A cell cycle and mutational analysis of anchorage-independent growth: cell adhesion and TGF-beta 1 control G1/S transit specifically

The p53 tumour suppressor gene

1991 • 3,871 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

G ₁ Events and Regulation of Cell Proliferation

1989 • 2,203 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

1985 • 1,596 citations

E2F: a Link Between the Rb Tumor Suppressor Protein and Viral Oncoproteins

1992 • 1,552 citations

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

1992 • 1,071 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

1989 • 931 citations

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

1981 • 925 citations

Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation

1990 • 812 citations

Activation of cdc2 protein kinase during mitosis in human cells: Cell cycle-dependent phosphorylation and subunit rearrangement

1988 • 786 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro.

1975 • 747 citations

Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins.

1991 • 713 citations

Cyclins and cancer

1991 • 701 citations

Induction of DNA synthesis in BALB/c 3T3 cells by serum components: Reevaluation of the commitment process

1977 • 695 citations

TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains

1990 • 612 citations

Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein.

1991 • 578 citations

Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation.

1990 • 397 citations

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2.

1990 • 353 citations

The control of mRNA production, translation and turnover in suspended and reattached anchorage-dependent fibroblasts

1978 • 293 citations

Synthesis of labile, serum-dependent protein in early G ₁ controls animal cell growth

1979 • 273 citations

Control of intracellular pH and growth by fibronectin in capillary endothelial cells.

1990 • 241 citations

TGF‐β Receptors and TGF‐β Binding Proteoglycans: Recent Progress in Identifying Their Functional Properties

1990 • 233 citations

Transforming growth factor beta 1 inhibition of p34cdc2 phosphorylation and histone H1 kinase activity is associated with G1/S-phase growth arrest.

1991 • 203 citations

Induction of fibronectin gene transcription and mRNA is a primary response to growth-factor stimulation of AKR-2B cells.

1988 • 193 citations

Simple and Complex Cell Cycles

1989 • 192 citations

Cell adhesion induces expression of growth-associated genes in suspension-arrested fibroblasts.

1988 • 174 citations

G1/S control of anchorage-independent growth in the fibroblast cell cycle.

1991 • 120 citations

Exponential 3T3 cells escape in mid-G1 from their high serum requirement

1978 • 104 citations

Arrest of 3T3 cells in G1 phase in suspension culture

1976 • 96 citations

Differential effects of epidermal growth factor, transforming growth factor, and insulin on DNA and protein synthesis and morphology in serum-free cultures of AKR-2B cells.

1984 • 93 citations

Properties of mammalian cells transformed by temperature-sensitive mutants of avian sarcoma virus

1977 • 78 citations

Chapter 2 Induction and Isolation of Auxotrophic Mutants in Mammalian Cells

1974 • 66 citations

Cell attachment controls fibronectin and alpha 5 beta 1 integrin levels in fibroblasts. Implications for anchorage-dependent and -independent growth.

1992 • 65 citations

[32] Soft agar growth assays for transforming growth factors and mitogenic peptides

1987 • 49 citations

Transforming Growth Factor β1 Inhibition of p34^cdc2 Phosphorylation and Histone H1 Kinase Activity Is Associated with G1/S-Phase Growth Arrest

1991 • 31 citations

An anchorage-dependent locus in the cell cycle for the growth of 3T3 cells

1981 • 24 citations

Partial characterization of the mitogenic action of pp60^v‐src, the oncogenic protein product of the src gene of avian sarcoma virus

1984 • 21 citations

A preparative suspension culture system permitting quantitation of anchorage-independent growth by direct radiolabeling of cellular DNA

1989 • 18 citations

Cell Type Specificity of TGF‐β Binding

1990 • 18 citations

Induction of anchorage-independent growth by epidermal growth factor and altered sensitivity to type beta transforming growth factor in partially transformed rat kidney cells.

1986 • 12 citations