Physiology, structure, and regulation of the cloned organic anion transporters

Functional rafts in cell membranes

1997 • 9,471 citations

A JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

1909 • 6,516 citations

Pharmacological Reviews

2024 • 2,716 citations

Molecular identification of a renal urate–anion exchanger that regulates blood urate levels

2002 • 1,411 citations

Structure and Mechanism of the Lactose Permease of Escherichia coli

2003 • 1,369 citations

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

2012 • 1,196 citations

Structure and Mechanism of the Glycerol-3-Phosphate Transporter from Escherichia coli

2003 • 987 citations

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

2004 • 976 citations

The superfamily of organic anion transporting polypeptides

2002 • 859 citations

Drug excretion mediated by a new prototype of polyspecific transporter

1994 • 637 citations

Expression Cloning and Characterization of a Novel Multispecific Organic Anion Transporter

1997 • 619 citations

Molecular interactions with mercury in the kidney.

2000 • 617 citations

Expression of Thirty-six Drug Transporter Genes in Human Intestine, Liver, Kidney, and Organotypic Cell Lines

2007 • 574 citations

Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: Drug–drug interactions and interindividual differences in transporter and metabolic enzyme functions

2006 • 559 citations

The SLC22 drug transporter family

2004 • 519 citations

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: Consequences for pravastatin pharmacokinetics

2003 • 514 citations

Identification and Characterization of Human Organic Anion Transporter 3 Expressing Predominantly in the Kidney

2001 • 501 citations

Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain

1999 • 486 citations

Mechanisms mediating renal secretion of organic anions and cations

1993 • 484 citations

Transporters as a determinant of drug clearance and tissue distribution

2006 • 482 citations

THE MEASUREMENT OF THE TUBULAR EXCRETORY MASS, EFFECTIVE BLOOD FLOW AND FILTRATION RATE IN THE NORMAL HUMAN KIDNEY

1938 • 432 citations

Expression Cloning and Characterization of ROAT1

1997 • 428 citations

RENAL TUBULAR TRANSPORT: ACCUMULATION OF P-AMINOHIPPURATE BY RABBIT KIDNEY SLICES

1950 • 407 citations

Molecular Cloning and Characterization of Multispecific Organic Anion Transporter 4 Expressed in the Placenta

2000 • 405 citations

Molecular and Cellular Physiology of Renal Organic Cation and Anion Transport

2004 • 404 citations

Structure, Function, Expression, Genomic Organization, and Single Nucleotide Polymorphisms of Human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) Efflux Transporters

2006 • 395 citations

Clinical and Molecular Analysis of Patients with Renal Hypouricemia in Japan-Influence of URAT1 Gene on Urinary Urate Excretion

2004 • 375 citations

Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney

1999 • 362 citations

The Antiviral Nucleotide Analogs Cidofovir and Adefovir Are Novel Substrates for Human and Rat Renal Organic Anion Transporter 1

1999 • 345 citations

Identification of multispecific organic anion transporter 2 expressed predominantly in the liver

1998 • 339 citations

Molecular Physiology of Urate Transport

2005 • 336 citations

Protein Kinase Czeta (PKCzeta): Activation Mechanisms and Cellular Functions

2003 • 301 citations

Transport of organic anions across the basolateral membrane of proximal tubule cells

2003 • 297 citations

Structure of renal organic anion and cation transporters

2000 • 296 citations

Impaired Organic Anion Transport in Kidney and Choroid Plexus of Organic Anion Transporter 3 (Oat3 (Slc22a8)) Knockout Mice

2002 • 284 citations

Transporters involved in the elimination of drugs in the kidney: Organic anion transporters and organic cation transporters

2001 • 276 citations

Human Organic Anion Transporters and Human Organic Cation Transporters Mediate Renal Antiviral Transport

2002 • 274 citations

Organic Anion Transporters of the SLC22 Family: Biopharmaceutical, Physiological, and Pathological Roles

2007 • 271 citations

Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: A resource for investigations into drug disposition

2006 • 264 citations

Molecular Cloning and Characterization of NKT, a Gene Product Related to the Organic Cation Transporter Family That Is Almost Exclusively Expressed in the Kidney

