Protective role of the glutathione redox cycle against adriamycin-mediated toxicity in isolated hepatocytes

Glutathione S-Transferases

1974 • 17,321 citations

Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase.

1967 • 10,659 citations

A SPECTROPHOTOMETRIC METHOD FOR MEASURING THE BREAKDOWN OF HYDROGEN PEROXIDE BY CATALASE

1952 • 6,430 citations

Hydroperoxide metabolism in mammalian organs.

1979 • 5,821 citations

The Biology of Oxygen Radicals

1978 • 3,361 citations

A clinicopathologic analysis of adriamycin cardiotoxicity

1973 • 1,534 citations

High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and related thiols and disulfides

1980 • 1,179 citations

Adriamycin: The Role of Lipid Peroxidation in Cardiac Toxicity and Tumor Response

1977 • 1,116 citations

Adriamycin

1974 • 1,051 citations

The estimation of red cell superoxide dismutase activity.

1975 • 1,044 citations

Enzymatic Defenses of the Mouse Heart Against Reactive Oxygen Metabolites

1980 • 711 citations

Glutathione Peroxidase: The Primary Agent for the Elimination of Hydrogen Peroxide in Erythrocytes^*

1963 • 667 citations

Evidence that Peroxidation of Lysosomal Membranes Is Initiated by Hydroxyl Free Radicals Produced during Flavin Enzyme Activity

1973 • 663 citations

Generation of free radicals and lipid peroxidation by redox cycling of adriamycin and daunomycin

1977 • 545 citations

Adriamycin—A Review

1975 • 458 citations

Cardiotoxicity of adriamycin and related anthracyclines

1976 • 377 citations

Effect of glutathione peroxidase activity on lipid peroxidation in biological membranes

1976 • 262 citations

Adriamycin cardiomyopathy—risk factors

1977 • 258 citations

Oxidation in the NADP system and release of GSSG from hemoglobin‐free perfused rat liver during peroxidatic oxidation of glutathione by hydroperoxides

1972 • 257 citations

Adriamycin stimulated superoxide formation in submitochondrial particles

1977 • 256 citations

Formation of monohydroxy-polyenic fatty acids from lipid peroxides by a glutathione peroxidase

1968 • 234 citations

Human Glutathione Reductase: Purification of the Crystalline Enzyme from Erythorocytes

1974 • 215 citations

Inactivation of glutathione reductase by 2-chloroethyl nitrosourea-derived isocyanates

1978 • 188 citations

Severe generalized glutathione reductase deficiency after antitumor chemotherapy with BCNU" [1,3-bis(chloroethyl)-1-nitrosourea].

1977 • 176 citations

Damage to microsomal membrane by lipid peroxidation

1973 • 176 citations

Peroxide removal by selenium-dependent and selenium-independent glutathione peroxidases in hemoglobin-free perfused rat liver.

1978 • 167 citations

The role of methionine in glutathione biosynthesis by isolated hepatocytes

1977 • 159 citations

Familial deficiency of glutathione reductase in human blood cells

1976 • 122 citations

Lipid Peroxidation in Isolated Hepatocytes

1975 • 118 citations

Effect of vitamin E against adriamycin-induced toxicity in rabbits.

1980 • 111 citations

Intracellular mechanisms for the decomposition of a lipid peroxide. II. Decomposition of a lipid peroxide by subcellular fractions

1969 • 94 citations

The effects of α-tocopherol on the toxicity, disposition, and metabolism of adriamycin in mice

1979 • 66 citations

Effect of phenobarbital and diethyl maleate on carbon tetrachloride toxicity in isolated rat hepatocytes

1978 • 60 citations

Adriamycin, BCNU, ftorafur chemotherapy of pancreatic and biliary tract cancer

1979 • 43 citations

The effect of BCNU and adriamycin on normal and G6PD deficient erythrocytes

1979 • 33 citations

Adriamycin, 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU, NSC 409962), cyclophosphamide plus prednisone (ABC-P) in melphalan-resistant multiple myeloma

1978 • 25 citations

Adriamycin, BCNU plus cyclophosphamide (ABC) in advanced carcinoma of the head and neck

1979 • 15 citations