Interleukin 6 is secreted by breast fibroblasts and stimulates 17β‐oestradiol oxidoreductase activity of MCF‐7 cells: Possible paracrine regulation of breast 17β‐oestradiol levels

The biology of interleukin-6

1989 • 1,964 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

The biology of interleukin-6

1989 • 1,459 citations

AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6.

1990 • 500 citations

Two interferon mRNAs in human fibroblasts: in vitro translation and Escherichia coli cloning studies.

1980 • 341 citations

Endotoxemia elicits increased circulating beta 2-IFN/IL-6 in man.

1989 • 323 citations

Autocrine and paracrine growth regulation of human breast cancer

1986 • 293 citations

Autocrine Growth Stimulation of the MCF 7 Breast Cancer Cells by the Estrogen-Regulated 52 K Protein*

1986 • 273 citations

Synthesis and secretion of multiple forms of beta 2-interferon/B-cell differentiation factor 2/hepatocyte-stimulating factor by human fibroblasts and monocytes.

1988 • 254 citations

IL-6/IFN-beta-2 as a circulating hormone. Induction by cytokine administration in humans.

1989 • 201 citations

THE RELATIONSHIP BETWEEN 17β‐HYDROXYSTEROID DEHYDROGENASE ACTIVITY AND OESTROGEN CONCENTRATIONS IN HUMAN BREAST TUMOURS AND IN NORMAL BREAST TISSUE

1983 • 188 citations

Growth inhibition of human breast carcinoma and leukemia/lymphoma cell lines by recombinant interferon-beta 2.

1988 • 182 citations

Progestin Effect on Cell Proliferation and 17β-Hydroxysteroid Dehydrogenase Activity in Normal Human Breast Cells in Culture*

1986 • 175 citations

Effects of serum and insulin on the sensitivity of the human breast cancer cell line MCF-7 to estrogen and antiestrogens.

1981 • 138 citations

Secretory proteins induced in human fibroblasts under conditions used for the production of interferon beta.

1982 • 125 citations

Estrone and estradiol content in human breast tumors: Relationship to estradiol receptors

1977 • 105 citations

Mitogenicity of human fibroblasts in vivo for human breast cancer cells

1987 • 89 citations

Effects of human breast fibroblasts on growth and 17β-estradiol dehydrogenase activity of MCF-7 cells in culture

1988 • 82 citations

Interleukin 6 in Infection and Cancer

1990 • 73 citations

Paracrine influence of human breast stromal fibroblasts on breast epithelial cells: Secretion of a polypeptide which stimulates reductive 17β‐oestradiol dehydrogenase activity

1988 • 64 citations

Steroidal regulation of oestradiol-17β dehydrogenase activity of the human breast cancer cell line MCF-7

1988 • 62 citations

O‐ and N‐glycosylation lead to different molecular mass forms of human monocyte interleukin‐6

1989 • 60 citations

Appearance of hybridoma growth factor/interleukin-6 in the serum of mice bearing a methylcholanthrene-induced sarcoma

1988 • 40 citations

The effect of epidermal growth factor, transforming growth factor and breast tumour homogenates on the activity of oestradiol 17β hydroxysteroid dehydrogenase in cultured adipose tissue

1986 • 35 citations

The effect of hydrocortisone on the accumulation of amylase in embryonic chick pancreas

1969 • 34 citations

Metabolism of [3H]oestradiol in vivo by normal breast and tumour tissue in postmenopausal women

1986 • 27 citations

Measurement of cytokine production by the monocytic cell line mono mac 6 using novel immunoradiometric assays for interleukin-1β and interleukin-6

1991 • 20 citations

17β-Hydroxysteroid dehydrogenase activity in leiomyoma and myometrium and its relationship to concentrations of oestrone, oestradiol and progesterone throughout the menstrual cycle

1985 • 11 citations