Alterations of surface morphology caused by the metabolism of menadione in mammalian cells are associated with the oxidation of critical sulfhydryl groups in cytoskeletal proteins

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

[44] Glutathione peroxidase

1981 • 2,990 citations

[4] Isolation and use of liver cells

1978 • 1,230 citations

High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and related thiols and disulfides

1980 • 1,179 citations

The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.

1982 • 893 citations

Bleb Formation in Hepatocytes During Drug Metabolism Is Caused by Disturbances in Thiol and Calcium Ion Homeostasis

1982 • 553 citations

Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes

1987 • 533 citations

DT-diaphorase as a quinone reductase: A cellular control device against semiquinone and superoxide radical formation

1982 • 530 citations

Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes

1984 • 411 citations

Menadione-induced cytotoxicity is associated with protein thiol oxidation and alteration in intracellular Ca2+ homeostasis

1984 • 376 citations

Metabolism and reactions of quinoid anticancer agents

1987 • 273 citations

Formation and reduction of glutathione-protein mixed disulfides during oxidative stress

1987 • 267 citations

Identification of two proteins (actin-binding protein and P235) that are hydrolyzed by endogenous Ca2+-dependent protease during platelet aggregation.

1985 • 236 citations

Protective role of the glutathione redox cycle against adriamycin-mediated toxicity in isolated hepatocytes

1981 • 221 citations

Free Radicals in Molecular Biology, Aging, and Disease

1985 • 203 citations

Cytoskeletal and morphologic impact of cellular oxidant injury.

1986 • 190 citations

Menadione-induced bleb formation in hepatocytes is associated with the oxidation of thiol groups in actin

1988 • 168 citations

The metabolism of menadione impairs the ability of rat liver mitochondria to take up and retain calcium.

1982 • 159 citations

Actin microfilaments, cell shape, and secretory processes in isolated rat hepatocytes. Effect of phalloidin and cytochalasin D.

1979 • 136 citations

On the role of thiol groups in the inhibition of liver microsomal ca2+ sequestration by toxic agents

1985 • 93 citations

Catalytic properties of a calmodulin-regulated transglutaminase from human platelet and chicken gizzard.

1985 • 63 citations

Cytoskeleton structure and function

1984 • 43 citations

Cytochalasin B disrupts the association of filamentous web and plasma membrane in hepatocytes

1981 • 41 citations

Association of actin with the platelet membrane

1984 • 18 citations

Formation and identification of cytoskeletal components from liver cytosolic precursors.

1982 • 11 citations