1997 • 256 citations

Regulation of renal urate excretion: A critical review

1998 • 251 citations

Characterization of Methotrexate Transport and Its Drug Interactions with Human Organic Anion Transporters

2002 • 250 citations

Decreased Renal Organic Anion Secretion and Plasma Accumulation of Endogenous Organic Anions in OAT1 Knock-out Mice

2005 • 223 citations

Gender differences in kidney function

2007 • 218 citations

Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na⁺gradient

2003 • 218 citations

Molecular cloning and characterization of a novel liver-specific transport protein

1994 • 216 citations

Human Organic Anion Transporter 4 Is a Renal Apical Organic Anion/Dicarboxylate Exchanger in the Proximal Tubules

2004 • 213 citations

Organic Anion Transporter Family: Current Knowledge

2006 • 208 citations

Isolation of a Family of Organic Anion Transporters from Human Liver and Kidney

2001 • 202 citations

Interactions of Human Organic Anion Transporters with Diuretics

2003 • 191 citations

VEGF expression in an osteoblast-like cell line is regulated by a hypoxia response mechanism

2000 • 191 citations

The Multivalent PDZ Domain-containing Protein PDZK1 Regulates Transport Activity of Renal Urate-Anion Exchanger URAT1 via Its C Terminus

2004 • 188 citations

Interaction of Human Organic Anion Transporters 2 and 4 with Organic Anion Transport Inhibitors

2002 • 187 citations

Gender-Specific and Developmental Influences on the Expression of Rat Organic Anion Transporters

2002 • 185 citations

Interactions of Human Organic Anion Transporters and Human Organic Cation Transporters with Nonsteroidal Anti-Inflammatory Drugs

2002 • 184 citations

New insights into renal transport of urate

2007 • 179 citations

Human Organic Anion Transporters and Human Organic Cation Transporters Mediate Renal Transport of Prostaglandins

2002 • 178 citations

Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier.

2001 • 178 citations

Regulation of Hepatic Transporters by Xenobiotic Receptors

2005 • 177 citations

Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition

2004 • 173 citations

Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C

1999 • 171 citations

Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease

2005 • 170 citations

Characterization and identification of steroid sulfate transporters of human placenta

2003 • 169 citations

Molecular Cloning and Characterization of Two Novel Human Renal Organic Anion Transporters (hOAT1 and hOAT3)

1999 • 167 citations

Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7])

2005 • 164 citations

Expression cloning and characterization of a renal organic anion transporter from winter flounder

1997 • 163 citations

Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups*

2003 • 162 citations

Human Organic Anion Transporter 3 (hOAT3) can Operate as an Exchanger and Mediate Secretory Urate Flux

2003 • 160 citations

Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.

1999 • 154 citations

Function and Localization of Urate Transporter 1 in Mouse Kidney

2004 • 153 citations

Organic anion transporter (Slc22a) family members as mediators of toxicity

2004 • 149 citations

Role of human organic anion transporter 4 in the transport of ochratoxin A

2002 • 148 citations

Human Vascular Smooth Muscle Cells Express a Urate Transporter

2006 • 145 citations

Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C)

2004 • 145 citations

Association of the human urate transporter 1 with reduced renal uric acid excretion and hyperuricemia in a German Caucasian population

2005 • 142 citations

Indirect coupling to Na+ of p-aminohippuric acid uptake into rat renal basolateral membrane vesicles

1987 • 142 citations

Functional Involvement of Rat Organic Anion Transporter 3 (rOat3;Slc22a8) in the Renal Uptake of Organic Anions

2002 • 141 citations

Amino Acids Critical for Substrate Affinity of Rat Organic Cation Transporter 1 Line the Substrate Binding Region in a Model Derived from the Tertiary Structure of Lactose Permease

2005 • 140 citations

Renal Transporters for Organic Anions and Organic Cations. Structural Requirements for Substrates

1997 • 139 citations

Functional characterization of the rat multispecific organic anion transporter OAT1 mediating basolateral uptake of anionic drugs in the kidney

1998 • 139 citations

Urate transport via human PAH transporter hOAT1 and its gene structure

2003 • 138 citations

Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate

2007 • 130 citations

The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1.

