Medroxyprogesterone acetate and cancer cachexia: Interleukin-6 involvement

Prognostic effect of weight loss prior tochemotherapy in cancer patients

1980 • 2,298 citations

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

The biology of interleukin-6

1989 • 1,964 citations

The biology of interleukin-6

1989 • 1,459 citations

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

1985 • 1,125 citations

The Immune-Hypothalamic-Pituitary-Adrenal Axis*

1989 • 671 citations

Progestin Regulation of Cellular Proliferation*

1990 • 659 citations

Evidence for the involvement of interleukin 6 in experimental cancer cachexia.

1992 • 648 citations

Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias.

1989 • 501 citations

INTERLEUKIN-6 STIMULATES ANTERIOR PITUITARY HORMONE RELEASEIN VITRO.

1989 • 323 citations

Controlled Trial of Megestrol Acetate for the Treatment of Cancer Anorexia and Cachexia

1990 • 320 citations

Progesterone antagonism of the oestrogen receptor and oestrogen-induced uterine growth

1975 • 273 citations

Total Parenteral Nutrition in the Cancer Patient

1981 • 271 citations

Total parenteral nutrition and cancer clinical trials

1986 • 247 citations

Human glioblastoma cells release interleukin 6 in vivo and in vitro.

1990 • 237 citations

Constitutive production of interleukin 6 by ovarian cancer cell lines and by primary ovarian tumor cultures.

1990 • 226 citations

Immune-neuroendocrine circuits: integrative role of cytokines.

1992 • 207 citations

Serum interleukin 6 levels are elevated in lymphoma patients and correlate with survival in advanced Hodgkin's disease and with B symptoms.

1993 • 169 citations

Interleukin involvement in anterior pituitary cell growth regulation: effects of IL-2 and IL-6.

1993 • 163 citations

Interleukin 6 decreases cell-cell association and increases motility of ductal breast carcinoma cells.

1989 • 158 citations

Expression of the interleukin 6 receptor and interleukin 6 in prostate carcinoma cells.

1990 • 154 citations

Interleukin-6 immunoreactivity in human tumors.

1989 • 136 citations

A controlled, prospective, randomized trial evaluating the metabolic effects of enteral and parenteral nutrition in the cancer patient

1982 • 125 citations

Cytokines and the hypothalamic-pituitary-adrenal axis

1990 • 107 citations

The Effect of Medroxyprogesterone Acetate on the Pituitary-Adrenal Axis

1976 • 102 citations

Interleukin-6 cDNA transfected Lewis lung carcinoma cells show unaltered net tumour growth rate but cause weight loss and shortened survival in syngeneic mice

1993 • 80 citations

Interleukin 6 is secreted by breast fibroblasts and stimulates 17β‐oestradiol oxidoreductase activity of MCF‐7 cells: Possible paracrine regulation of breast 17β‐oestradiol levels

1991 • 77 citations

Hydrazine sulfate influence on nutritional status and survival in non-small-cell lung cancer.

1990 • 75 citations

Pharmacokinetic and pharmacodynamic basis for the treatment of metastatic breast cancer with high-dose medroxyprogesterone acetate

1984 • 71 citations

Influence of hydrazine sulfate on abnormal carbohydrate metabolism in cancer patients with weight loss.

1984 • 66 citations

Hydrazine sulfate in cancer patients with weight loss. A placebo-controlled clinical experience

1987 • 65 citations

High-dose pilot studies in extensive-stage small-cell lung cancer.

1986 • 64 citations

Treatment of advanced breast cancer with megestrol acetate after therapy with tamoxifen

1982 • 63 citations

Effect of adjuvant central iv hyperalimentation on the survival and response to treatment of patients with small cell lung cancer: a randomized trial.

1985 • 62 citations

An overview of megestrol acetate for the treatment of advanced breast cancer.

1988 • 55 citations

Anticachectic activity of 5'-deoxy-5-fluorouridine in a murine tumor cachexia model, colon 26 adenocarcinoma.

1990 • 53 citations

Interleukin 6 stimulates the production of immunoreactive endothelin 1 in human breast cancer cells.

1993 • 48 citations

Oral medroxyprogesterone acetate in the treatment of metastatic breast cancer

1985 • 48 citations

Abundant expression of immunoreactive endothelin 1 in mammary phyllodes tumor: possible paracrine role of endothelin 1 in the growth of stromal cells in phyllodes tumor.

1992 • 41 citations

Decreased adherence of interleukin 6-treated breast carcinoma cells can lead to separation from neighbors after mitosis.

1991 • 37 citations

Medroxyprogesterone acetate treatment reduces serum interleukin-6 levels in patients with metastatic breast carcinoma

1996 • 29 citations

An evaluation of high-dose medroxyprogesterone acetate (MPA) therapy in women with advanced breast cancer

1984 • 26 citations

The value of parenteral nutrition support: Chemotherapy and radiation treatment

1986 • 21 citations

INTERFERENCE OF GESTAGENS AND ANDROGENS WITH RAT UTERINE OESTROGEN RECEPTORS

1978 • 21 citations

Medroxyprogesterone acetate inhibits human pancreatic carcinoma cell growth by inducing apoptosis in association with Bcl-2 phosphorylation

2000 • 20 citations

Tissue-type plasminogen activator predicts endocrine responsiveness of human pancreatic carcinoma cells

1995 • 12 citations

PRIMARY TUMOR LEVELS OF INTERLEUKIN-6 IN RELATION TO TUMOR BURDEN IN HUMAN BREAST-CANCER

1994 • 4 citations

FIBROBLAST-TUMOR INTERACTION CHANGES CONSTITUTIVE EXPRESSION OF IL-6 AND IL-8 IN HUMAN CARCINOMA-CELLS

1995 • 4 citations