Stromelysin-3 in stromal tissue as a control factor in breast cancer behavior

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

1991 • 5,657 citations

Tumors: Wounds That Do Not Heal

1986 • 4,202 citations

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

The matrix‐degrading metalloproteinases

1992 • 1,383 citations

The role of angiogenesis in tumor growth.

1992 • 1,267 citations

Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture.

1990 • 1,147 citations

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1990 • 1,140 citations

Cytokines in context.

1991 • 808 citations

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

1986 • 764 citations

Breast Cancer

1992 • 695 citations

Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells

1977 • 686 citations

Control of mammary epithelial differentiation: basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity.

1991 • 659 citations

Lobular neoplasia of the breast: Higher risk for subsequent invasive cancer predicted by more extensive disease

1991 • 429 citations

Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization.

1992 • 331 citations

M(r) 92,000 type IV collagenase is increased in plasma of patients with colon cancer and breast cancer.

1993 • 298 citations

Urokinase-plasminogen activator, a new and independent prognostic marker in breast cancer.

1990 • 294 citations

Tumour progression and the nature of cancer

1991 • 273 citations

Prognostic value of urokinase-type plasminogen activator in 671 primary breast cancer patients.

1992 • 239 citations

Stromal Involvement In Malignant Growth

1988 • 225 citations

Increased stromelysin 3 gene expression is associated with increased local invasiveness in head and neck squamous cell carcinomas.

1993 • 222 citations

Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression.

1993 • 209 citations

The matrix metalloproteinases and their natural inhibitors: prospects for treating degenerative tissue diseases

1992 • 190 citations

The origin of matrix metalloproteinases and their familial relationships

1991 • 182 citations

Localization of urokinase-type plasminogen activator in stromal cells in adenocarcinomas of the colon in humans.

1991 • 179 citations

The breast cancer-associated stromelysin-3 gene is expressed during mouse mammary gland apoptosis.

1992 • 173 citations

Effects of inhibition of basement membrane collagen deposition on rat mammary gland development

1980 • 169 citations

The 28-kDa N-terminal domain of mouse stromelysin-3 has the general properties of a weak metalloproteinase

1993 • 132 citations

Correlation of serum metalloproteinase levels with lung cancer metastasis and response to therapy.

1992 • 129 citations

Extracellular matrix regulation of growth factor and protease activity

1991 • 128 citations

Breast-Cancer-Associated Stromelysin-3 Gene Is Expressed in Basal Cell Carcinoma and During Cutaneous Wound Healing

1992 • 127 citations

Expression of the stromelysin-3 gene in fibroblastic cells of invasive carcinomas of the breast and other human tissues: a review

1993 • 123 citations

Detection and localization of mRNAs encoding matrix metalloproteinases and their tissue inhibitor in human breast pathology.

1993 • 115 citations

Extracellular matrix as a solid-state regulator in angiogenesis: identification of new targets for anti-cancer therapy.

1992 • 113 citations

Differential protease expression by cutaneous squamous and basal cell carcinomas.

1991 • 95 citations

Detection of mRNAs encoding collagenase I and stromelysin 2 in carcinomas of the head and neck by in situ hybridization.

1991 • 88 citations

The molecular biology of breast cancer

1991 • 74 citations

Expression of 92-kDa Type IV Collagenase mRNA by Eosinophils Associated with Basal Cell Carcinoma

1992 • 67 citations

Extracellular proteases and embryonic pattern formation

1992 • 62 citations

The Development of Biological Therapies for Breast Cancer

1993 • 49 citations

Importance of orthotopic transplantation procedures in assessing the effects of transfected genes on human tumor growth and metastasis

1991 • 45 citations

Basal Cell Carcinoma and Collagenase

1986 • 40 citations

Expression of activated oncogenes in the murine mammary gland: transgenic models for human breast cancer

1991 • 31 citations

The role of stromal cells in tumor metastasis: a new link.

1991 • 27 citations

New developments in in vivo models of neoplasia

1991 • 12 citations