1999 • 127 citations

Relationship between cholesterol trafficking and signaling in rafts and caveolae

2003 • 126 citations

Role of Glycosylation in the Organic Anion Transporter OAT1

2004 • 126 citations

Pharmacogenomics of the OATP and OAT Families

2004 • 126 citations

Olfactory uptake of manganese requires DMT1 and is enhanced by anemia

2006 • 124 citations

Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney

2004 • 123 citations

The Role of N-Linked Glycosylation in Protein Folding, Membrane Targeting, and Substrate Binding of Human Organic Anion Transporter hOAT4

2004 • 120 citations

Functional Consequences of Single Nucleotide Polymorphisms in the Human Organic Anion Transporter hOAT1 (SLC22A6)

2005 • 118 citations

Contraluminal transport systems in the proximal renal tubule involved in secretion of organic anions

1988 • 115 citations

Interaction of human organic anion transporters with various cephalosporin antibiotics

2002 • 113 citations

Contribution of Organic Anion Transporter 3 (Slc22a8) to the Elimination of p-Aminohippuric Acid and Benzylpenicillin across the Blood-Brain Barrier

2003 • 113 citations

Drug Metabolism Reviews

1975 • 112 citations

Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct

2000 • 111 citations

Organic anion and cation transporters occur in pairs of similar and similarly expressed genes

2003 • 110 citations

Coupled transport of p-aminohippurate by rat kidney basolateral membrane vesicles

1988 • 108 citations

Modulation of Renal Apical Organic Anion Transporter 4 Function by Two PDZ Domain–Containing Proteins

2005 • 105 citations

Homocysteine and the Renal Epithelial Transport and Toxicity of Inorganic Mercury

2004 • 104 citations

Renal expression of organic anion transporter OAT2 in rats and mice is regulated by sex hormones

2006 • 104 citations

Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1)

2005 • 102 citations

Cloning of a Human Renal p–Aminohippurate Transporter, hROAT1

1998 • 101 citations

The human organic anion transporter 3 (OAT3;SLC22A8): genetic variation and functional genomics

2005 • 100 citations

Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa

2004 • 99 citations

The lactose permease of Escherichia coli: overall structure, the sugar‐binding site and the alternating access model for transport

2003 • 98 citations

Human Organic Anion Transporters Mediate the Transport of Tetracycline

2002 • 95 citations

Molecular Pharmacology

2012 • 92 citations

Analyses of coding region polymorphisms in apical and basolateral human organic anion transporter (OAT) genes [OAT1 (NKT), OAT2, OAT3, OAT4, URAT (RST)] Rapid Communication

2005 • 92 citations

Regulation of mOAT-mediated Organic Anion Transport by Okadaic Acid and Protein Kinase C in LLC-PK1 Cells

2000 • 92 citations

Regulation of the Expression of Human Organic Anion Transporter 3 by Hepatocyte Nuclear Factor 1α/β and DNA Methylation

2006 • 91 citations

Interaction of ochratoxin A with human intestinal Caco-2 cells: possible implication of a multidrug resistance-associated protein (MRP2)

2003 • 91 citations

Catalog of 258 single-nucleotide polymorphisms (SNPs) in genes encoding three organic anion transporters, three organic anion-transporting polypeptides, and three NADH:ubiquinone oxidoreductase flavoproteins

2001 • 91 citations

Functional characterization of rat organic anion transporter 2 in LLC-PK1 cells.

