Cocaine Abuse and Dependence

The neural basis of drug craving: An incentive-sensitization theory of addiction

1993 • 7,074 citations

Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine

1987 • 2,189 citations

Cellular and Molecular Mechanisms of Drug Dependence

1988 • 2,094 citations

Abstinence Symptomatology and Psychiatric Diagnosis in Cocaine Abusers

1986 • 1,134 citations

Mesocorticolimbic dopaminergic network: functional and regulatory roles

1991 • 1,104 citations

Cocaine and Other Stimulants

1988 • 982 citations

The amygdalostriatal projection in the rat—an anatomical study by anterograde and retrograde tracing methods

1982 • 884 citations

Cocaine Addiction: Psychology and Neurophysiology

1991 • 753 citations

The distribution of the projection from the hippocampal formation to the nucleus accumbens in the rat: An anterograde and retrograde-horseradish peroxidase study

1982 • 741 citations

Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens

1980 • 736 citations

Selective 60HDA-induced destruction of mesolimbic dopamine neurons: Abolition of psychostimulant-induced locomotor activity in rats

1976 • 706 citations

Dopamine, schizophrenia, mania, and depression: Toward a unified hypothesis of cortico-striatopallido-thalamic function

1987 • 682 citations

Psychiatric Diagnoses of Treatment-Seeking Cocaine Abusers

1991 • 626 citations

Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats

1989 • 562 citations

Animal models of drug craving

1993 • 560 citations

A behavioral approach to achieving initial cocaine abstinence

1991 • 559 citations

The neurobiology of craving: Implications for the understanding and treatment of addiction.

1988 • 555 citations

Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide, but not with the noradrenergic blockers phentolamine or phenoxybenzamine.

1977 • 490 citations

Modulation of Cocaine Self-Administration in the Rat Through D-3 Dopamine Receptors

1993 • 452 citations

A Comparison of Male and Female Cocaine Abusers

1989 • 408 citations

Effects of chronic cocaine abuse on postsynaptic dopamine receptors

1990 • 407 citations

Neural projections from nucleus accumbens to globus pallidus, substantia innominata, and lateral preoptic-lateral hypothalamic area: an anatomical and electrophysiological investigation in the rat

1983 • 403 citations

Prognostic Significance of Psychopathology in Treated Opiate Addicts

1986 • 386 citations

Desipramine Facilitation of Initial Cocaine Abstinence

1989 • 371 citations

Psychotherapy and Pharmacotherapy for Ambulatory Cocaine Abusers

1994 • 349 citations

Sources of presumptive glutamergic/aspartergic afferents to the rat ventral striatopallidal region

1987 • 346 citations

Functions of dopamine in the dorsal and ventral striatum

1992 • 340 citations

Changes in Mood, Craving, and Sleep During Short-term Abstinence Reported by Male Cocaine Addicts

1990 • 284 citations

Fluoxetine reduces intravenous cocaine self-administration in rats

1990 • 254 citations

Disruption of cocaine and heroin self-administration following kainic acid lesions of the nucleus accumbens

1985 • 232 citations

Opium, Cocaine and Marijuana in American History

1991 • 224 citations

The ventral pallidum plays a role in mediating cocaine and heroin self-administration in the rat

1990 • 223 citations

Cocaine reinforcement and extracellular dopamine overflow in rat nucleus accumbens: an in vivo microdialysis study

1989 • 204 citations

Cocaine disposition in the brain after continuous or intermittent treatment and locomotor stimulation in mice.

1987 • 193 citations

Dopamine, addiction and reward

1992 • 179 citations

Clinical phenomenology and neurobiology of cocaine abstinence: a prospective inpatient study

1991 • 179 citations

Double-blind Comparison of Amantadine and Bromocriptine for Ambulatory Withdrawal From Cocaine Dependence

1987 • 175 citations

Epidemiology of Drug Abuse: An Overview

1986 • 159 citations

Neurochemical Correlates of Cocaine and Ethanol Self‐Administrationa

1992 • 156 citations

Atypical neuroleptics increase self-administration of cocaine: An evaluation of a behavioural screen for antipsychotic activity

1983 • 150 citations

Psychopathology among Cocaine Abusers Entering Treatment

1990 • 149 citations

Protracted elimination of cocaine metabolites in long-term, high-dose cocaine abusers

1988 • 143 citations

Outpatient Treatment of 'Crack' Cocaine Smoking With Flupenthixol Decanoate

1989 • 133 citations

Nucleus accumbens NMDA antagonist decreases locomotor activity produced by cocaine, heroin or accumbens dopamine, but not caffeine

1991 • 131 citations

Comparison of Amantadine and Desipramine Combined with Psychotherapy for Treatment of Cocaine Dependence

1991 • 128 citations

Comparison of the effects of cocaine and other inhibitors of dopamine uptake in rat striatum, nucleus accumbens, olfactory tubercle, and medial prefrontal cortex

1990 • 128 citations

Outcomes for cocaine abusers after once-a-week psychosocial therapy

1991 • 126 citations

NMDA receptors in the nucleus accumbens modulate intravenous cocaine but not heroin self-administration in the rat

1992 • 124 citations

Methylphenidate Treatment of Cocaine Abusers without Attention Deficit Disorder: A Negative Report

1985 • 119 citations

Methylphenidate (Ritalin®) treatment of cocaine dependence—A preliminary report

1984 • 119 citations

Neuroleptic reduction of cocaine-induced paranoia but not euphoria?

