition reflex in the rat

1995 • 39 citations

Conditioned locomotor-activating and reinforcing effects of discrete stimuli paired with intraperitoneal cocaine

1997 • 36 citations

Effects of AMPA receptor antagonists on dopamine-mediated behaviors in mice

1998 • 35 citations

Effects of the competitive N-methyl-d-aspartate receptor antagonist, CPP, on the development and expression of conditioned hyperactivity and sensitization induced by cocaine

1999 • 34 citations

Conditioning as a Critical Determinant of Sensitization Induced by Psychomotor Stimulants

1990 • 31 citations

Pavlovian conditioning of psychomotor stimulant-induced behaviours

1996 • 26 citations

Classical conditioning of cocaine's stimulatory effects.

1982 • 22 citations