2001 • 91 citations

Molecular Insights into the Structure–Function Relationship of Organic Anion Transporters OATs

2006 • 90 citations

Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites

2005 • 90 citations

New Aspects of the Blood-Brain Barrier Transporters; Its Physiological Roles in the Central Nervous System

2004 • 90 citations

Isolation, Characterization and Differential Gene Expression of Multispecific Organic Anion Transporter 2 in Mice

2002 • 88 citations

Structural Variation Governs Substrate Specificity for Organic Anion Transporter (OAT) Homologs

2007 • 87 citations

Human Renal Organic Anion Transporter 1-Dependent Uptake and Toxicity of Mercuric-Thiol Conjugates in Madin-Darby Canine Kidney Cells

2003 • 87 citations

Human renal organic anion transporters: Characteristics and contributions to drug and drug metabolite excretion

2005 • 85 citations

Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family

2007 • 84 citations

Protein Kinase C Activation Downregulates Human Organic Anion Transporter 1-Mediated Transport through Carrier Internalization

2003 • 83 citations

Functional Characterization of Rat Organic Anion Transporter 5 (Slc22a19) at the Apical Membrane of Renal Proximal Tubules

2005 • 83 citations

The W258X mutation in SLC22A12 is the predominant cause of Japanese renal hypouricemia

2004 • 81 citations

A Three-dimensional Model of Human Organic Anion Transporter 1

2006 • 81 citations

A Novel Putative Transporter Maps to the Osteosclerosis (oc) Mutation and Is Not Expressed in theocMutant Mouse

1999 • 80 citations

Kidney‐specific expression of a novel mouse organic cation transporter‐like protein

1997 • 80 citations

Interactions of human organic anion as well as cation transporters with indoxyl sulfate

2003 • 79 citations

Importance of Hepatic Induction of Constitutive Androstane Receptor and Other Transcription Factors That Regulate Xenobiotic Metabolism and Transport

2007 • 79 citations

Mutational analysis of idiopathic renal hypouricemia in Korea

2005 • 78 citations

The Human Organic Anion Transporter 2 Gene Is Transactivated by Hepatocyte Nuclear Factor-4α and Suppressed by Bile Acids

2005 • 78 citations

The molecular and cellular physiology of basolateral organic anion transport in mammalian renal tubules

2003 • 77 citations

Mouse Reduced in Osteosclerosis Transporter Functions as an Organic Anion Transporter 3 and Is Localized at Abluminal Membrane of Blood-Brain Barrier

2004 • 76 citations

Heterologous Expression and Functional Characterization of a Mouse Renal Organic Anion Transporter in Mammalian Cells

1999 • 76 citations

Molecular Cloning and Functional Analyses of OAT1 and OAT3 from Cynomolgus Monkey Kidney

2005 • 76 citations

Arginine 454 and Lysine 370 Are Essential for the Anion Specificity of the Organic Anion Transporter, rOAT3

2001 • 74 citations

A Conserved Glutamate Residue in Transmembrane Helix 10 Influences Substrate Specificity of Rabbit OCT2 (SLC22A2)

2005 • 71 citations

Transcriptional Regulation of Human and Mouse Organic Anion Transporter 1 by Hepatocyte Nuclear Factor 1 α/β

2007 • 69 citations

Regulation of Tissue-Specific Expression of the Human and Mouse Urate Transporter 1 Gene by Hepatocyte Nuclear Factor 1 α/β and DNA Methylation

2007 • 66 citations

Anion transport through the contraluminal cell membrane of renal proximal tubule. The influence of hydrophobicity and molecular charge distribution on the inhibitory activity of organic anions

1989 • 65 citations

Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions

2006 • 65 citations

Regulation by protein kinase C of organic anion transport driven by rat organic anion transporter 3 (rOAT3)

2000 • 63 citations

Regulation of renal tubular secretion of organic compounds

2001 • 63 citations

Renal organic anion transport: a comparative and cellular perspective

2002 • 63 citations

Transport of Xenobiotics Across the Blood-Brain Barrier

2002 • 62 citations

The function of the proximal convoluted segment of the renal tubule

1932 • 60 citations

Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice

2004 • 59 citations

AN EXPERIMENTAL AND CLINICAL STUDY OF THE FUNCTIONAL ACTIVITY OF THE KIDNEYS BY MEANS OF PHENOLSULPHONEPHTHALEIN

1910 • 58 citations

Hepatocyte nuclear factor-4α regulates the human organic anion transporter 1 gene in the kidney

2007 • 57 citations

Molecular Physiology of Renalp-Aminohippurate Secretion

2001 • 57 citations

Influence of Sex Differences on the Renal Secretion of Organic Anions

1998 • 57 citations

Sex differences in p-aminohippuric acid transport in rat kidney: role of membrane fluidity and expression of OAT1.

