Synergy between encephalitogenic T cells and myelin basic protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis

The T Lymphocyte in Experimental Allergic Encephalomyelitis

1990 • 1,005 citations

IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement.

1980 • 835 citations

A monoclonal antibody discriminating between subsets of T and B cells.

1981 • 565 citations

T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination

1985 • 522 citations

T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis

1986 • 471 citations

Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice.

1989 • 372 citations

A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease.

1987 • 368 citations

Experimental Allergic Encephalomyelitis. A Useful Model for Multiple Sclerosis

1984 • 340 citations

Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice

1984 • 311 citations

T cell priming in vivo: a major role for B cells in presenting antigen to T cells in lymph nodes.

1987 • 286 citations

Experimental autoimmune encephalomyelitis (EAE) mediated by T cell lines: process of selection of lines and characterization of the cells.

1982 • 261 citations

Two minor determinants of myelin basic protein induce experimental allergic encephalomyelitis in SJL/J mice.

1988 • 146 citations

Inhibition of murine relapsing experimental autoimmune encephalomyelitis by immune tolerance to proteolipid protein and its encephalitogenic peptides.

1990 • 140 citations

Lymphocytes from SJL/J mice immunized with spinal cord respond selectively to a peptide of proteolipid protein and transfer relapsing demyelinating experimental autoimmune encephalomyelitis.

1991 • 130 citations

The in vitro demyelinating activity of sera from guinea pigs sensitized with whole CNS and with purified encephalitogen

1968 • 115 citations

Experimental allergic encephalomyelitis mediated by murine encephalitogenic T cell lines specific for myelin proteolipid apoprotein.

1987 • 115 citations

Elicitation of experimental allergic encephalomyelitis (EAE) in mice with the aid of pertussigen

1984 • 101 citations

Immunoglobulin-deficient rats fail to develop experimental allergic encephalomyelitis

1983 • 99 citations

Defective induction of antigen‐reactive proliferating T cells in B cell‐deprived mice

1981 • 99 citations

Studies on demyelination by activated lymphocytes in the rabbit eye. II. Antibody-dependent cell-mediated demyelination.

1977 • 98 citations

T cell development in B cell-deficient mice. IV. The role of B cells as antigen-presenting cells in vivo.

1986 • 88 citations

“Allergic” encephalomyelitis

1960 • 78 citations

Opsonization with Antimyelin Antibody Increases the Uptake and Intracellular Metabolism of Myelin in Inflammatory Macrophages

1986 • 74 citations

Studies on Demyelination by Activated Lymphocytes in the Rabbit Eye

1977 • 71 citations

Neuroimmunologic Diseases: Effector Cell Responses and Immunoregulatory Mechanisms

1981 • 70 citations

Intact B-cell activity is essential for complete expression of experimental allergic encephalomyelitis in Lewis rats

1982 • 66 citations

In vivo effect of sera from animals with chronic relapsing experimental allergic encephalomyelitis on central and peripheral myelin

1981 • 65 citations

Cellular Basis of Immune Modulation

1990 • 65 citations

Immunoglobulin deficient rats as donors and recipients of effector cells of allergic encephalomyelitis

1986 • 45 citations

Humoral immune responses to myelin basic protein, cerebroside and ganglioside in chronic relapsing experimental allergic encephalomyelitis of the guinea pig

1985 • 43 citations

Chronic relapsing experimental allergic encephalomyelitis in SJL mice following the adoptive transfer of an epitope-specific T cell line

1989 • 38 citations

Unresponsiveness of MRL/MP-lpr/lpr mice to antigen given subcutaneously in adjuvant: partial restoration of response after local injection of B cells.

1987 • 4 citations