Neurotoxic and neuroprotective effects of glutamate are enhanced by introduction of amyloid precursor protein cDNA

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1994 • 3,437 citations

Ionic dependence of glutamate neurotoxicity

1987 • 1,811 citations

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

1997 • 991 citations

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein

1993 • 800 citations

Kinesin Superfamily Motor Protein KIF17 and mLin-10 in NMDA Receptor-Containing Vesicle Transport

2000 • 700 citations

Interaction of Cytosolic Adaptor Proteins with Neuronal Apolipoprotein E Receptors and the Amyloid Precursor Protein

1998 • 544 citations

Secreted form of amyloid β protein precursor is involved in the growth regulation of fibroblasts

1989 • 477 citations

N-methyl-d-aspartate promotes the survival of cerebellar granule cells in culture

1988 • 437 citations

Activation of K+ channels and suppression of neuronal activity by secreted β-amyloid-precursor protein

1996 • 336 citations

Delayed neurotoxicity of excitatory amino acids In vitro

1987 • 332 citations

Cell-surface beta-amyloid precursor protein stimulates neurite outgrowth of hippocampal neurons in an isoform-dependent manner

1995 • 196 citations

Identification of an Evolutionarily Conserved Heterotrimeric Protein Complex Involved in Protein Targeting

1998 • 193 citations

Neuronal death in vitro: parallelism between survivability of hippocampal neurones and sustained elevation of cytosolic Ca2+ after exposure to glutamate receptor agonist

1988 • 178 citations

Interaction of a Neuron-specific Protein Containing PDZ Domains with Alzheimer's Amyloid Precursor Protein

1999 • 146 citations

The expression of amyloid beta protein precursor protects nerve cells from β-amyloid and glutamate toxicity and alters their interaction with the extracellular matrix

1993 • 130 citations

Increase in extracellular NCAM and amyloid precursor protein following induction of long-term potentiation in the dentate gyrus of anaesthetized rats

1994 • 125 citations

APP-BP1, a Novel Protein That Binds to the Carboxyl-terminal Region of the Amyloid Precursor Protein

1996 • 118 citations

Neurotrophic effects of NMDA receptor activation on developing cerebellar granule cells

1993 • 106 citations

A Labile Component of AMPA Receptor-Mediated Synaptic Transmission Is Dependent on Microtubule Motors, Actin, andN-Ethylmaleimide-Sensitive Factor

2001 • 95 citations

Secreted Form of Amyloid Precursor Protein Enhances Basal Glucose and Glutamate Transport and Protects Against Oxidative Impairment of Glucose and Glutamate Transport in Synaptosomes by a Cyclic GMP‐Mediated Mechanism

1999 • 94 citations

Localization of amyloid precursor protein in selective postsynaptic densities of rat cortical neurons

1992 • 70 citations

AMPA receptors in cerebellar granule cells during development in culture

1995 • 37 citations

Hemisynaptic distribution patterns of presenilins and ?-APP isoforms in the rodent cerebellum and hippocampus

2000 • 20 citations

Activity-dependent survival of rat cerebellar granule neurons is not associated with sustained elevation of intracellular Ca2+

1997 • 15 citations

Glutamate responsiveness enhanced in neurones expressing amyloid precursor protein

1997 • 14 citations

Activity-dependent survival and enhanced turnover of calcium in cultured rat cerebellar granule neurons

1998 • 13 citations