2002 • 56 citations

Sex Differences in the mRNA, Protein, and Functional Expression of Organic Anion Transporter (Oat) 1, Oat3, and Organic Cation Transporter (Oct) 2 in Rabbit Renal Proximal Tubules

2005 • 56 citations

A common mutation in an organic anion transporter gene, SLC22A12, is a suppressing factor for the development of gout

2005 • 56 citations

Luminal and peritubular steps in renal transport of

1987 • 55 citations

Mutations in Human Urate Transporter 1 Gene in Presecretory Reabsorption Defect Type of Familial Renal Hypouricemia

2005 • 55 citations

Genomic Structure and in Vivo Expression of the Human Organic Anion Transporter 1 (hOAT1) Gene

2000 • 54 citations

Sphingolipid trafficking and protein sorting in epithelial cells

2002 • 54 citations

THE DIETARY POLYPHENOL ELLAGIC ACID IS A POTENT INHIBITOR OF hOAT1

2005 • 54 citations

Rat renal cortical slices demonstrate p-aminohippurate/glutarate exchange and sodium/glutarate coupled p-aminohippurate transport.

1990 • 53 citations

Acute regulation of OAT3-mediated estrone sulfate transport in isolated rabbit renal proximal tubules

2004 • 51 citations

Prostaglandin E2 Inhibits Its Own Renal Transport by Downregulation of Organic Anion Transporters rOAT1 and rOAT3

2005 • 51 citations

Interaction of the Metal Chelator 2,3-Dimercapto-1-propanesulfonate with the Rabbit Multispecific Organic Anion Transporter 1 (rbOAT1)

2002 • 51 citations

Presence of organic anion transporters 3 (OAT3) and 4 (OAT4) in human adrenocortical cells

2004 • 49 citations

Factors influencing renal excretion of foreign organic acids

1964 • 48 citations

Critical Amino Acid Residues in Transmembrane Domain 1 of the Human Organic Anion Transporter hOAT1

2004 • 48 citations

Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20)

2006 • 47 citations

The Chloride Dependence of the Human Organic Anion Transporter 1 (hOAT1) Is Blunted by Mutation of a Single Amino Acid

2007 • 45 citations

Regulation of human organic anion transporter 4 by progesterone and protein kinase C in human placental BeWo cells

2007 • 43 citations

Handling of cysteine S-conjugates of methylmercury in MDCK cells expressing human OAT1

2005 • 43 citations

The Impact of Plasma Protein Binding on the Renal Transport of Organic Anions

2005 • 43 citations

RENAL TRANSPORT OF ORGANIC COMPOUNDS MEDIATED BY MOUSE ORGANIC ANION TRANSPORTER 3 (MOAT3): FURTHER SUBSTRATE SPECIFICITY OF MOAT3

2004 • 41 citations

Analyses of 5′ regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3)

2006 • 41 citations

Cationic Amino Acids Involved in Dicarboxylate Binding of the Flounder Renal Organic Anion Transporter

2001 • 41 citations

The Blood-Cerebrospinal Fluid Barrier

2005 • 41 citations

Towards an understanding of organic anion transporters: Structure-function relationships

2004 • 40 citations

Localization of an organic anion transporter-GFP fusion construct (rROAT1-GFP) in intact proximal tubules

1999 • 39 citations

Co-localization and interaction of organic anion transporter 1 with caveolin-2 in rat kidney

2005 • 38 citations

Characterization of the mechanisms involved in the gender differences inp-aminohippurate renal elimination in rats

2001 • 38 citations

Interaction of 2,3-dimercapto-1-propane sulfonate with the human organic anion transporter hOAT1.

