Increased Internalization of p120-uncoupled E-cadherin and a Requirement for a Dileucine Motif in the Cytoplasmic Domain for Endocytosis of the Protein

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Signals for Sorting of Transmembrane Proteins to Endosomes and Lysosomes

2003 • 1,999 citations

The cadherins: cell-cell adhesion molecules controlling animal morphogenesis

1988 • 1,626 citations

Regulation of cadherin-mediated adhesion in morphogenesis

2005 • 1,475 citations

The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species.

1989 • 1,393 citations

Structural basis of cell-cell adhesion by cadherins

1995 • 1,173 citations

Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation.

1989 • 920 citations

The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex.

1988 • 810 citations

Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex.

1995 • 739 citations

A core function for p120-catenin in cadherin turnover

2003 • 714 citations

EEA1, an Early Endosome-Associated Protein.

1995 • 706 citations

Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression.

1994 • 580 citations

Regulation of Cell–Cell Adhesion by Rac and Rho Small G Proteins in MDCK Cells

1997 • 555 citations

Recycling of E-Cadherin

1999 • 538 citations

Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes.

1994 • 490 citations

Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion

2000 • 456 citations

In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death.

1995 • 416 citations

p120-Catenin and p190RhoGAP Regulate Cell-Cell Adhesion by Coordinating Antagonism between Rac and Rho

2006 • 411 citations

Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells

2003 • 399 citations

Molecular organization of the uvomorulin-catenin complex.

1992 • 378 citations

Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function

1997 • 357 citations

Lysosomal Targeting of E-Cadherin: a Unique Mechanism for the Down-Regulation of Cell-Cell Adhesion during Epithelial to Mesenchymal Transitions

2004 • 318 citations

p120-Catenin Regulates Clathrin-dependent Endocytosis of VE-Cadherin

2005 • 261 citations

Regulation of Cadherin Function by Rho and Rac: Modulation by Junction Maturation and Cellular Context

1999 • 257 citations

p120 catenin associates with kinesin and facilitates the transport of cadherin–catenin complexes to intercellular junctions

2003 • 251 citations

Regulation of keratinocyte intercellular junction organization and epidermal morphogenesis by E-cadherin

1992 • 228 citations

Coendocytosis of cadherin and c-Met coupled to disruption of cell-cell adhesion in MDCK cells – regulation by Rho, Rac and Rab small G proteins

1999 • 191 citations

Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments

2004 • 184 citations

Characterization of E-cadherin Endocytosis in Isolated MCF-7 and Chinese Hamster Ovary Cells

2003 • 178 citations

Selective disruption of E-cadherin function in early Xenopus embryos by a dominant negative mutant

1994 • 176 citations

Endocytosis of junctional cadherins in bovine kidney epithelial (MDBK) cells cultured in low Ca2+ ion medium.

1991 • 173 citations

A Dileucine Motif Targets E-cadherin to the Basolateral Cell Surface in Madin-Darby Canine Kidney and LLC-PK1 Epithelial Cells

2001 • 172 citations

p120ctn Binds to the Membrane-proximal Region of the E-cadherin Cytoplasmic Domain and Is Involved in Modulation of Adhesion Activity

1999 • 171 citations

E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles

2003 • 150 citations

An endogenous MDCK lysosomal membrane glycoprotein is targeted basolaterally before delivery to lysosomes.

1991 • 117 citations

Minimal Mutation of the Cytoplasmic Tail Inhibits the Ability of E-cadherin to Activate Rac but Not Phosphatidylinositol 3-Kinase

2003 • 100 citations

Endocytosis of Cadherin from Intracellular Junctions Is the Driving Force for Cadherin Adhesive Dimer Disassembly

2006 • 100 citations

Lateral Dimerization of the E-cadherin Extracellular Domain Is Necessary but Not Sufficient for Adhesive Activity

2002 • 67 citations

Contextual Binding of p120 to E-cadherin at the Basolateral Plasma Membrane in Polarized Epithelia

2003 • 60 citations

Dynamin II Is Involved in Endocytosis but Not in the Formation of Transport Vesicles from the trans -Golgi Network1

1999 • 55 citations

p120-independent Modulation of E-cadherin Adhesion Activity by the Membrane-proximal Region of the Cytoplasmic Domain

2003 • 20 citations