1986 • 115 citations

Substantia innominata: Critical link in the behavioral expression of mesolimbic dopamine stimulation in the rat

1984 • 115 citations

Single-dose bromocriptine reverses cocaine craving

1987 • 111 citations

Prolonged Occurrence of Cocaine In Human Saliva and Urine after Chronic Use

1989 • 108 citations

Treatment of Depression in Chronic Cocaine and Phencyclidine Abuse With Desipramine

1986 • 94 citations

Depression as a prognostic factor for pharmacological treatment of cocaine dependence.

1991 • 94 citations

Cocaine: Acute effects of reinforcement thresholds for self-stimulation behavior to the medial forebrain bundle

1978 • 90 citations

Pharmacological approaches to cocaine addiction

1985 • 90 citations

Opponent process and drug dependence: Neurobiological mechanisms

1993 • 89 citations

Antecedents and Consequences of Cocaine Abuse among Opioid Addicts

1988 • 87 citations

Regional neuroleptic microinjections indicate a role for nucleus accumbens in lateral hypothalamic self-stimulation reward

1989 • 85 citations

Lithium treatment for cocaine abusers with bipolar spectrum disorders

1990 • 69 citations

Chronic cocaine administration alters corticotropin-releasing factor receptors in the rat brain

1990 • 68 citations

Electrolytic lesions of the substantia innominata and lateral preoptic area attenuate the ‘supersensitive’ locomotor response to apomorphine resulting from denervation of the nucleus accumbens

1984 • 68 citations

Pharmacotherapeutic Interventions for Cocaine Abuse Matching Patients to Treatments

1989 • 63 citations

The effects of lisuride on mood and sleep during acute withdrawal in stimulant abusers: A preliminary report

1994 • 63 citations

Susceptibility to sensitization. II. The influence of gonadal hormones on enduring changes in brain monoamines and behavior produced by the repeated administration of d-amphetamine or restraint stress

1988 • 63 citations

Evaluation of TDx Cocaine Metabolite Assay

1987 • 61 citations

Prolonged presence of metabolite in urine after compulsive cocaine use.

1990 • 59 citations

Double-blind comparison of amantadine and bromocriptine for ambulatory withdrawal from cocaine dependence

1987 • 59 citations

Cocaine Abuse and Its Treatment

1990 • 57 citations

Effects of cocaine on dopamine receptor gene expression: A study in the postmortem human brain

1993 • 56 citations

Trazodone—Oral Cocaine Interactions

1984 • 52 citations

Crack/cocaine abusers in the general hospital: assessment and initiation of care

1992 • 47 citations

Cocaine reduction in unmotivated crack users using carbamazepine versus placebo in a short-term, double-blind crossover design

1991 • 46 citations

Cocaine: On-line analysis of an accumbens amine neural basis for psychomotor behavior

1991 • 46 citations

Double-blind evaluation of the effect of acute amantadine on cocaine craving

1989 • 45 citations

Chronic carbamazepine inhibits the development of local anesthetic seizures kindled by cocaine and lidocaine

1989 • 41 citations

Lisuride Reduces Psychomotor Retardation during Withdrawal from Chronic Intravenous Amphetamine Self-Administration in Rats

1993 • 41 citations

Effects of carbamazepine on acute responses to smoked cocaine-base in human cocaine users

1991 • 41 citations

Subpallidal-pedunculopontine projections but not subpallidal-mediodorsal thalamus projections contribute to spontaneous exploratory locomotor activity

1989 • 39 citations

Pergolide mesylate treatment of cocaine withdrawal.

1991 • 38 citations

Cocaine/"crack" dependence among psychiatric inpatients

1990 • 37 citations

Distinguishing effects of cocaine IV and SC on mesoaccumbens dopamine and serotonin release with chloral hydrate anesthesia

1992 • 36 citations

Psychological Approaches for the Treatment of Cocaine Dependence-A Neurobehavioral Approach

1992 • 35 citations

Pharmacotherapeutic Interventions for Cocaine Abuse:

1991 • 33 citations

Buprenorphine for cocaine and opiate dependence.

1992 • 32 citations

Role played by catechol and indolamines in the central actions of reserpine after monoaminoxidase inhibition

1965 • 29 citations

Cocaine

1990 • 25 citations

Cocaine Use, Risk Taking, and Fatal Russian Roulette

1992 • 23 citations

Relapse to cocaine abuse after initiating desipramine treatment

1988 • 22 citations

Pharmacologic approaches to the treatment of cocaine dependence.

1990 • 20 citations

Measuring Outcome in the Treatment of Cocaine Abuse:

1992 • 19 citations

A pilot trial of gepirone vs. placebo in the treatment of cocaine dependency.

1992 • 18 citations

Contributions to a Social Conditioning Model of Cocaine Recovery

1991 • 18 citations

An Open Trial of Maprotiline for the Treatment of Cocaine Abuse

1988 • 15 citations

Designing Drug Efficacy Trials in the Treatment of Cocaine Abuse

1991 • 12 citations

A Longitudinal Analysis of Factors Associated With Morbidity in Cocaine Abusers With Psychiatric Illness

1992 • 10 citations

From Ganja to Crack: Caribbean Participation in the Underground Economy in Brooklyn, 1976–1986. Part 2. Establishment of the Cocaine (and Crack) Economy

1991 • 9 citations

Refraining of an Addiction via Hypnotherapy: A Case Presentation

1991 • 9 citations

Quantitative urine testing

1989 • 8 citations

Cocaine use, risk taking, and fatal Russian roulette

1992 • 7 citations

Still Flying Blind in the War on Drugs

1990 • 4 citations

The pharmacologic treatment of alcohol and cocaine abuse. Integration of recent findings into clinical practice.

1992 • 3 citations

The Pharmacologic Treatment of Alcohol and Cocaine Abuse

1992 • 2 citations

Where Is the SSC Cost Estimate?

1990 • 1 citations

Deleted Work

1955 • 0 citations