Amphetamine Increases Glutamate Efflux in the Rat Ventral Tegmental Area by a Mechanism Involving Glutamate Transporters and Reactive Oxygen Species

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The neural basis of drug craving: An incentive-sensitization theory of addiction

1993 • 7,074 citations

The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants

1998 • 936 citations

Nonvesicular release of neurotransmitter

1993 • 837 citations

Repeated cocaine augments excitatory amino acid transmission in the nucleus accumbens only in rats having developed behavioral sensitization

1996 • 609 citations

Invited Review Free radicals and the pathobiology of brain dopamine systems

1998 • 501 citations

Enhancement of Locomotor Activity and Conditioned Reward to Cocaine by Brain-Derived Neurotrophic Factor

1999 • 376 citations

An improved and rapid HPLC-EC method for the isocratic separation of amino acid neurotransmitters from brain tissue and microdialysis perfusates

1988 • 349 citations

Regulation of ERK ( Extracellular Signal Regulated Kinase), Part of the Neurotrophin Signal Transduction Cascade, in the Rat Mesolimbic Dopamine System by Chronic Exposure to Morphine or Cocaine

1996 • 295 citations

Inhibition by dopamine of (Na+ + K+)ATPase activity in neostriatal neurons through D1 and D2 dopamine receptor synergism

1990 • 286 citations

Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons.

1996 • 276 citations

The effects of methamphetamine on the production of free radicals and oxidative stress.

1998 • 272 citations

ACTION OF THE NEUROTOXIN KAINIC ACID ON HIGH AFFINITY UPTAKE OF <scp>l</scp>‐GLUTAMIC ACID IN RAT BRAIN SLICES

1979 • 263 citations

Effects of lesions of prefrontal cortex, amygdala, or fornix on behavioral sensitization to amphetamine: Comparison with N-methyl-d-aspartate antagonists

1995 • 263 citations

Review Article The family of sodium-dependent glutamate transporters: a focus on the GLT-1/EAAT2 subtype

1998 • 239 citations

D1 receptors modulate glutamate transmission in the ventral tegmental area

1995 • 235 citations

MK-801 prevents alterations in the mesoaccumbens dopamine system associated with behavioral sensitization to amphetamine

1994 • 203 citations

Inhibition of Ischemia-Induced Glutamate Release in Rat Striatum by Dihydrokinate and an Anion Channel Blocker

1999 • 202 citations

Neurofilament proteins and the mesolimbic dopamine system: common regulation by chronic morphine and chronic cocaine in the rat ventral tegmental area

1992 • 189 citations

Heterogeneity and Functional Properties of Subtypes of Sodium-Dependent Glutamate Transporters in the Mammalian Central Nervous System

1996 • 187 citations

Repeated Cocaine Administration Alters Extracellular Glutamate in the Ventral Tegmental Area

1998 • 186 citations

Calcium-independent release of amino acid neurotransmitters: Fact or artifact?

1992 • 179 citations

Acute and Repeated Systemic Amphetamine Administration: Effects on Extracellular Glutamate, Aspartate, and Serine Levels in Rat Ventral Tegmental Area and Nucleus Accumbens

1996 • 178 citations

Previous exposure to amphetamine increases incentive to obtain the drug: long-lasting effects revealed by the progressive ratio schedule

2000 • 171 citations

Influence of neurotrophic factors on morphine- and cocaine-induced biochemical changes in the mesolimbic dopamine system

1995 • 166 citations

Neurotrophin-3 Contributes to the Initiation of Behavioral Sensitization to Cocaine by Activating the Ras/Mitogen-Activated Protein Kinase Signal Transduction Cascade

1999 • 153 citations

Glial Fibrillary Acidic Protein and the Mesolimbic Dopamine System: Regulation by Chronic Morphine and Lewis‐Fischer Strain Differences in the Rat Ventral Tegmental Area

1993 • 143 citations

Rapid ATP Loss Caused by Methamphetamine in the Mouse Striatum: Relationship Between Energy Impairment and Dopaminergic Neurotoxicity

1994 • 140 citations

Effects of the AMPA receptor antagonist NBQX on the development and expression of behavioral sensitization to cocaine and amphetamine

1997 • 115 citations

Inhibition of Glutamate Transport in Synaptosomes by Dopamine Oxidation and Reactive Oxygen Species

1997 • 110 citations

Differential Regulation of Neurotrophin andtrkReceptor mRNAs in Catecholaminergic Nuclei during Chronic Opiate Treatment and Withdrawal

1998 • 110 citations

Two dissociable components of behavioral sensitization following repeated amphetamine administration

1982 • 87 citations

Long-Lasting Induction of Astrocytic Basic Fibroblast Growth Factor by Repeated Injections of Amphetamine: Blockade by Concurrent Treatment with a Glutamate Antagonist

1998 • 85 citations

Amphetamine increases the extracellular concentration of glutamate in striatum of the awake rat: involvement of high affinity transporter mechanisms

1999 • 82 citations

Requirement of endogenous basic fibroblast growth factor for sensitization to amphetamine.

2000 • 81 citations

Role of Oxidative Stress and the Glutathione System in Loss of Dopamine Neurons Due to Impairment of Energy Metabolism

1998 • 81 citations

Amphetamine and D1 Dopamine Receptor Agonists Produce Biphasic Effects on Glutamate Efflux in Rat Ventral Tegmental Area: Modification by Repeated Amphetamine Administration

1998 • 78 citations

Amphetamine‐Induced Glutamate Efflux in the Rat Ventral Tegmental Area Is Prevented by MK‐801, SCH 23390, and Ibotenic Acid Lesions of the Prefrontal Cortex

1999 • 67 citations

t Requirement of Endogenous Basic Fibroblast Growth Factor for Sensitization to Amphetamine

2000 • 65 citations

Expression of the GLT-1 subtype of Na+-dependent glutamate transporter: pharmacological characterization and lack of regulation by protein kinase C.

1999 • 54 citations

?-Phenyl-N-tert-butyl nitrone attenuates methamphetamine-induced depletion of striatal dopamine without altering hyperthermia

1996 • 51 citations

Regulation of Phospholipase Cγ in the Mesolimbic Dopamine System by Chronic Morphine Administration

1999 • 48 citations

A microdialysis study investigating the mechanisms of hydroxyl radical formation in rat striatum exposed to glutamate

1998 • 36 citations

Body temperature effect on methylenedioxymethamphetamine-induced acute decrease in tryptophan hydroxylase activity

1995 • 32 citations

Evidence for the involvement of phospholipase A2 mechanisms in the development of stimulant sensitization.

1996 • 25 citations

Intra-striatal infusion of d-amphetamine induces hydroxyl radical formation: inhibition by MK-801 pretreatment

2000 • 25 citations

A microdialysis study in rat brain of dihydrokainate, a glutamate uptake inhibitor

1996 • 25 citations

Body temperature effect on methylenedioxymethamphetamine-induced acute decrease in tryptophan hydroxylase activity

1995 • 7 citations

Dextro‐phenylalanine inhibits potassium‐evoked ³H‐noradrenaline release from hypothalamus but not of ³H‐dopamine from rat caudate nucleus

1980 • 4 citations