2001 • 38 citations

PKC regulation of organic anion secretion in perfused S2 segments of rabbit proximal tubules

2000 • 38 citations

Human Organic Anion Transporter 3 Gene Is Regulated Constitutively and Inducibly via a cAMP-Response Element

2006 • 37 citations

The Role of Glycine Residues in the Function of Human Organic Anion Transporter 4

2004 • 37 citations

p-Aminohippurate/2-oxoglutarate exchange in bovine renal brush-border and basolateral membrane vesicles

1993 • 36 citations

Cysteine residues in the organic anion transporter mOAT1

2004 • 35 citations

Differences in the inhibition of cytochromes P450 3A4 and 3A5 by metabolite-inhibitor complex-forming drugs.

2004 • 35 citations

Inhibition of initial transport rate of basolateral organic anion carrier in renal PT by BK and phenylephrine

1999 • 35 citations

Role of Aromatic Transmembrane Residues of the Organic Anion Transporter, rOAT3, in Substrate Recognition

2002 • 34 citations

Comparison of the Interaction of Human Organic Anion Transporter hOAT4 with PDZ Proteins between Kidney Cells and Placental Cells

2007 • 34 citations

Short-Term Regulation of Basolateral Organic Anion Uptake in Proximal Tubular OK cells

2002 • 34 citations

Uric Acid and the Kidney: Urate Transport, Stone Disease and Progressive Renal Failure

2005 • 34 citations

Short-Term Regulation of Basolateral Organic Anion Uptake in Proximal Tubular Opossum Kidney Cells

2003 • 34 citations

Cloning of the pig renal organic anion transporter 1 (pOAT1)

2002 • 33 citations

Effects of gender on the pharmacokinetics of drugs secreted by the renal organic anions transport systems in the rat

2002 • 32 citations

Characterization of mouse organic anion transporter 5 as a renal steroid sulfate transporter

2005 • 32 citations

Molecular cloning and functional characterization of a polyspecific organic anion transporter from Caenorhabditis elegans.

1999 • 32 citations

Solubilization and Preformulation Studies on PG-300995 (An Anti-HIV Drug)

2004 • 30 citations

The flounder organic anion transporter fOat has sequence, function, and substrate specificity similarity to both mammalian Oat1 and Oat3

2006 • 25 citations

Mouse organic anion transporter 2 and 3 (mOAT2/3[Slc22a7/8]) mediates the renal transport of bumetanide

2005 • 23 citations

Mutational analysis of histidine residues in human organic anion transporter 4 (hOAT4)

2004 • 22 citations

The Putative Transmembrane Segment 7 of Human Organic Anion Transporter hOAT1 Dictates Transporter Substrate Binding and Stability

2006 • 22 citations

Influence of albumin binding on the substrate transport mediated by human hepatocyte transporters OATP2 and OATP8

2003 • 21 citations

CHARACTERIZATION OF THE RENAL TUBULAR TRANSPORT OF ZONAMPANEL, A NOVEL α-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID RECEPTOR ANTAGONIST, BY HUMAN ORGANIC ANION TRANSPORTERS

2004 • 19 citations

Functional expression of pig renal organic anion transporter 3 (pOAT3)

2005 • 19 citations

Confocal imaging of xenobiotic transport across the blood‐brain barrier

2003 • 18 citations

Functional Role of the C Terminus of Human Organic Anion Transporter hOAT1

2006 • 18 citations

Determination of the external loops and the cellular orientation of the N- and the C-termini of the human organic anion transporter hOAT1

2006 • 17 citations

Characterization of the mechanisms involved in the gender differences in <i>p</i>-aminohippurate renal elimination in rats

2001 • 17 citations

Evidence for Rat Organic Anion Transporter 3 Association with Caveolin‐1 in Rat Kidney

2005 • 16 citations

Expression systems for cloned xenobiotic transporters

2005 • 14 citations

Directing Role of Organic Anion Transporters in the Excretion of Mercapturic Acids of Alkylated Polycyclic Aromatic Hydrocarbons

2007 • 10 citations

Relevance of Atypical Protein Kinase C Isotypes to the Drug Discovery Process

2005 • 5 citations

Functional characterization of human organic anion transporter 4 (hOAT4) in a Baculovirus expression system

2007 • 2 citations

Molecular basis for the differential sensitivity of OCT2 and OAT1 toward Hg ²⁺

2007 • 1 citations

Deleted Work

1955 • 0 citations