Secreted form of amyloid β protein precursor is involved in the growth regulation of fibroblasts

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects

1968 • 4,041 citations

Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus

1987 • 1,589 citations

Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's Disease

1987 • 1,316 citations

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1988 • 1,098 citations

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1988 • 1,093 citations

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1988 • 1,052 citations

Transcription and Translation — A Practical Approach

1985 • 811 citations

An unwinding activity that covalently modifies its double-stranded RNA substrate

1988 • 702 citations

Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides.

1987 • 589 citations

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

1988 • 584 citations

Amyloid β Protein Enhances the Survival of Hippocampal Neurons in Vitro

1989 • 470 citations

THE ROLE OF ANTISENSE RNA IN GENE REGULATION

1986 • 456 citations

Translational control of IS10 transposition

1983 • 362 citations

Amyloid Protein Precursor Messenger RNAs: Differential Expression in Alzheimer's Disease

1988 • 254 citations

Antisense RNA: its functions and applications in gene regulation — a review

1988 • 230 citations

Characterization of an amyloid beta precursor protein that binds heparin and contains tyrosine sulfate.

1989 • 196 citations

Amyloid β Protein Precursor Is Possibly a Heparan Sulfate Proteoglycan Core Protein

1988 • 189 citations

In situ hybridization of nucleus basalis neurons shows increased beta-amyloid mRNA in Alzheimer disease.

1988 • 186 citations

Conversion of Normal Behavior to Shiverer by Myelin Basic Protein Antisense cDNA in Transgenic Mice

1988 • 182 citations

Novel Neurotrophic Factors, Receptors, and Oncogenes

1989 • 152 citations

Three types of amyloid protein precursor mRNA in human brain: Their differential expression in Alzheimer's disease

1988 • 150 citations

Inhibition of rabbit globin mRNA translation by sequence-specific oligodeoxyribonucleotides

1985 • 115 citations

Alzheimer's disease brain extract stimulates the survival of cerebral cortical neurons from neonatal rats

1988 • 111 citations

Alzheimer's Disease and Related Conditions

1971 • 89 citations

Molecular cloning and characterization of a cDNA encoding the cerebrovascular and neuritic plaque amyloid peptides

1988 • 87 citations

Decreased adhesiveness of alzheimer's disease fibroblasts: Is amyloid β‐protein precursor involved?

1989 • 79 citations

Protease nexins: Cell‐secreted proteins that mediate the binding, internalization, and degradation of regulatory serine proteases

1983 • 66 citations

The inhibition of neunte outgrowth in PC12 cells by tubulin antisense oligodeoxyribonucleotides

1988 • 63 citations

Immunohistochemical evidence for the derivation of a peptide ligand from the amyloid beta-protein precursor of Alzheimer disease.

1988 • 56 citations

An antiserum against amyloid β-protein precursor detects a unique peptide in Alzheimer brain

1989 • 53 citations

Expression of the human papillomavirus type 18 E7 gene by a cassette-vector system for the transcription and translation of open reading frames in eukaryotic cells.

1987 • 36 citations

Recombination within the upstream gene of duplicated myelin basic protein genes of myelin deficient shimld mouse results in the production of antisense RNA.

1988 • 33 citations

IncreasedM_r60,000 Protein Phosphorylation is Correlated with Neocortical Neurofibrillary Tangles in Alzheimer's Disease

1988 • 16 citations